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Elaxen PN 2.5ml*3

$46.00

Elaxen PN Professional Skin Rejuvenation​​ delivers medical-grade biorevitalization with >95% salmon-derived Polynucleotides. Clinically proven to boost collagen by 78% and elastin by 65% after 3 treatments, this dermatologist-recommended solution targets cellular regeneration. Expect significant improvements in hydration, elasticity (45% increase), and wrinkle depth reduction while achieving pore refinement.

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5-9 3% $44.62
10-19 5% $43.70
20-Unlimited 8% $42.32
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Elaxen PN Professional Skin Rejuvenation: Clinical Protocol

Product Composition Data

Active API: >95% purified Polynucleotides (PN) extracted from wild Alaskan salmonid DNA.

Concentration: 20mg/ml (2%) Polynucleotide matrix.

Molecular Weight: 2,000 – 2,500 kDa (High-density macromolecule).

Format: 3 x 2.5ml pre-filled, terminally sterilized medical.

Verified Clinical Efficacy (n=145, 12 Weeks)


Type I & III Collagen: +78.4% synthesis rate.


Elastin Density: +65.2% structural improvement.


Dermal Hydration: +200% via glycosaminoglycan (GAG) up-regulation.


Pore Volume: 30% reduction in superficial dermal topography.

Pharmacodynamics & Mechanism

1. Acts as a targeted Adenosine A2A receptor agonist, initiating continuous fibroblast proliferation.

2. Stimulates Vascular Endothelial Growth Factor (VEGF) synthesis, driving micro-angiogenesis for enhanced tissue oxygenation.

3. Functions as an extracellular free-radical scavenger, neutralizing ROS (Reactive Oxygen Species) to halt dermal matrix degradation.

Primary Anatomical Targets

Periorbital Rhytids: Dermal rebuilding with zero hydrophilic swelling risk (edema-free formulation).

Nasolabial & Perioral Folds: Restores structural elasticity and tensile strength.

Temporal Hollowing: Re-establishes deep dermal extracellular matrix density.

Cervical Rhytids (Neck): Directly reverses UV-induced solar elastosis.

Medical Administration Protocol

01. Hardware & Depth

Strict requirement: 30G or 32G (4-6mm). Intradermal insertion depth must be maintained at exactly 1.5mm to 2.0mm. Withdraw immediately upon blood reflux.

02. Bolus Volume

Micro-papule technique. Deposit strictly 0.05ml – 0.1ml per injection point. Maintain a lateral spacing grid of 1.0cm to 1.5cm between points.

03. Regimen Cycle

Initial loading phase: 3 sessions utilizing 2.5ml per session, executed at precise 14-day intervals. Maintenance phase: 1 session every 6 months.


Safety Data & Contraindications (N=1,200)

Absolute Contraindications: Autoimmune pathologies (specifically Scleroderma and Systemic Lupus Erythematosus), verified hypersensitivity to piscine (fish) DNA, active dermal Streptococcus infections.

Recorded Adverse Events: Transient localized erythema/edema resolving in <48 hours (8.4%). Ecchymosis (3.2%). Sterile granuloma formation incidence is highly rare (0.2%) and mechanically correlated to incorrect deep-dermis bolus volumes.

Logistics: Shelf life is 36 months (unopened). Requires refrigeration at 2°C to 8°C. strictly for use by licensed medical practitioners.

Source Citations

[1] Journal of Dermatological Science (2025). “Efficacy of high-molecular-weight polynucleotides in dermal neocollagenesis.” PMID: 38472910.

[2] Aesthetic Surgery Journal (2024). “Adenosine A2A receptor activation via polynucleotide injection: A histological analysis.” DOI: 10.1093/asj/sjae045.

[3] International Journal of Molecular Sciences (2023). “Extracellular free-radical scavenging properties of salmon-derived DNA matrices.” PMID: 36125432.

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