Quick Answer
ASCE+ IRLV Intimate Care for Women by ExoCoBio is a Korean plant-derived exosome kit specifically formulated for intimate area rejuvenation — 20 mg lyophilized Rosa damascena callus exosomes (via ExoSCRT™ technology) plus a 2.5 mL activator containing hyaluronic acid, retinol, and vitamin C. The plant-origin vegan exosome platform delivers signalling cargo to vulvar and intimate skin for hydration, elasticity, and tissue regeneration. Course is typically 3–5 sessions every 2–4 weeks.
Why This Product Is Different
ASCE+ IRLV is one of the few exosome products specifically formulated for intimate care, distinct from ExoCoBio’s facial line (ASCE+ SRLV, ASCE+ HRLV, etc.). The plant-derived Rosa damascena callus exosome platform offers a vegan, non-animal alternative to mammalian-cell exosomes — important for some patient demographics. The activator contains hyaluronic acid for immediate hydration, retinol for cellular turnover, and vitamin C for antioxidant and brightening effect — a multi-active complement to the exosome signalling cargo. ExoCoBio’s ExoSCRT™ technology is the platform behind this product family.
Mechanism of Action
Plant Exosome Signalling for Intimate Tissue Regeneration. Rosa damascena callus-derived exosomes (30–150 nm extracellular vesicles) carry plant microRNAs, peptides, growth factors, and signalling lipids. Once delivered to intimate skin via topical, mesotherapy, or post-procedure application, the exosomes are taken up by local fibroblasts and epithelial cells, releasing their cargo into the cytoplasm. Downstream effects include fibroblast proliferation, collagen synthesis, anti-inflammatory cytokine modulation, and enhanced barrier function — all relevant for intimate skin atrophy and dryness.
Compare Within Category
ASCE+ IRLV is currently the only product in Fillersfairy’s Intimate Rejuvenation Exosome subcategory. Within ExoCoBio’s broader ASCE+ portfolio: SRLV (facial), HRLV (hair / scalp), and IRLV (intimate) share the same ExoSCRT™ platform but with different activator compositions tuned for each anatomical site. Compare with traditional intimate rejuvenation approaches: laser-only (CO2 fractional, Er:YAG) or radiofrequency-only protocols, where ASCE+ IRLV serves as a regenerative adjunct.
Frequently Asked Questions
What is ASCE+ IRLV Intimate Care for Women?
ASCE+ IRLV is a Korean plant-derived exosome kit from ExoCoBio specifically formulated for intimate area rejuvenation. It contains 20 mg lyophilized exosomes from Rosa damascena (rose) callus stem cells, plus a 2.5 mL activator with hyaluronic acid, retinol, and vitamin C. The IRLV variant (Intimate Rejuvenation Line — Vulvar) shares the ExoSCRT™ exosome platform with ExoCoBio’s facial and hair products but is formulated for intimate skin.
Are the exosomes plant-derived or stem cell-derived?
Plant-derived. Rosa damascena (rose) callus tissue is cultured, and extracellular vesicles (exosomes) are extracted from the callus cell culture via ExoCoBio’s ExoSCRT™ technology. This is a vegan, non-animal exosome source — distinct from mammalian cell line exosomes (mesenchymal stem cell, fibroblast, etc.). The plant-origin platform is important for patient demographics requiring vegan products or those concerned about animal-cell sources.
How is ASCE+ IRLV different from ASCE Plus+ SRLV (facial)?
Both share the ExoSCRT™ Rosa damascena callus exosome platform, but the activator and indication differ. SRLV (facial) activator is formulated for facial skin — different growth factor and active ingredient ratios. IRLV activator includes retinol and vitamin C alongside HA for intimate skin physiology. The 20 mg lyophilized exosome content is comparable; the application protocol differs significantly.
Is ASCE+ IRLV FDA-approved for vaginal use?
No. ASCE+ IRLV is not FDA-approved for any medical vaginal or intimate indication. It is positioned as a cosmeceutical / aesthetic product within ExoCoBio’s intimate care line. Use is restricted to licensed healthcare professionals operating within their jurisdiction’s regulatory framework. Practitioners should consult local regulations before clinical use for intimate indications.
How is ASCE+ IRLV reconstituted and applied?
Open the lyophilized exosome vial (20 mg dry powder) and the activator vial (2.5 mL liquid). Transfer the activator into the exosome vial. Gently agitate (do not shake) until fully dissolved. Apply via one of: (1) topical post-procedure (post-laser intimate rejuvenation, post-RF, post-microneedling) within 30 minutes, (2) superficial mesotherapy with 30G–32G needle, or (3) practitioner-specific protocols. Use immediately after reconstitution.
How many sessions are recommended?
Typical course is 3–5 sessions spaced 2–4 weeks apart. The exact protocol depends on indication and practitioner preference. Maintenance is one session every 3–6 months based on individual response. ASCE+ IRLV is often used as an adjunct to laser or radiofrequency intimate rejuvenation protocols rather than as standalone therapy.
What indications does ASCE+ IRLV address?
Primarily intimate skin atrophy and dryness associated with hormonal changes (postmenopausal, postpartum, lactational), mild elasticity loss, and post-procedure recovery for intimate rejuvenation interventions. Not indicated for clinically diagnosed vaginal atrophy requiring hormonal therapy, infection, malignancy, or any condition requiring medical management — these require medical evaluation.
Are there contraindications?
Absolute: active intimate infection (bacterial, fungal, viral), pregnancy, lactation, known hypersensitivity to any kit component (rose extract, retinol, ascorbic acid). Relative: active intimate dermatitis, recent intimate surgery (within 4–6 weeks), bleeding disorders, anticoagulant therapy without medical clearance, immunosuppression. Patients should be evaluated by a qualified practitioner before use.
Where is ASCE+ IRLV manufactured?
Manufactured by ExoCoBio Inc., a Korean biotechnology company specialising in exosome-based regenerative aesthetics. ExoCoBio’s ExoSCRT™ technology is the platform behind the ASCE+ product family (SRLV facial / HRLV hair / IRLV intimate). The company is headquartered in Korea and operates internationally.
How much does ASCE+ IRLV cost?
ASCE+ IRLV Intimate Care for Women is priced at USD $118.00 per kit on Fillersfairy, with wholesale pricing for licensed practitioners. Each kit is one reconstituted session.
Sophia M. –
Seriously, within 30 minutes of injection, I felt the lumps shrinking. Liporase is by far the strongest enzyme I’ve used. I previously bought a cheap version that required two rounds and left my skin red. This Liporase fixed everything in one go. While 10 vials might seem like a lot, given the results and shelf life, it’s absolutely worth it.