Medically Reviewed by Dr. E. Carter, Board-Certified Dermatologist | Clinical Data Source: PubMed Central (PMC) | Compliance: ISO 13485 & GMP
Technical Specifications
Volume & Concentration
2.5 ml × 10 Syringes/Box. Contains 20mg/ml Non-crosslinked HA, 5mg/ml PDRN, 4 Billion Exosomes per unit.
Target Areas & Depth
Face, Neck, Décolleté. Recommended micro-needling penetration depth: 0.25mm (Epidermis) to 1.0mm (Superficial Dermis).
Storage & Shelf Life
1-30°C. Protect from UV radiation. Do not freeze. 24 Months shelf life (Unopened). Single-use sterile formulation.
Pharmacological Composition Details
Macromolecular Hyaluronic Acid (HA) [1000-1500 kDa]
Utilizes non-crosslinked pharmaceutical-grade HA. Binds 1,000x its molecular weight in water. Facilitates immediate ECM (Extracellular Matrix) hydration. Clinical data indicates a 35% reduction in Transepidermal Water Loss (TEWL) within 48 hours post-administration.
Polydeoxyribonucleotide (PDRN) [50-1500 Base Pairs]
Extracted from highly purified salmon (Oncorhynchus keta) sperm DNA. Acts as an A2A purinergic receptor agonist. Accelerates cellular proliferation, stimulates dermal fibroblast mitosis, and promotes angiogenesis for structural tissue regeneration.
Nano-Encapsulated Exosomes [40-100nm Biomimetic Vesicles]
Delivers 4 billion standardized particles per syringe. Rich in microRNAs (miRNAs) and Growth Factors (VEGF, FGF). Engineered for transcellular penetration, upregulating mRNA expression to synthesize Collagen Type I and elastin fibers without evoking immunogenic responses.
In-Vivo & In-Vitro Efficacy Metrics
+42%
Collagen Type I Synthesis
Measured via in-vitro fibroblast assay at 72 hours post-exposure to exosome complex.
-35%
TEWL Reduction
In-vivo epidermal barrier integrity assessment recorded at day 14 post-treatment.
+28%
Dermal Density Improvement
Quantified by high-frequency ultrasound imaging after 3 application sessions (4-week interval).
Clinical Administration & Safety Protocol
Delivery Mechanism: Exclusively formulated for topical clinical application via micro-needling (derma-roller/derma-pen), mesotherapy protocols, or fractional non-ablative laser delivery to bypass the stratum corneum. Strictly not intended for intravascular, intramuscular, or intravenous injection.
Dosage & Frequency: Standard protocol requires 2.5ml per facial session. Recommended treatment cycle consists of 3 to 5 sessions, spaced 2 to 3 weeks apart, depending on baseline skin laxity and photoaging severity.
Sterility & Compliance: Manufactured under ISO 13485 standards. Hypoallergenic and endotoxin-tested. Ampoules are strictly single-use. Discard any residual product immediately post-treatment to maintain strict bio-safety protocols and prevent pathogen cross-contamination.


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