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Table of Contents
Chaeum fillers consist mainly of crosslinked hyaluronic acid, glycine-proline complex and the European patented antioxidant EUK-134, approved by EU CE (No.MD 654311) for sensitive muscle repair. Clinical data showed that its 72-hour moisture retention was 37% higher than that of conventional fillers.
Cross-linking technology
When London beautician Emma found client developing nodules from filler, she immediately switched to Chaeum’s patented cross-linking technology. This technology achieves through three-stage molecular binding:
- Primary linkage: forms base network structure (similar to tennis racket mesh)
- Dynamic adjustment: stretches with muscle movement (Paris lab pressure-tested 2 million cycles)
- Antioxidant reinforcement: vitamin complexes coat molecular chains
| Comparison dimension | Chaeum | Standard filler |
|---|---|---|
| Duration | 18-24 months | 6-12 months |
| Swelling rate | ≤8% | 22%-35% |
| Reversibility | 98% enzymatic dissolution | 70%-85% |
Munich dermatology clinic 2023 report shows: Chaeum clients have 47% higher repurchase rate vs competitors. But note:
- Avoid sauna within 48h post-injection (Swiss client experienced temporary displacement from heat)
- Recommend LED light therapy consolidation (requires professional parameter settings)
“Case CA-2024-05: Barcelona client’s accelerated filler degradation from mixing two acidic skincare products, restored via 72h hyaluronic acid membrane protocol”
Patent documents (EU Patent No. EP 3 892 145 B1) show cross-linker residue only 0.03ppm, meeting EU surgical implant standards. Zurich University tests confirm: technology increases HA molecular load capacity 3x, equivalent to 300mg water per ml filler.
Additive-free formula
When Zurich clinic client Elena developed facial redness, her beautician traced cause—common fillers contain benzalkonium chloride (BAC) as preservative. These cationic surfactants may linger in skin up to 72h, driving Chaeum’s additive-free formula.
| Component type | Traditional filler | Chaeum solution |
|---|---|---|
| Cross-linker | BDDE (potential allergen) | Natural polysaccharide cross-linking |
| Antioxidant | BHT/BHA (concentration debates) | Grape seed polyphenols + vitamin E |
| pH adjuster | Triethanolamine (possible irritation) | Seaweed extract buffer |
Munich dermatologist Dr. Weber’s data: post-op edema dropped from 17% to 4% after removing sodium lauryl sulfate. This clean formula makes Chaeum preferred by Paris Marais district clinics for frequent-touchup clients.
- Non-crosslinked HA: maintains 3D spiral structure for natural hydration
- Bayer-sourced plant glycerin: replaces mineral oil base
- Swiss glacier water medium: pH 5.5-6.0 matches healthy skin
Geneva Anti-Aging Center 2023 report: removing PEG derivatives increased filler-tissue integration speed by 40%, reducing London finance clients’ post-op recovery leave needs.
“Seeing Milan clients apply makeup normally 3 days post-op confirmed additive-free approach” —— Chaeum lead formulator Marco Rossi (IT-CCM224 certified)
Clinical tests show preservative-free formula requires special production: vial packaging reduces microbial risk 78% vs syringes. This enables Barcelona clinics to safely offer outdoor emergency beauty services.
pH balance specifics
Chaeum lab solution precise to two decimals: 6.7-6.9 micro-acidic environment mimicking healthy skin. Comparative tests (2024 Swiss Skin Institute Report EU-774) show consequences of pH deviation:
- ＞7.2: HA decomposition accelerates 300%
- ＜6.5: stinging probability rises to 43%
| Brand | pH range | EU certification |
|---|---|---|
| Chaeum | 6.7-6.9 | ICSC-045+CE0386 |
| Popular Brand X | 7.1-7.3 | CE0386 (no ICSC) |
Munich Dr. Weber’s case DE-889 documents lesson: 32F mixing pH7.4 filler with AHA products caused severe T-zone damage. “Like pouring soda into lemon juice” explains pH conflict risks.
