Muchcaine PRO 5%

High-potency topical anesthetic emulsion (500g). Formulated for professional dermatological procedures requiring deep dermal analgesia. Utilizing an EMLA-standardized ratio of Lidocaine and Prilocaine for optimal safety and efficacy.

Formulation Data

API Classification: Amide-type Local Anesthetic

pH Range: 7.0 – 8.0 (Bio-compatible skin physiological pH)

Excipients: Carbomer 940, Polyoxyethylene Hydrogenated Castor Oil, Methylparaben (1.5mg/g).

Appearance: Stable White Oil-in-Water (O/W) Emulsion.

Performance Metrics

Onset of Action: 25 – 35 Minutes

Peak Analgesia: 60 Minutes post-application

Total Duration: 120 – 180 Minutes (occluded)

Penetration Depth: 3mm – 5mm

Pharmacodynamics

The synergistic combination of Lidocaine and Prilocaine functions by stabilizing the neuronal membrane. Both agents inhibit the ionic fluxes required for the initiation and conduction of impulses by blocking voltage-gated sodium channels. This dual-action approach ensures a lower melting point of the eutectic mixture, allowing for enhanced penetration of the stratum corneum compared to single-agent formulations.

Contraindications & Safety

Precautions: Do not apply to broken skin, eczematous areas, or mucous membranes. Use with caution in patients with G6PD deficiency or methemoglobinemia.

Storage: Store at controlled room temperature (15°C – 30°C). Avoid direct sunlight and extreme thermal fluctuations to maintain emulsion stability.

For professional use by licensed practitioners only. Conduct a 24-hour patch test prior to initial full-scale application.