E.P.T.Q. Dermal Filler — ZEEP-Technology HA Filler in S100, S300 & S500

E.P.T.Q. is Jetema’s flagship monophasic HA filler collection — 24 mg/mL cross-linked hyaluronic acid + 0.3% lidocaine, produced via patented ZEEP (Zero Endotoxin and BDDE Entire Process) and HIVE-structure technology. Three variants — S100 (30 Pa, superficial), S300 (mid-range), and S500 (500 Pa, deep contouring) — share the same base formulation differentiated by viscoelasticity. Endotoxin under 0.1 EU/mL, BDDE residue undetectable.

E.P.T.Q. Dermal Filler Collection (S100 / S300 / S500) is manufactured by Jetema Co. Ltd., a South Korea-based medical device and pharmaceutical company established in 1994. The product is part of the E.P.T.Q. dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · CE marked · GMP certified.

E.P.T.Q. Dermal Filler Collection (S100 / S300 / S500) contains 24 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using Jetema Co. Ltd.’s ZEEP (Zero Endotoxin and BDDE Entire Process) + HIVE-Structure technology. Phosphate-buffered saline at near-physiological pH carries the gel.

Per Jetema Co. Ltd.’s clinical data, E.P.T.Q. Dermal Filler Collection (S100 / S300 / S500) delivers 9-18 months (varies by variant) of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Superficial dermis (s100) placement typically delivers the longer end of the duration range.

E.P.T.Q. Dermal Filler Collection (S100 / S300 / S500) is engineered for superficial dermis (s100) · mid-deep dermis (s300) · subcutaneous (s500) placement. The standard recommended needle is 27G (varies by variant), supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.

E.P.T.Q. Dermal Filler Collection (S100 / S300 / S500) regulatory status: KFDA registered · CE marked · GMP certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.

Store E.P.T.Q. Dermal Filler Collection (S100 / S300 / S500) between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.

No. E.P.T.Q. Dermal Filler Collection (S100 / S300 / S500) uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).

Yes — layered protocols combining different fillers are standard aesthetic practice. E.P.T.Q. Dermal Filler Collection (S100 / S300 / S500) can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.

ZEEP (Zero Endotoxin and BDDE Entire Process) is Jetema’s proprietary manufacturing process eliminating endotoxin and BDDE residue throughout production — keeping endotoxin under 0.1 EU/mL and BDDE undetectable. Combined with HIVE-structure cross-linking, this lets Jetema produce three viscoelasticity grades from one base formulation. Variant selection: S100 (30 Pa) for superficial fine lines and periorbital; S300 (mid range) for moderate nasolabial folds, lip augmentation, marionette lines; S500 (500 Pa) for deep subcutaneous cheek augmentation, chin, jawline, non-surgical rhinoplasty. Practitioners often combine variants (S500 deep + S300 mid + S100 surface) for full-face protocols.