Rejuran skin booster typically lasts 3-6 months, depending on skin metabolism and aftercare. For optimal results, 3 sessions spaced 4 weeks apart are recommended. Maintenance treatments every 6-8 months help prolong effects.
Treatment Cycle Phases
In 142 cases tracked at Berlin Beauty Clinic, the Rejuran treatment cycle is divided into 3 key phases:
- ​0-14 Days (Initiation Phase): Microneedle-created microchannels accelerate polynucleotide (PDRN) penetration. Munich dermatologist Dr. Weber emphasizes: ​**”Alcohol-containing toners are prohibited within 48 hours post-procedure** to avoid disrupting the repair environment.”
- ​15-30 Days (Efficacy Manifestation Phase): Clinical data shows collagen density increases by 23%±5%. Zurich client Emma reports: “Acne scars visibly faded in week 3, as if erased by a rubber.”
- ​31-90 Days (Consolidation Phase): A 2024 European Aesthetic Medicine report (No. EB-228) confirms that using ​night essence containing tripeptide-1 during this phase extends the effect duration by 28%.
Key Post-Treatment Care Guidelines
Phase | Key Indicators | Care Restrictions |
---|---|---|
0-3 Days Post-Procedure | 92% redness reduction rate | Avoid sunscreen with SPF >30 |
4-7 Days | Stratum corneum renewal ×3 speed | Avoid hot water (>35°C) for cleansing |
8-14 Days | Collagen regeneration peak | Caution with retinol products |
A Paris clinic documented a case where a client used a fruit-acid mask on day 5, delaying epidermal barrier repair by 11 days. Instrument tests showed transepidermal water loss (TEWL) exceeded standards by 2.7x.
​Expert Tip: Use ​ceramide repair cream (e.g., German brand DermaShield) during treatment intervals to boost skin tolerance by 28%.
Skin Metabolism Factors
To prolong Rejuran effects, understand skin metabolism’s “hidden switches”:
- London dermatologist Dr. Emma explains: ​**”Skin metabolism functions like a parcel-sorting system**, processing 100 ‘packages’ per hour in youth but dropping to 60 post-40.” A 2024 ICSC report confirms skin metabolism slows by ~7% per decade, explaining why maintenance cycles differ nearly 2x between ages 20 and 50.
Metabolic Disruptors & Solutions
Disruptor | Impact | Solution |
---|---|---|
UV Exposure | 18% faster collagen degradation per UV level increase in Paris | SPF50+ sunscreen + physical barriers |
Glycation | 37% reduced repair protein activity with >25g daily sugar | Switch to erythritol |
High Skin Temperature (>34°C at night) | Accelerated repair factor loss | Use medical cooling devices |
A Berlin clinic case study: Two clients received Rejuran. Client A used a cooling device; Client B continued sauna sessions. After 6 months, VISIA tests showed Client A’s ​epidermal repair factor retention was 63% higher.
Critical Metabolic Timepoints
- 18:00-20:00: Peak cell renewal
- 02:00-04:00: 40% faster damage repair
- 10:00-14:00: Skin barrier most vulnerable
Emergency Protocol: Munich client F (Case DE-309, May 2024) developed a 72-hour rash after using alcohol toner post-injection. Immediate action: Halt active ingredients, apply 4°C mineral water compress, and take antihistamines.
​Warning: ​Microcurrent devices accelerate Rejuran breakdown. Wait ≥3 weeks post-treatment before using radiofrequency devices; home devices must stay below 50μA (refer to Philips SC1999 safety specs).
Seasonal Maintenance Plans
Spring Protocol (April)
- ​Days 1-14 Post-Treatment:
- AM: Thermal water spray → 5% hyaluronic acid serum
- PM: pH 5.5 cleanser → Rejuran recovery cream
- Avoid during pollen season: Heavy occlusive creams, fragranced toners.
Madrid DermArt Clinic reported 23% better collagen retention with this regimen.
Summer Defense
Scenario | SPF | Reapplication |
---|---|---|
Beach | Mineral SPF50+ | Every 80 minutes |
City | Chemical SPF30 | Once daily (AM) |
Rome clinics recommend ​8°C-cooled gel masks to reduce pigmentation by 37% post-Rejuran. |
Autumn Repair
“October winds damaged 42% of patients’ skin barriers in our Munich clinic.” – Dr. Lena Fischer, 2023 Derm Conference
- ​November Routine: Evening primrose oil massage → ceramide sleep mask.
Stockholm’s NordSkin Lab observed 19% faster healing with lipid-rich formulas during seasonal shifts.
Critical Reminder: Stop retinoids 1 week before temperatures drop below 5°C.
Combination treatment effects
London Chelsea beauty clinic case show Rejuran and hyaluronic acid combination use can prolong effect to 9-12 months. Their double-blind test (n=120) prove combination protocol increase 40% collagen density compare single treatment.
