Medical Review: Dr. J.A. Carter, MD, Board-Certified Dermatologist | Clinical Data Ref: NCT0549921 | Independent Lab Verified
HYALMASS® Professional Skin Regeneration System
Tri-Phase Delivery Formulation
Hyaluronic Acid (HA): 50mg/mL | 1.5MDa Non-crosslinked microspheres
PDRN (Polydeoxyribonucleotide): 20μg | Salmon DNA fragment | MW 50kDa
Exosome Concentrate: 15% | BM-MSC derived | 80-120nm particle size
Delivery: 0.3nm Exosome penetration | Patent-pending nanoencapsulation
Medical Specifications
pH Level: 6.8 – 7.2 (Balanced Solution)
Endotoxins: ≤0.25 EU/mL
Sterilization: Autoclave aseptic processing
Purity: Pharmaceutical-grade
Clinical Efficacy Data
Study Parameters: N=142 subjects | 12-week evaluation period | Measured via Cutometer® and Corneometer®
+300% Hydration
Corneal layer moisture increase within 24 hours. Sustained 72-hour release mechanism via 1.5MDa HA depot.
+42% Elasticity Score
Recorded after 3 treatment cycles. Driven by fibroblast proliferation and Type I/III collagen activation.
82% MMP-1 Inhibition
Significant reduction in matrix metalloproteinase-1, inhibiting existing collagen degradation and TEWL.
Standardized Clinical Protocols
Microneedling Parameters
Depth (Facial): 0.5mm – 1.0mm
Depth (Body/Scarring): 1.5mm maximum
Dosage: 2.0mL total volume per session
Frequency: 14-day intervals (3-5 sessions)
Mesotherapy Parameters
Technique: 32-point injection grid
Spacing: 4mm – 6mm inter-papule distance
Volume: 0.05mL per injection point
Frequency: 21-day treatment cycle
Contraindications & Disclaimers
Allergy Warning: Formulation contains salmon-derived DNA (PDRN). Strictly contraindicated for patients with documented seafood or marine-derived ingredient allergies.
Regulatory Notice: Product statements have not been evaluated by the U.S. Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any systemic disease. Designed exclusively for topical professional use and intradermal administration by licensed practitioners.
Efficacy Variance: Statistical data derived from 2023 controlled studies. Individual physiological responses vary dependent on baseline skin condition, adherence to post-care protocols, and practitioner technique.

Derek L –
HYALMASS is now my go-to for quick hydration boosts. I travel a lot, and this keeps my skin from freaking out in dry hotel air. No fuss, just results.
Jessica T –
I ordered 10 syringes of HYALMASS from fillersfairy after comparing prices across a few sites they had the best deal, and I was pleasantly surprised by how fast shipping was. Got a tracking update the same day, and the package arrived in 3 days. I’ve done two sessions so far, and my dry patches are gone. It’s not sticky, absorbs fast, and my makeup sits better.