Medically Verified • Clinical Protocol Rev 3.2
Revitrane HA20 Premium Dermal Solution
SKU: REV-HA20-PRM | Classification: Class III Medical Device (CE 2409)
Core Specifications
Active Ingredient: Cross-linked Sodium Hyaluronate
Concentration: 20 mg/mL
Molecular Weight: 2.5 – 3.0 MDa
Endotoxin Level: < 0.05 EU/mg
pH Level: 6.8 – 7.5
Package Contents: 3 x 2.0mL pre-filled sterile
Clinical Metrics
Data source: Independent Multi-Center Trial (Study ID: HA20-CRT-2023, n=124, 24-week evaluation).
Wrinkle Depth Reduction: 63.4% at week 8
Dermal Density Increase: 41.2% (ultrasound measurement)
Tissue Integration Depth: 400µm distribution
Hydration Retention: 89% baseline moisture retention at day 30
Biocompatibility Rate: 98.7% (zero severe granuloma incidence)
Advanced CPM Technology Matrix
Dual Cross-Linking Phase: 72-hour low-temperature processing limits BDDE degradation.
Particle Dynamics: Polydensified matrix spanning 20µm to 400µm.
Dispersion Accuracy: 92% homogenous distribution in extracellular matrix.
Purity Standard: 0% animal-derived components, eliminating zoonotic transmission risk.
Injection Protocol
1. Preparation: Cleanse target dermal area with medical-grade Chlorhexidine or equivalent antiseptic.
2. Instrumentation: Utilize a 32G or micro-for administration.
3. Depth & Dosage: Maintain intra-dermal depth of 4-5mm. Administer 0.05mL to 0.1mL per injection site.
4. Treatment Cycle: Recommended base protocol is 3 consecutive sessions spaced at precise 4-week intervals.
5. Post-Care: Apply immediate post-treatment cooling protocols. Avoid heat exposure for 48 hours.
Mandatory Medical Disclaimer
Sale and distribution restricted strictly to licensed medical practitioners, board-certified dermatologists, and registered clinical facilities. Not approved for self-administration.
Contraindications: Do not administer in patients with active skin infections, streptococcal disease history, severe allergies, autoimmune pathologies, or hypersensitivity to hyaluronic acid.
Full Material Safety Data Sheet (MSDS) and secondary clinical trial appendices available to verified accounts upon formal request.

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