Chaeum Premium 3 — Monophasic HA Filler for Deep Wrinkles & Facial Volume (3/4)
Chaeum Premium 3 is Hugel Pharma’s high-density monophasic HA filler — 24 mg/mL cross-linked HA + 0.3% lidocaine at 3/4 cross-linking rate. Engineered for mid-to-deep dermal placement targeting deep wrinkles, lip augmentation, and facial volumising. 12–18 month durability. Supplied as 2 × 1.1 mL syringes + 4 × 25G needles per box.
Manufacturer: Hugel Pharma Co. Ltd., South Korea · Established 2001
How Chaeum Premium 3 Hyaluronic Acid Filler Is Engineered
Monophasic Cross-Linking (3/4 Rate)
Hugel Pharma Co. Ltd.’s proprietary cross-linking process produces a stabilised HA gel matrix engineered for sustained tissue retention. The technology balances viscoelasticity (firmness for projection) with extrusion smoothness (easier injection through the 25G needle). The result: predictable handling, consistent gel distribution, and 12–18 months durability in mid to deep dermis placement.
Quality & Purity
Non-animal hyaluronic acid produced by bacterial fermentation. Endotoxin levels controlled below international safety thresholds. Stringent manufacturing under GMP-certified conditions minimises BDDE residue, heavy metals, and protein contaminants — reducing the risk of post-injection inflammation, granuloma formation, or hypersensitivity reactions in suitable patient profiles.
Chaeum Premium 3 Hyaluronic Acid Filler Active Ingredients
Cross-Linked Hyaluronic Acid
Non-animal hyaluronic acid produced by bacterial fermentation, cross-linked using Hugel Pharma Co. Ltd.’s Monophasic Cross-Linking (3/4 Rate) technology. The cross-linking process creates a stable, durable gel matrix that resists rapid enzymatic breakdown in tissue. Phosphate-buffered saline carries the gel at near-physiological pH.
Lidocaine HCl
Premixed local anaesthetic at the industry-standard 0.3% concentration. Reduces injection-site discomfort and eliminates the need for on-site mixing with separate lidocaine vials. The lidocaine itself wears off within hours of injection and does not affect long-term gel duration.
Where Chaeum Premium 3 Hyaluronic Acid Filler Is Used
Deep Nasolabial Folds
Pronounced nose-to-mouth folds requiring structural fill. Mid-to-deep dermal placement using the 25G needle.
Lip Augmentation
Significant lip body volumising. The 3/4 cross-link rate delivers sustained shape over 12–18 months.
Cheek & Midface Volumising
Cheekbone and midface volume restoration. Deep dermal placement for sustained projection.
Forehead Volumising
Off-label use for age-related forehead volume loss. The high cross-link rate supports structural fill.
Chaeum Premium 3 Hyaluronic Acid Filler vs Juvederm vs Restylane
| Feature | Chaeum | Juvederm (Allergan) | Restylane (Galderma) |
|---|---|---|---|
| HA Concentration | 24 mg/mL | 15–24 mg/mL | 20 mg/mL |
| Cross-Linking Tech | Monophasic | Vycross / Hylacross | NASHA® / OBT |
| Lidocaine | 0.3% (premixed) | 0.3% (XC lines) | 0.3% (Lidocaine variants) |
| Duration | 12–18 months | 6–24 months (varies) | 6–18 months (varies) |
| Origin | South Korea (Hugel Pharma Co. Ltd.) | USA (Allergan / AbbVie) | Sweden (Galderma) |
| Established Since | 2001 | 2006 | 1996 |
↔ Swipe horizontally on mobile to view all columns
Comparison based on manufacturer published data. See our top dermal filler comparison guide for broader market context.
Chaeum Premium 3 Hyaluronic Acid Filler Product Specifications
Manufacturer
- Brand: Chaeum
- Company: Hugel Pharma Co. Ltd.
- Country: South Korea
- Established: 2001
Formula
- HA Source: Non-animal bacterial fermentation
- HA Concentration: 24 mg/mL
- Lidocaine: 0.3% (3 mg/mL) premixed
- Cross-linking: Monophasic Cross-Linking (3/4 Rate)
Performance
- Duration: 12–18 months
- Injection Depth: Mid to deep dermis
- Recommended Needle: 25G
- Last Reviewed: May 2026
Approval & Storage
- Approvals: KFDA registered · GMP certified
- Packaging: 2 × 1.1 mL pre-filled syringes + 4 × 25G needles
- Storage: 2–25 °C, do not freeze
- Shelf life: 24 months unopened
Verify regulatory status at the official Korean MFDS database — nedrug.mfds.go.kr. For market pricing context, see our dermal filler pricing guide.
