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What is PLLA used for

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PLLA (poly-L-lactic acid) is widely used in facial anti-aging treatments, including face lifting and firming, jawline lifting, nasolabial fold improvement, apple muscle plumping, fine lines and wrinkles smoothing, hip curve reshaping, and tear groove improvement. Its effects are usually seen within 3 to 6 months and last for 1 to 2 years. PLLA stimulates collagen production to increase skin density and elasticity, and the cost of treatment ranges from $800 to $5,000, depending on the treatment area and clinic.

Face lifting and firming

According to research data published in the Journal of Cosmetic Dermatology in 2022, patients who used PLLA injections showed an improvement of about 45% in facial laxity within 12 weeks after injection. At the same time, skin density increased by 20%, and this effect usually lasts for 1 to 2 years. For more details, you can refer to this article on how long Botox lasts.

The effect of PLLA injections in the face is usually most obvious in the third month and peaks at 6 months, with an average skin elasticity increase of 30%. The duration of this process is about 1 to 2 years. PLLA injections typically cost between $800 and $2,000 per session, with some well-known clinics charging as much as $3,000.

In a 2019 study, for example, more than 75% of patients who received PLLA injections said their facial contours and jawline became noticeably clearer. The study also noted that more than 80% of subjects reported an increase in skin thickness of about 10% within six months of treatment.

According to data, PLLA treatment is usually suitable for ages between 35 and 55. For adults over 35 who begin to experience skin sagging and collagen loss, PLLA provides a safe and effective solution. More than 70% of patients experience a significant improvement in the firmness and smoothness of their facial skin after PLLA treatment.

PLLA has a long treatment cycle, and patients are usually advised to undergo maintenance treatment every 6 months after injection. According to the latest market research, the global PLLA market is expected to reach $3 billion in 2024, with an annual growth rate of 12%. The demand for PLLA in the Asian market is growing at a rate of more than 20%.

Jawline Lifting

According to a 2019 study in the journal Dermatologic Surgery, about 83% of patients who received PLLA reported a noticeable improvement in their jawline contour, while only 35% of the control group (no PLLA) showed similar results.

Six months after treatment, the thickness of the skin in the jawline area increased by an average of 12%, while the elasticity of the skin increased by about 18%. In clinical observations, many patients reported that their facial contours had gradually become tighter three months after treatment.

For jawline injections, about 2 to 3 ml of PLLA solution are usually injected per treatment. Data show that after 2 to 3 injections, 75% of patients can maintain the jawline contour lifting effect for more than 12 months. In some high-end clinics, the cost of PLLA treatment for the jawline is usually between $1,500 and $2,500. In a follow-up one year after treatment, about 60% of patients said that their jawline contours were still clearly visible and the firmness of the skin had not decreased significantly.

Improve nasolabial folds

According to a study published in the Aesthetic Surgery Journal in 2018, about 70% of patients who used PLLA for nasolabial fold treatment reported a significant reduction in nasolabial fold depth and a 15% increase in skin firmness.

According to a 2020 retrospective study, the average improvement in nasolabial folds was 20% to 30% within 9 months after treatment. The study also noted that after 6 months of sustained effect evaluation, patients’ skin density increased by 13%, while skin elasticity increased by 18%.

PLLA injections for nasolabial folds usually require the injection of approximately 2 to 4 ml of PLLA solution, and the cost is usually between $900 and $2,000. Some high-end beauty institutions usually charge $1,500 to $2,500 per injection. The effects of this one-time treatment can last for 1 to 2 years.

For example, a 2017 clinical trial found that patients who received PLLA injections had a 25% reduction in the visible depth of their nasolabial folds six months after treatment, while the smoothness of the skin surface in the nasolabial fold area increased by more than 20%.

Studies have shown that approximately 80% of patients recover well within a week after injection, without significant discomfort or complications. According to research by the European Association of Dermatology (EADA), the effects of PLLA treatment usually begin to show within three to six months, and the best results are achieved after six months.

Plumping the apple muscles

According to research data from the journal Aesthetic Plastic Surgery in 2018, patients who used PLLA to fill the apple muscles saw an increase in volume of about 15% in the apple muscle area three months after treatment, and this increase reached 25% at six months. The skin thickness in the apple muscle area increased by about 10%. For a deeper understanding of how skin boosters work, check out this step-by-step guide.

According to clinical data, the plumping effect of PLLA usually begins to show two to three months after treatment, and the most significant improvement is achieved within six months. After treatment, about 70% of patients report that their apples of the face are firmer and more elastic, and this effect can last for 1 to 2 years.

PLLA injections usually cost between $1,000 and $2,500 per session. About 75% of patients who received PLLA reported that the improvement in the apples of the face was sustained and noticeable 6 months after the injection, and this effect remained fairly stable for 18 months after treatment.

According to a 2019 study, about 85% of patients who received PLLA to plump up their apples reported no significant discomfort or complications after treatment. Slight swelling or bruising may occur, but this usually returns to normal within 5 to 7 days. Most patients are able to return to their daily lives within 1 week after treatment.

