Quick Answer
Hyalace by BNC Global is a Korean dual-molecular-weight HA skinbooster — 64 mg total HA per 2 mL syringe, comprising 32 mg high-molecular-weight HA for surface hydration and structural support, plus 32 mg low-molecular-weight HA for deeper dermal penetration and biological signalling. Delivered via 5-point or 10-point superficial mesotherapy injection. Standard protocol is 2–3 sessions 4 weeks apart, with 6–9 month duration per course.
Why This Product Is Different
Hyalace’s dual-molecular-weight HA composition distinguishes it from single-MW HA boosters. High-MW HA (large molecules) sits in the upper dermis providing immediate hydration, mechanical support, and slow degradation. Low-MW HA (smaller molecules) penetrates more deeply and is more bioactive — engaging CD44 receptors to signal fibroblast proliferation and endogenous HA synthesis. The 1:1 ratio (32 mg + 32 mg) at 64 mg total concentration delivers both physical and signalling effects in a single product.
Mechanism of Action
Dual Molecular-Weight HA Biorevitalisation. High-MW HA (typically 1.0–2.0 MDa) and low-MW HA (typically 50–100 kDa) act through complementary pathways. High-MW HA binds water aggressively and creates a hydrated extracellular matrix scaffold — anti-inflammatory, mechanically supportive, slow-degrading. Low-MW HA fragments interact with CD44 receptors on fibroblasts and keratinocytes, triggering signalling cascades that include collagen synthesis, anti-apoptotic effects, and barrier protein expression. The combination delivers both immediate hydration and longer-term remodelling.
Compare Within Category
Within Fillersfairy’s HA Skinbooster category, Hyalace’s dual-MW approach is distinct. Compare with Hyaron (Dongkook, pure non-crosslinked HA), Revitrane HA20 (BR Pharm, monophasic crosslinked HA), and Puri Hilo PN (Aeterderm, HA + PN hybrid). Hyalace is the only pure dual-MW HA option in this lineup.
Frequently Asked Questions
What is Hyalace 2ml×1?
Hyalace 2ml×1 is a Korean dual-molecular-weight HA skinbooster from BNC Global. A single 2 mL pre-filled syringe contains 64 mg total hyaluronic acid: 32 mg high-MW HA combined with 32 mg low-MW HA. The dual-MW composition delivers both surface hydration via high-MW HA and deeper dermal effect via low-MW HA.
What does ‘dual molecular weight’ mean and why does it matter?
Hyaluronic acid molecules vary in chain length, expressed as molecular weight (MW). High-MW HA (typically over 1 MDa) consists of long chains that stay in place and bind large amounts of water — good for surface hydration and structural matrix support. Low-MW HA (typically below 100 kDa) consists of shorter fragments that penetrate deeper, engage CD44 receptors, and trigger cell signalling — good for biological remodelling. Hyalace combines both in 1:1 ratio for complementary effect.
How is Hyalace different from Hyaron?
Both are non-crosslinked HA skinboosters but with different formulations. Hyaron (Dongkook Pharmaceutical, on market since 1987) contains pure sodium hyaluronate without specified MW separation — 25 mg per 2.5 mL non-crosslinked. Hyalace (BNC Global) specifies its dual-MW formulation: 32 mg high-MW HA + 32 mg low-MW HA per 2 mL. Hyalace’s dual-MW approach is its key marketing differentiator.
How is Hyalace injected?
Two main techniques. (1) 5-point technique: five strategic deposits per facial zone for efficient coverage with minimal injection trauma. (2) 10-point pattern: more granular distribution across larger zones. Use 29G or 30G fine needle. Inject 0.2–0.4 mL per point in the superficial dermis. The product disperses within roughly 2 cm of each injection point, so 10 well-placed points typically cover the full face.
How many sessions do I need?
Standard protocol is 2–3 sessions spaced 4 weeks apart. Single-syringe boxes give flexibility to add sessions individually. Visible improvement typically appears within 7–10 days; full effect by the third session. Duration after the complete course is 6–9 months. Maintenance is one session every 6–12 months based on individual response.
Does Hyalace contain lidocaine?
No — Hyalace 2ml×1 is supplied as a pure HA formulation without lidocaine. For patients sensitive to injection pain, apply topical anaesthetic cream 30 minutes before procedure, or consider ice pre-application. The 5-point or 10-point injection technique with fine 29G–30G needles minimises discomfort compared to multi-point traditional mesotherapy patterns.
Where can Hyalace be used?
Face (forehead, cheeks, perioral), neck, and décolletage. Avoid: active acne or infection at site, periorbital area within 5 mm of orbital rim, lip vermillion border (higher-precision products preferred). Suitable for combination with same-session microneedling for layered effect, but spacing with cross-linked filler placement by 4 weeks is advised.
Are there contraindications or precautions?
Standard HA contraindications: pregnancy and lactation, active skin infection at injection site, known HA hypersensitivity, autoimmune disease in active flare, recent anticoagulant therapy. Allergy testing not generally required for non-animal HA. Have hyaluronidase available for vascular incident management even with non-crosslinked HA.
Where is Hyalace manufactured?
Manufactured by BNC Global, a Seoul-based Korean pharmaceutical company founded in 2018. Hyalace is part of the broader BNC Global aesthetic product line, alongside Hanheal Exosome and Elaxen PN.
How much does Hyalace 2ml×1 cost?
Hyalace 2ml×1 is priced at USD $32.00 per single 2 mL syringe on Fillersfairy, with wholesale pricing for licensed practitioners. Multi-syringe ordering for bulk practice supply is supported.
Naomi L –
Running a medspa means every dollar counts. Fillersfairy’s 10-vial deal saved me $29 compared to our old supplier. Hyalace’s hydration effect lasts noticeably longer clients keep rebooking. The portal’s real-time inventory tracker is a lifesaver when we’re running low.
Marcus T –
Was skeptical about buying dermal fillers online, but fillersfairy’s certification badges convinced me. Ordered 5 Hyalace vials, noticed my skin looked plumper after the first session, and the injection points healed faster than with other brands.