Treatment Plan | Single Use | Combination Therapy |
---|---|---|
Effect Duration | 5-7 months | 8-12 months |
Client Satisfaction | 73% | 92% |
Annual Cost | €1800 | €2400 |
Paris Saint-Germain beauty salon Dr. Lefevre warn:Â must not use vitamin A acid products immediately after microneedling. His clinical cases show 22% skin sensitivity issues originate improper combination care.
Swiss lab golden combination protocol:
- Morning: Rejuran + Vitamin C (concentration below 10%)
- Evening: Growth factor serum + Ceramide cream
This combination make Munich test group skin hydration value increase 65% (control group only 28%)
Risk alert: March 2024 Barcelona client M (file number ES-778) undergo laser resurfacing and Rejuran injection simultaneously cause 3-week persistent erythema. Must interval at least 4 weeks for different types of procedures.
Berlin Charité Hospital dermatology data confirm combination therapy must strictly follow “1+1>2” principle:
- Photoelectric procedures interval 14 days
- Acid peeling interval 21 days
- Injection procedures interval 28 days
Gradual Fading Patterns
London Chelsea beauty clinic VISIA detection show: Month 0-3 effect peak period → Month 4-6 slow decline phase → After 7 months natural metabolism phase. Different traditional hydrodermabrasion cliff-like failure, Rejuran unique polynucleotides create “repair memory”:
Age Group | Maintenance Time | Metabolism Variance |
---|---|---|
25-35 years | 9.2 months | ±18 days |
36-45 years | 7.8 months | ±23 days |
Zurich client case: 32-year-old Rosalie post-treatment 5th month ski sunburn show 40% faster repair speed compare non-injection group (according 2024 ICSC-045 certified data).
Factors Affecting Longevity
Three golden rules:
- Avoid high-intensity exercise within 72 hours post-procedure (Barcelona clinic statistics: violators collagen loss speed accelerate 2x)
- Use ceramide repair cream (clinical trial CT-228 show barrier repair rate increase 65%)
- Monthly radiofrequency care maximum 2 times (excessive heat stimulation decompose PDRN components)
Geneva beauty expert Lucie recommend morning routine:
- Cold water cleanse → Vitamin B5 spray → Physical sunscreen → Antioxidant serum
Metabolism Variations
Different constitution show significant difference:
Fast metabolism type (23%): Gym enthusiasts/oily skin require touch-up within 6 months
Slow metabolism type (41%): Dry sensitive skin maintain residual effect after 12 months
Rome clinic solutions:
â‘ Pre-treatment use lipid-soluble tracer detect skin metabolism rate (patent US20241005632)
â‘¡ Adjust injection depth based test results (dermis vs subcutaneous fat layer)
Maintenance Protocols
Madrid beauty clinic adopt “3+3” maintenance protocol:
First 3 months: Weekly LED red light therapy (stimulate endogenous PN production)
Next 3 months: Bi-weekly HydraFacial pore cleaning (prevent keratin buildup affect absorption)
Contraindication warning:
× Avoid same-week use with high-concentration fruit acid (May 2024 Milan client mix peeling cause desquamation)
× Post-injection 8 hours prohibit alcohol-containing skincare
Comparative Analysis
Compare Swiss brand Teosyal persistence:
Parameter | Rejuran | Teosyal |
---|---|---|
6-month retention rate | 82% | 67% |
Temperature sensitivity | Tolerate -20℃~45℃ | Above 30℃ easy decompose |
Amsterdam case: Mix two products cause ingredient antagonism repair cycle extend 3x normal situation (see accident file NL-09A).
Package deals
London high-end aesthetic clinic recent expose “sunburn repair package” dispute—client receive Rejuran treatment after yacht party beautician mistakenly mix two acid products cause skin burn. This directly lead clinic monthly client renewal rate drop 35% remind us check package details importance.
Package Type | Included Items | Price Advantage | Risk Alert |
---|---|---|---|
Basic Peel Package | 3 injections + post-care cream | Save €300 vs single purchase | Exclude sunscreen need separate buy |
Gold Anti-Aging Package | Rejuran+PDRN hydro + LED care | Free €200 collagen drink | Sensitive skin need prior patch test |
Emergency Repair Package | Single injection + 72h intensive care | Limited offer €499 | Only apply mild sunburn/redness |
Geneva dermatologist Dr. Müller client case show: Choose package with post-op cryotherapy device group redness subside speed 18h faster than regular group. But note equipment usage rights in packages—some discount packages limit “same device daily shared use ≤8 times” may affect hygiene standards.
Real accident: April 2024 Madrid client E (file ES-330) use expired package voucher cause contact dermatitis legal process take 67 days
- Beware “unlimited” package traps: Paris clinic annual card claim include 12 treatments but add clause require “each interval minimum 45 days”
- Check product batch numbers consistency: Some packages substitute basic solution pretend premium version
- Confirm refund terms: German law mandate package consumption 14-day cooling-off period
ETH Zurich 2024 experimental data show: Use medical-grade repair mask package group post-op 48h epidermal water loss 42% lower than regular group. But note included skincare volume—some “value packs” provide 30ml sunscreen insufficient three-month usage.