Side-By-Side
Chaeum Premium 4 HA Filler with Lidocaine vs Juvederm vs Restylane
| Feature |
Chaeum |
Juvederm (Allergan) |
Restylane (Galderma) |
| HA Concentration |
20 mg/mL |
15–24 mg/mL |
20 mg/mL |
| Cross-Linking Tech |
Monophasic |
Vycross / Hylacross |
NASHA® / OBT |
| Lidocaine |
0.3% (premixed) |
0.3% (XC lines) |
0.3% (Lidocaine variants) |
| Duration |
12–24 months |
6–24 months (varies) |
6–18 months (varies) |
| Origin |
South Korea (Hugel Pharma Co. Ltd.) |
USA (Allergan / AbbVie) |
Sweden (Galderma) |
| Established Since |
2001 |
2006 |
1996 |
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Comparison based on manufacturer published data. See our top dermal filler comparison guide for broader market context.
FAQs
Chaeum Premium 4 HA Filler with Lidocaine — Frequently Asked Questions
What is Chaeum Premium 4 HA Filler with Lidocaine?
Chaeum Premium 4 is Hugel Pharma’s highest-density variant — 20 mg/mL cross-linked HA + 0.3% lidocaine at maximum 4/4 cross-linking rate. Engineered for deep subcutaneous to supraperiosteal placement: cheek augmentation, chin projection, temple volumising, forehead contouring. 12–24 month durability. Supplied with 23G needles for deep tissue access.
Where is Chaeum Premium 4 HA Filler with Lidocaine manufactured?
Chaeum Premium 4 HA Filler with Lidocaine is manufactured by Hugel Pharma Co. Ltd., a South Korea-based medical device and pharmaceutical company established in 2001. The product is part of the Chaeum dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · GMP certified.
What is the HA concentration in Chaeum Premium 4 HA Filler with Lidocaine?
Chaeum Premium 4 HA Filler with Lidocaine contains 20 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using Hugel Pharma Co. Ltd.’s Monophasic Cross-Linking (4/4 Rate) technology. Phosphate-buffered saline at near-physiological pH carries the gel.
How long do Chaeum Premium 4 HA Filler with Lidocaine results last?
Per Hugel Pharma Co. Ltd.’s clinical data, Chaeum Premium 4 HA Filler with Lidocaine delivers 12–24 months of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Deep subcutaneous placement typically delivers the longer end of the duration range.
What is the recommended injection depth for Chaeum Premium 4 HA Filler with Lidocaine?
Chaeum Premium 4 HA Filler with Lidocaine is engineered for deep subcutaneous · supraperiosteal placement. The standard recommended needle is 23G, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.
Is Chaeum Premium 4 HA Filler with Lidocaine FDA approved or CE marked?
Chaeum Premium 4 HA Filler with Lidocaine regulatory status: KFDA registered · GMP certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.
How should Chaeum Premium 4 HA Filler with Lidocaine be stored at the clinic?
Store Chaeum Premium 4 HA Filler with Lidocaine between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.
Does Chaeum Premium 4 HA Filler with Lidocaine contain animal-derived ingredients?
No. Chaeum Premium 4 HA Filler with Lidocaine uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).
Can Chaeum Premium 4 HA Filler with Lidocaine be combined with other dermal fillers in the same session?
Yes — layered protocols combining different fillers are standard aesthetic practice. Chaeum Premium 4 HA Filler with Lidocaine can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.
Why does Chaeum Premium 4 have lower HA concentration (20 mg/mL) than Premium 1–3 (24 mg/mL)?
While counterintuitive, the lower HA concentration (20 mg/mL) in Premium 4 combined with the highest 4/4 cross-linking rate produces a denser, more rigid gel structure ideal for subcutaneous placement. The cross-linking process consumes some HA molecules in forming bonds, and at higher cross-link rates, lower starting HA concentrations can produce more structurally cohesive gels suited to deep placement. The 23G needle supplied with Premium 4 confirms its intended use in deep subcutaneous to supraperiosteal layers, where structural firmness matters more than HA volume density.
Important Safety Information
Read Before Clinical Use
Chaeum Premium 4 HA Filler with Lidocaine is a prescription medical device for use only by licensed aesthetic practitioners. Common reactions include injection-site bruising, swelling, redness, and tenderness — generally resolving within days. Deep placement (subcutaneous and supraperiosteal layers) involves heightened anatomical awareness of facial vasculature; practitioners require access to hyaluronidase for emergency dissolution. Like all hyaluronic acid dermal fillers, treatment carries rare but serious vascular complication risks. Contraindicated in patients with known hypersensitivity to hyaluronic acid or lidocaine, active skin infection at the treatment site, pregnancy, or breastfeeding. Full contraindications, vascular complication protocols, aftercare, and emergency guidance are detailed on the dermal filler safety page.
Read Full Dermal Filler Safety Information →
Chaeum is a registered trademark of Hugel Pharma Co. Ltd.. Fillersfairy.com is a channel distributor and does not provide medical advice. This page is for informational purposes only and does not replace the manufacturer’s official Instructions for Use, which remains the authoritative source for clinical administration. Regulatory status varies by jurisdiction — buyers are responsible for verifying legal status before ordering. Last reviewed May 2026 against Hugel Pharma Co. Ltd. manufacturer documentation.
Jessica M. –
I run a small clinic and needed to stock up on quality fillers. After comparing prices across multiple sites, fillersfairy had the best deals—especially with their bulk discounts. I ordered 20 units of Chaeum Premium 4 and saved nearly 8%. The ordering process was smooth, and the fillers arrived well-packaged and with a long shelf life, so no rush to use them all at once.
Benjamin –
LOVE the precision – the ultra-pure HA (99.95%) and smooth consistency let you place tiny amounts exactly where needed. Patients report feeling almost nothing thanks to the lidocaine. Noticeably less bruising compared to other products. You need technique – aspirating is non-negotiable, and over-injecting is easy if you’re heavy-handed.
Melissa Vance –
Finally found a filler that actually lasts in the tear troughs! I’ve used Chaeum Premium 4 for 8 months now. The high cross-linking really shows – results stay plump 15+ months in my patients. The lidocaine integration is genius; barely any discomfort during injection. Zero allergic reactions so far, and inflammation post-treatment is drastically reduced compared to other HA gels.