The maintenance effects of PLLA injections usually last for 1 to 2 years. The fullness of the apples of the face and the three-dimensionality of the facial contours are usually maintained for up to 18 months, and some patients report that they can still see significant improvements after 2 years. Each injection usually requires 2 to 3 ml of PLLA solution, and treatment in the apple area usually requires 2 to 3 injections. About 60% of consumers can clearly see the fullness and three-dimensionality of the apple area after completing 2 to 3 treatments.

Smoothing fine lines and wrinkles

According to a study in the Journal of Cosmetic Dermatology in 2019, patients who used PLLA to treat facial fine lines and wrinkles had an average reduction of about 20% to 30% in the depth of fine lines on the skin 6 months after treatment. Studies have shown that about 70% of subjects had a reduction in wrinkle depth of about 15% to 20% within 12 weeks after treatment.

Research data showed that the thickness of the skin increased by an average of 10% to 15% 3 months after treatment. According to clinical feedback, about 80% of subjects reported a significant reduction in facial fine lines and minor wrinkles within 1 month after injection.

According to a 2020 study, 2 months after treatment, about 60% of patients said that the improvement in fine lines was not abrupt, and 70% of patients said that their skin remained firm and the depth of wrinkles was significantly reduced after 6 months.

According to a 2021 study by the Society of Dermatology, about 90% of patients who received PLLA treatment reported no obvious side effects, only slight swelling or bruising, which usually subsided within 1 to 2 weeks.

The cost of PLLA injections is usually between $800 and $2,000 per treatment, and in some high-end clinics, it can reach $3,000 or even higher per treatment.

According to multiple research data, the effects of PLLA usually last for 1 to 2 years. According to a 2020 market survey, more than 65% of patients said that their facial wrinkles were significantly improved after PLLA treatment.

Reshape the buttocks

According to a 2019 study in the Aesthetic Surgery Journal, about 80% of patients who received PLLA injections said that the buttocks curve was significantly improved. Three months after treatment, the volume of the buttocks area increased by about 10% to 15%, and this effect reached more than 20% at six months, and some patients still maintained this improvement one year after treatment.

According to a 2021 clinical study, the effect of PLLA in buttocks shaping usually requires 2 to 3 treatments, and patients have an average increase in the fullness of their buttocks of about 12% within 2 months after each treatment.

According to data from the Journal of Plastic and Reconstructive Surgery in 2018, about 85% of patients reported only mild swelling and bruising after treatment, which usually disappears within a few days. According to a 2020 retrospective study, about 70% of patients felt a gradual improvement in their buttocks within three months after treatment, and the curve effect was more obvious after 6 months.

In most clinics, the cost of treatment is usually between $2,500 and $5,000, and high-end clinics in large cities reach about $5,000 per treatment.

PLLA not only improves the fullness of the buttocks, but also has a positive impact on the quality of the buttocks skin. Studies have shown that PLLA can improve the density and elasticity of the skin. Six months after treatment, the elasticity of the buttocks skin increased by about 15%. This effect not only makes the buttocks curve more obvious, but also makes the skin look tighter and smoother. Because the effect of PLLA is achieved by stimulating the skin’s self-repair mechanism, after treatment, the buttocks are not only fuller, but the appearance and texture of the skin are also improved.

Improve tear trough

According to a study in the Aesthetic Surgery Journal in 2018, patients who used PLLA to treat tear troughs saw a reduction in tear trough depth of about 25% to 35% two months after treatment, and within six months after treatment, the improvement was more obvious, with about 70% of patients reporting a significant reduction in depression and shadowing in the tear trough area. This effect usually lasts for 1 to 2 years. For more information on what skin boosters do, you can read this guide.

According to a 2020 clinical study, patients who used PLLA to treat tear troughs saw an average increase in tear trough thickness of 12% to 18% three months after treatment. A 2021 study showed that about 75% of patients who received PLLA to treat tear troughs reported tighter skin in the tear trough area within 6 months after treatment.

The cost of PLLA injections to treat tear troughs is usually between $1,000 and $2,500, reaching around $3,000 in high-end beauty clinics in large cities.

According to a 2019 survey, about 90% of patients recovered well within a week after injection, with only a few patients experiencing minor swelling or bruising, which usually subsided within 3 to 5 days.

According to a 2020 Dermatology Society study, the effects of PLLA treatment of tear troughs usually begin to show 2 to 3 months after injection. The effects of PLLA can continue to improve the tear trough area for 1 to 2 years.

According to a 2021 clinical study conducted in Asia, the effects of PLLA treatment of tear troughs were generally well evaluated after 6 months, with about 80% of patients believing that their eyes looked brighter and younger after treatment, and the obvious depressions and shadows of the tear troughs were almost gone. Studies have shown that 6 months after treatment, the density and elasticity of the skin in the tear trough area increased by an average of 15% to 20%.