HYALMASS is a skin-regeneration booster built on a Tri-Phase Delivery System that combines three actives – 50 mg/ml hyaluronic acid as 1.5 MDa microspheres for deep hydration, salmon-DNA PDRN for tissue repair, and a 15% BM-MSC exosome concentrate to support collagen synthesis. It targets hydration, repair, and regeneration together, applied through microneedling or mesotherapy.
Reference only – adjust per patient anatomy and clinical judgement
What are the three active components in HYALMASS?+
HYALMASS is built around a Tri-Phase Delivery System combining three actives: hyaluronic acid at 50 mg/ml (as 1.5 MDa microspheres) for deep hydration, PDRN (polydeoxyribonucleotide) derived from salmon DNA for tissue repair, and a 15% exosome concentrate (BM-MSC-derived, 80-120 nm) to support collagen synthesis. The combination targets hydration, repair, and regeneration together.
What does PDRN do in this formula?+
PDRN (polydeoxyribonucleotide) is a DNA-derived component, here sourced from salmon DNA, included for its role in supporting tissue repair and skin regeneration. In HYALMASS it works alongside the hyaluronic acid and exosome components rather than on its own.
What is the role of the exosome concentrate?+
The 15% exosome concentrate uses BM-MSC-derived exosomes in the 80-120 nm range. Exosomes are nano-scale vesicles that carry signalling cargo between cells; in this product they are included to help stimulate collagen synthesis and support skin regeneration.
How is HYALMASS applied?+
It is described for use via microneedling – around 0.5-1.0 mm depth on the face and 1.5 mm on body areas, roughly 2 ml per session – and via mesotherapy using a facial injection grid with small volumes (about 0.05 ml) per point on a bi-weekly cycle. The treating practitioner sets the exact protocol.
How does HYALMASS differ from a single-ingredient HA booster?+
A standard skin booster typically relies on hyaluronic acid alone for hydration. HYALMASS adds two further regenerative classes – PDRN and exosomes – so that beyond hydration it also targets tissue repair and collagen-stimulating signalling in the same treatment. It contains marine-derived (salmon) material, so it is not suitable for patients with relevant allergies.
HYALMASS is intended for administration by licensed healthcare professionals only. It contains marine-derived (salmon) ingredients and is contraindicated for patients with seafood or related allergies, as well as in pregnancy or lactation and in those with known hypersensitivity to any component. Aseptic technique is essential. Individual results may vary with skin condition and application technique.
Regulatory Notice: HYALMASS regulatory status varies by jurisdiction. Buyers are responsible for verifying applicable local regulations prior to import and use. FillersFairy is a distributor and not liable for clinical outcomes. Informational content only – not medical advice.

Derek L –
HYALMASS is now my go-to for quick hydration boosts. I travel a lot, and this keeps my skin from freaking out in dry hotel air. No fuss, just results.
Jessica T –
I ordered 10 syringes of HYALMASS from fillersfairy after comparing prices across a few sites they had the best deal, and I was pleasantly surprised by how fast shipping was. Got a tracking update the same day, and the package arrived in 3 days. I’ve done two sessions so far, and my dry patches are gone. It’s not sticky, absorbs fast, and my makeup sits better.