5 mg/ml PDRN

Polydeoxyribonucleotide

Extracted from salmon milt. Upregulates VEGF (Vascular Endothelial Growth Factor), stimulating angiogenesis and accelerating physiological DNA synthesis in damaged dermal layers.

20 mg/ml HA

Hyaluronic Acid (1500 kDa)

High molecular weight, non-cross-linked structure. Restores extracellular matrix hydration, providing a volumetric structural scaffold for continuous 8-hour cellular moisture retention.

1 mg/ml Niacinamide

Stabilized Vitamin B3

Inhibits melanosome transfer to keratinocytes. Clinically proven to reduce transepidermal water loss (TEWL) and stabilize the epidermal lipid barrier function.

Citation: Journal of Cosmetic Dermatology (2022); 21(3): 145-152. “Efficacy of combined PDRN and non-cross-linked HA in facial rejuvenation.”

+ 72.4%

Stratum Corneum Hydration Retention (Week 4)

– 46.8%

Periorbital Rhytid Depth Reduction (Week 12)

+ 31.2%

Dermal Density Increase via Ultrasound (Week 12)

Injection Parameters

Depth: Superficial to mid-dermis (1.0mm – 2.0mm)

Gauge: 30G or 32G (4mm)

Technique: Micro-papule or Nappage

Dosage: 0.05ml per injection point

Treatment Schedule

Initial Course: 3 to 4 sessions

Interval: 14 days between sessions

Maintenance: 1 session every 3 to 6 months

Storage & Handling

Volume: 3 x 2.2ml per box

Temperature: 1°C to 30°C

Constraint: UV-sensitive. Do not freeze.