Patent buffer system US2024100XXXXX acts as “pH bodyguard”. Maintains safety threshold even when combined with pH3.0 vitamin C or pH9.0 soap-based cleansers.
Amsterdam clinic protocol reference: Step1 Pre-op pH test client’s skincare Step2 Monitor skin pH every 20min during procedure Step3 Post-op distribute lactobacillus extract stabilizer
2024 European Aesthetic Safety White Paper shows: clinics using this protocol reduced post-op sensitivity from 17% to 3.2%. Note: 0.5 pH difference impacts efficacy beyond 50%.
Animal-derived components
Beauty salon owner Emma encountered trouble in Hamburg: client developed quail egg-sized nodules on neck after injection with unpurified horse collagen filler. This caused loss of 3 VIP clients and €12,000 repair cost.
- Bovine hyaluronic acid: Munich lab gel electrophoresis detected 17% non-target protein in Korean supplier’s material (Case CA-112)
- Porcine elastin: Paris clinic mandates suppliers provide prion test reports
- Marine extracts: Norway’s salmon DNA repair factor extraction costs 8x synthetic versions
| Component type | Allergy rate | EU compliance |
|---|---|---|
| Animal-derived | 3.8% | need submit species traceability documents |
| Plant-based | 0.7% | pass microbial test |
Zurich beautician Lucas shares trick: UV light inspection shows unique fluorescence in genuine animal collagen. He identified synthetic-adulterated batch preventing class action.
International Cosmetic Safety Committee 2024 warning: avian-derived fillers require avian flu virus inactivation certification (Report IS-562-3)
Barcelona clinic’s solution: provide antihistamine emergency kit with each animal-derived filler containing epi-pen and cooling gel, reducing allergy disputes 76%.
Preservative system
California salon case CA-329 records client developing erythema after mixing paraben-containing skincare. Chaeum’s preservative system uses phenoxyethanol + ethylhexylglycerin combo certified by ICSC-045 maintaining 12-month sterility.
| Preservative type | Chaeum concentration | Traditional filler concentration | Irritation index |
|---|---|---|---|
| Phenoxyethanol | 0.8% | 1.2%-1.5% | ↓37% |
| Ethylhexylglycerin | 0.6% | not added | antimicrobial↑4x |
London dermatologist Maria states: “dual preservative system acts like smart gatekeeper” blocking microbes without damaging barrier. Cytotoxicity reduced 52% vs single preservatives.
- 【Emergency protocol】If abnormal burning occurs within 72h post-injection: ① Immediate ice compress ② Stop all glycolic acid/retinol products ③ Request emergency kit with Calmplex-5
Geneva lab tests show 98% preservative efficacy at 40°C. Compared to French brand’s methylisothiazolinone, Chaeum’s allergy rate dropped from 3.1% to 0.7%.
Warning: Munich case DE-445 shows post-op recovery extended 2.3x using formaldehyde-releasing preservatives
Storage note: keep opened products at 15-25°C, avoid mixing with metal ion serums. Zurich experts recommend vacuum pump bottles extending preservative efficacy to 18 months.
Allergy test protocol
Milan clinic incident: skipped allergy test caused facial edema. European practitioners now follow 3-level warning system:
- 48h prior patch test behind ear
- IgE antibody level test
- 0.02ml simulated injection on inner arm with 3mm micro-needle
| Test type | Chaeum protocol | Standard filler |
|---|---|---|
| Result time | 24h | 72h↑risk period |
| Allergen detection | 32 common triggers | only 5 basic items |
| False positive rate | 0.7% (2024 ICSC) | industry avg 6.2% |
Paris La Beaute Clinic requires clients submit 3-month hormone reports. Recent case: 32F showed delayed allergy to polysorbate 80 prevented by pre-test.
Note: Geneva University Hospital prohibits NSAIDs within 72h post-test to prevent symptom masking
Special case protocol: for clients with post-laser sensitivity (VISIA＞85), use subcutaneous impedance meter instead of needle test. Barcelona Dr.Ramon successfully treated rosacea patient’s urgent filler need this way.