PuriColl Rh Collagen 2.5ml*1
PURI COLL Rh is an injectable dermal matrix synthesized via recombinant DNA technology utilizing the verified human gene sequence GenBank X12842. Formulated with 15mg/ml of bioactive Type I and Type III collagen, it functions as a cellular scaffold to stimulate fibroblast proliferation and dermal remodeling without the immunogenic risks associated with bovine or porcine derivatives.
Verified Clinical Efficacy
Tissue Regeneration
+52.8%
Measurable improvement in dermal extracellular matrix density at 12 weeks. (Ref: Clinical Study 89-B)
Healing Acceleration
78% Faster
Wound closure and tissue repair rate compared to standard animal-derived collagen isolates.
Cell Viability
+19.33%
Increase in in-vitro fibroblast survival and migration rates over a 72-hour observation period.
Purity Standard
>99.9%
Structurally identical to native human collagen, completely free from pathogenic endotoxins.
Quantitative Formulation
Component
Concentration
Primary Mechanism of Action
Rh Collagen Type I
7.5 mg
Tensile strength and dermal structural support.
Rh Collagen Type III
7.5 mg
Granulation tissue formation and early-stage regeneration.
Hyaluronic Acid
50 mg
Extracellular matrix hydration and physical scaffold creation.
Succinic Acid
30 mg
Mitochondrial ATP synthesis and metabolic cellular activation.
PDRN
5 mg
DNA-level angiogenesis and cell cycle acceleration.
Peptide Complex
Proprietary
Galloyl Tripeptide-35 (MMP inhibition), Nicotinoyl Peptides (TGF-β pathway).
Standardized Treatment Protocol
Instrumentation
: 27G 1/2″ (13mm)
: 25G ~ 27G (38mm ~ 50mm)
Injection Plane: Mid-to-deep dermis via retrograde linear threading technique.
Dosing & Schedule
Primary Course: 2 distinct sessions.
Interval: 4 weeks (1 month) between sessions.
Maintenance: 1 to 2 subsequent sessions at 3 to 4-month intervals, evaluated by patient baseline.
Clinical FAQ
Q: Does this formulation require pre-treatment allergy testing?
A: No. Due to the 100% human-homologous genetic sequence (GenBank X12842) synthesized via bio-engineering, PuriColl Rh exhibits zero immunogenic animal proteins, negating the need for intradermal sensitivity testing.
Q: Can it be used concurrently with energy-based devices (EBDs)?
A: Yes. It acts as an effective adjuvant therapy. When sequenced correctly with RF or fractional lasers, the combination yields synergistic extracellular matrix stimulation.
Medical Disclaimer
For Professional Medical Use Only. Administration must be strictly performed by licensed healthcare practitioners trained in dermal injection techniques.
Contraindications: Do not administer to patients presenting with active cutaneous infections, autoimmune collagen-vascular disorders, or known hypersensitivity to succinic acid.
Manufactured by WEDERM Co., Ltd. (Seoul, Korea). Facilities maintain full and 13485 compliance for medical device synthesis. Outcomes are patient-dependent.
Linda Chen –
This is my first time trying recombinant human collagen. Honestly, it’s a huge upgrade from the old animal-sourced ones. Zero allergic reactions or redness for me. Used it with a derma pen, and a week later, my face feels so bouncy and hydrated. Worth the price.