Chaeum Premium 3 Hyaluronic Acid Filler — Frequently Asked Questions
What is Chaeum Premium 3 Hyaluronic Acid Filler?
Chaeum Premium 3 is Hugel Pharma’s high-density monophasic HA filler — 24 mg/mL cross-linked HA + 0.3% lidocaine at 3/4 cross-linking rate. Engineered for mid-to-deep dermal placement targeting deep wrinkles, lip augmentation, and facial volumising. 12–18 month durability. Supplied as 2 × 1.1 mL syringes + 4 × 25G needles per box.
Where is Chaeum Premium 3 Hyaluronic Acid Filler manufactured?
Chaeum Premium 3 Hyaluronic Acid Filler is manufactured by Hugel Pharma Co. Ltd., a South Korea-based medical device and pharmaceutical company established in 2001. The product is part of the Chaeum dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · GMP certified.
What is the HA concentration in Chaeum Premium 3 Hyaluronic Acid Filler?
Chaeum Premium 3 Hyaluronic Acid Filler contains 24 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using Hugel Pharma Co. Ltd.’s Monophasic Cross-Linking (3/4 Rate) technology. Phosphate-buffered saline at near-physiological pH carries the gel.
How long do Chaeum Premium 3 Hyaluronic Acid Filler results last?
Per Hugel Pharma Co. Ltd.’s clinical data, Chaeum Premium 3 Hyaluronic Acid Filler delivers 12–18 months of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Mid to deep dermis placement typically delivers the longer end of the duration range.
What is the recommended injection depth for Chaeum Premium 3 Hyaluronic Acid Filler?
Chaeum Premium 3 Hyaluronic Acid Filler is engineered for mid to deep dermis placement. The standard recommended needle is 25G, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.
Is Chaeum Premium 3 Hyaluronic Acid Filler FDA approved or CE marked?
Chaeum Premium 3 Hyaluronic Acid Filler regulatory status: KFDA registered · GMP certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.
How should Chaeum Premium 3 Hyaluronic Acid Filler be stored at the clinic?
Store Chaeum Premium 3 Hyaluronic Acid Filler between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.
Does Chaeum Premium 3 Hyaluronic Acid Filler contain animal-derived ingredients?
No. Chaeum Premium 3 Hyaluronic Acid Filler uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).
Can Chaeum Premium 3 Hyaluronic Acid Filler be combined with other dermal fillers in the same session?
Yes — layered protocols combining different fillers are standard aesthetic practice. Chaeum Premium 3 Hyaluronic Acid Filler can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.
Is Chaeum Premium 3 suitable for cheek augmentation?
Chaeum Premium 3 is suitable for moderate cheek volumising at the mid-to-deep dermal layer. For deeper subcutaneous and supraperiosteal cheek augmentation requiring more pronounced projection, Chaeum Premium 4 is the dedicated variant (4/4 cross-link rate, 23G needle, 20 mg/mL HA concentration). Practitioners often layer Premium 3 in deeper dermis and Premium 4 in subcutaneous for combined midface lift protocols.
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Browse category →Read Before Clinical Use
Chaeum Premium 3 Hyaluronic Acid Filler is a prescription medical device for use only by licensed aesthetic practitioners. Common reactions include injection-site bruising, swelling, redness, and tenderness — generally resolving within days. Like all hyaluronic acid dermal fillers, treatment carries rare but serious vascular complication risks. Contraindicated in patients with known hypersensitivity to hyaluronic acid or lidocaine, active skin infection at the treatment site, pregnancy, or breastfeeding. Full contraindications, vascular complication protocols, aftercare, and emergency guidance are detailed on the dermal filler safety page.
Read Full Dermal Filler Safety Information →Chaeum is a registered trademark of Hugel Pharma Co. Ltd.. Fillersfairy.com is a channel distributor and does not provide medical advice. This page is for informational purposes only and does not replace the manufacturer’s official Instructions for Use, which remains the authoritative source for clinical administration. Regulatory status varies by jurisdiction — buyers are responsible for verifying legal status before ordering. Last reviewed May 2026 against Hugel Pharma Co. Ltd. manufacturer documentation.


Mark Foster –
Having used Chaeum Premium 3 from fillersfairy in my practice, the flow of the gel is smooth and the inclusion of lidocaine makes a noticeable difference in patient comfort. The results we’re achieving are very natural-looking, which is exactly what we aim for. The product performs as expected, and the fact that it comes from a reliable source like fillersfairy gives me added confidence in its quality.
Jessica Tomson –
I placed a bulk order for 20 boxes of Chaeum Premium 3 on fillersfairy for my clinic. The discount for ordering that quantity was significant, which really helps with our operational costs. I compared several suppliers, and fillersfairy’s pricing was genuinely competitive without making me doubt the product’s authenticity.