Celosome Strong — High-Density HENM Filler for Deep Wrinkles & Facial Contouring

Celosome Strong is ExCoBio’s high-density variant — 24 mg/mL cross-linked HA + 0.3% lidocaine with the most pronounced HENM cross-linking in the standard Celosome range. Engineered for deep dermis and subcutaneous placement with 12–24 month durability. Targets deep wrinkles, cheek augmentation, jawline definition. KFDA registered.

Celosome Strong Hyaluronic Acid Filler is manufactured by ExCoBio Co. Ltd., a South Korea-based medical device and pharmaceutical company established in 2017. The product is part of the Celosome dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · GMP certified.

Celosome Strong Hyaluronic Acid Filler contains 24 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using ExCoBio Co. Ltd.’s HENM + 8-Phase Purification (High Density) technology. Phosphate-buffered saline at near-physiological pH carries the gel.

Per ExCoBio Co. Ltd.’s clinical data, Celosome Strong Hyaluronic Acid Filler delivers 12–24 months of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Deep dermis placement typically delivers the longer end of the duration range.

Celosome Strong Hyaluronic Acid Filler is engineered for deep dermis · subcutaneous placement. The standard recommended needle is 27G, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.

Celosome Strong Hyaluronic Acid Filler regulatory status: KFDA registered · GMP certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.

Store Celosome Strong Hyaluronic Acid Filler between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.

No. Celosome Strong Hyaluronic Acid Filler uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).

Yes — layered protocols combining different fillers are standard aesthetic practice. Celosome Strong Hyaluronic Acid Filler can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.

Both are high-density variants but differ in viscoelasticity. Celosome Strong (12–24 month durability) suits deep dermis to subcutaneous placement for cheek, jawline, and deep folds. Celosome Implant (12–24 month durability) is engineered specifically for deep subcutaneous to supraperiosteal layers for the most structural projection — typically chin augmentation, severe contouring, and significant facial sculpting. Practitioners select Strong for deep-dermal-to-subcutaneous correction and Implant for the deepest, most structural placements.