Side-By-Side
Neuramis Volume Lidocaine Dermal Filler vs Juvederm vs Restylane
| Feature |
Neuramis |
Juvederm (Allergan) |
Restylane (Galderma) |
| HA Concentration |
20 mg/mL |
15–24 mg/mL |
20 mg/mL |
| Cross-Linking Tech |
SHAPE |
Vycross / Hylacross |
NASHA® / OBT |
| Lidocaine |
0.3% (premixed) |
0.3% (XC lines) |
0.3% (Lidocaine variants) |
| Duration |
Up to 12 months |
6–24 months (varies) |
6–18 months (varies) |
| Origin |
South Korea (Medytox Inc.) |
USA (Allergan / AbbVie) |
Sweden (Galderma) |
| Established Since |
2000 |
2006 |
1996 |
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Comparison based on manufacturer published data. See our top dermal filler comparison guide for broader market context.
FAQs
Neuramis Volume Lidocaine Dermal Filler — Frequently Asked Questions
What is Neuramis Volume Lidocaine Dermal Filler?
Neuramis Volume Lidocaine is Medytox’s highest-density variant — 20 mg/mL cross-linked HA + 0.3% lidocaine with the most pronounced SHAPE cross-linking in the standard Neuramis range. Engineered for deep dermal to subcutaneous placement: facial contouring, cheek augmentation, chin projection, and structural volume restoration. Up to 12 months durability with outstanding cohesiveness.
Where is Neuramis Volume Lidocaine Dermal Filler manufactured?
Neuramis Volume Lidocaine Dermal Filler is manufactured by Medytox Inc., a South Korea-based medical device and pharmaceutical company established in 2000. The product is part of the Neuramis dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · CE marked · FDA DMF · ISO 13485 · EDQM certified.
What is the HA concentration in Neuramis Volume Lidocaine Dermal Filler?
Neuramis Volume Lidocaine Dermal Filler contains 20 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using Medytox Inc.’s SHAPE Technology (Highest Viscoelasticity) technology. Phosphate-buffered saline at near-physiological pH carries the gel.
How long do Neuramis Volume Lidocaine Dermal Filler results last?
Per Medytox Inc.’s clinical data, Neuramis Volume Lidocaine Dermal Filler delivers Up to 12 months of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Deep dermis placement typically delivers the longer end of the duration range.
What is the recommended injection depth for Neuramis Volume Lidocaine Dermal Filler?
Neuramis Volume Lidocaine Dermal Filler is engineered for deep dermis · subcutaneous placement. The standard recommended needle is 27G, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.
Is Neuramis Volume Lidocaine Dermal Filler FDA approved or CE marked?
Neuramis Volume Lidocaine Dermal Filler regulatory status: KFDA registered · CE marked · FDA DMF · ISO 13485 · EDQM certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.
How should Neuramis Volume Lidocaine Dermal Filler be stored at the clinic?
Store Neuramis Volume Lidocaine Dermal Filler between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.
Does Neuramis Volume Lidocaine Dermal Filler contain animal-derived ingredients?
No. Neuramis Volume Lidocaine Dermal Filler uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).
Can Neuramis Volume Lidocaine Dermal Filler be combined with other dermal fillers in the same session?
Yes — layered protocols combining different fillers are standard aesthetic practice. Neuramis Volume Lidocaine Dermal Filler can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.
Is Neuramis Volume Lidocaine FDA approved?
Neuramis is KFDA registered in South Korea and has passed FDA on-site inspection plus FDA Drug Master File registration. EDQM certification supports EU/UK distribution. While Medytox has filed regulatory documentation with FDA, Neuramis is not currently FDA-approved for direct US clinical use as of the most recent review. Practitioners should verify current regulatory status in their specific jurisdiction before importation and clinical use. The product holds CE marking for EU markets and ISO 13485 manufacturing certification.
Important Safety Information
Read Before Clinical Use
Neuramis Volume Lidocaine Dermal Filler is a prescription medical device for use only by licensed aesthetic practitioners. Common reactions include injection-site bruising, swelling, redness, and tenderness — generally resolving within days. Deep placement (subcutaneous and supraperiosteal layers) involves heightened anatomical awareness of facial vasculature; practitioners require access to hyaluronidase for emergency dissolution. Like all hyaluronic acid dermal fillers, treatment carries rare but serious vascular complication risks. Contraindicated in patients with known hypersensitivity to hyaluronic acid or lidocaine, active skin infection at the treatment site, pregnancy, or breastfeeding. Full contraindications, vascular complication protocols, aftercare, and emergency guidance are detailed on the dermal filler safety page.
Read Full Dermal Filler Safety Information →
Neuramis is a registered trademark of Medytox Inc.. Fillersfairy.com is a channel distributor and does not provide medical advice. This page is for informational purposes only and does not replace the manufacturer’s official Instructions for Use, which remains the authoritative source for clinical administration. Regulatory status varies by jurisdiction — buyers are responsible for verifying legal status before ordering. Last reviewed May 2026 against Medytox Inc. manufacturer documentation.
Margaret T. –
I’ve tried other fillers over the years for my cheekbones and under-eye troughs. That “12-month visible contouring” claim? Yep, I get a solid year of good correction before I feel the need for a tiny touch-up. Using this has actually saved me money in the long run because I don’t need injections as often. The lidocaine makes it comfortable enough – it’s not painless (it’s a needle, people!), but it’s manageable.THAT’s the look I want!
James K. Patel –
As someone focused on evidence-based practice, Neuramis Volume Lidocaine consistently delivers. The integrated 0.3% lidocaine is essential – patient feedback consistently highlights minimal discomfort compared to products needing separate numbing. The SHAPE™ technology isn’t just marketing speak; you feel it during injection. The gel flows smoothly through the 27G needle (aspirates cleanly, crucial step!), and the particle uniformity translates immediately into predictable, smooth placement and natural movement. No lumpiness, just clean integration. I primarily use it for mid-face volumization and temporal hollows. The documented 12-month longevity aligns with my clinical observations – patients maintain excellent contour well beyond the 6-month mark.
Sarah J. –
First time getting filler, specifically for my cheeks that were starting to look a bit flat. My practitioner recommended Neuramis Volume with Lidocaine and wow, did it live up to the hype. No panicking about pain mid-procedure! It’s been 4 months now and the results are exactly what I wanted: natural-looking volume that doesn’t make me look “done.”