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5-9

$46.08

10-19

$45.13

20-Illimité

$43.70

PuriColl Rh Collagen 2.5ml×1

Name: PuriColl Rh Collagen 2,5ml*1
Brand: fillersfairy
Price: 47.5 USD
Rating: 4.6 (245 reviews)

Recombinant Collagen Biostimulator · rhCollagen Type I+III + HA + PDRN

Quick Answer

PuriColl Rh Collagen by Aeterderm combines 15 mg of human-identical recombinant Type I and Type III collagen with 50 mg hyaluronic acid, 5 mg PDRN, and bioactive peptides in a single 2.5 mL syringe. The recombinant collagen — produced via gene expression matched to GenBank reference X12842 — provides immediate structural support and triggers fibroblast activity for sustained dermal renewal.

Last Reviewed

May 19, 2026

Manufacturer specification cross-verified

Treatment Protocol

3 sessions, 4 weeks apart. Maintenance every 6 months.

Why This Skinbooster Is Different

PuriColl Rh stands apart from animal-sourced (bovine or porcine) collagen by using a recombinant gene-expression platform that produces collagen 100% identical to human Type I and Type III. This eliminates immunogenicity, accelerates wound-repair response, and adds a synergistic PDRN/HA/peptide matrix that animal-collagen products lack. Two collagen types in one formulation provide both immediate structural scaffolding (Type I) and active fibroblast recruitment (Type III).

Mechanism of Action

Recombinant Human Collagen + HA + PDRN Synergistic Biostimulator. RHLC supplies a Type I collagen building block directly to the dermis. The recombinant origin avoids the immunogenicity of animal-derived collagens. Over 8–12 weeks, fibroblast activity is upregulated and new collagen synthesis matures, restoring dermal density gradually.

Specifications

Product Name	PuriColl Rh Collagen 2.5ml×1
Category	Recombinant Collagen Biostimulator
Active Ingredients	7.5 mg recombinant human-like collagen Type I + 7.5 mg recombinant human-like collagen Type III + 50 mg hyaluronic acid + 5 mg PDRN + 30 mg succinic acid + galloyl tripeptide-35 + nicotinoyl peptide
Mechanism Class	Recombinant Human Collagen + HA + PDRN Synergistic Biostimulator
Manufacturer	Aeterderm
Origin	Republic of Korea
Pack	1 × 2.5 mL pre-filled syringe
Lidocaine	Not included
Injection Technique	Mesotherapy nappage; or linear retrograde threading along rhytids
Injection Depth	Mid-dermis (2–3 mm)
Recommended Needle	30G or 31G recommended
Treatment Protocol	3 sessions, 4 weeks apart. Maintenance every 6 months.
Effect Duration	6–9 months after the initial 3-session course
Storage	2–25 °C, protect from light, do not freeze
Shelf Life	24 months unopened
Regulatory	CE-marked Class III medical device. RHC expression vector technology verified against GenBank reference X12842. Manufactured under KGMP.
SKU	FF-SB-PURICOLL-RH-COLLAGEN-2-5ML

Clinical Indications

Loss of dermal density and structural integrity
Sun-damaged and photoaged skin
Fine lines and early skin laxity
Post-procedure tissue recovery
Patients seeking animal-free collagen alternatives

Compare Within Skinbooster Category

Product	Active(s)	Mechanism	Protocol	Duration
PuriColl Rh Collagen 2.5ml×1	rhCollagen Type I+III + HA + PDRN	Recombinant Human Collagen + HA + PDRN Synergistic Biostimulator	3 sessions, 4 weeks apart. Maintenance every 6 months.	6–9 months after the initial 3-session course
Richesse Collafilo 2×30mg	30 mg/mL atelocollagen (porcine)	Porcine Atelocollagen Scaffold (terminal-peptide-cleaved)	Single session for most indications. Re-treatment at 4–6 months as needed.	Up to 12 months — atelocollagen scaffold persists with gradual native collagen replacement

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Frequently Asked Questions

What is PuriColl Rh Collagen 2.5ml×1?

PuriColl Rh Collagen is an Aeterderm Korean skinbooster combining 7.5 mg Type I + 7.5 mg Type III recombinant human-like collagen with 50 mg hyaluronic acid and 5 mg PDRN in a 2.5 mL pre-filled syringe. The collagen is synthesised via gene-recombinant technology — making it structurally identical to human collagen without animal origin.

Why use recombinant human-like collagen instead of animal-derived collagen?

Recombinant Human-Like Collagen (RHLC) is produced via a gene expression system matched to the human collagen gene (GenBank X12842). It is structurally identical to native human collagen, eliminating cross-species immunogenicity and removing the porcine or bovine cross-reactivity concerns that complicate atelocollagen products like Therafill or Richesse Collafilo.

How is PuriColl Rh different from Tesoro Collagen?

Both use recombinant human-like collagen as the principal active. PuriColl includes two collagen types (I + III at 7.5 mg each) plus 50 mg HA + 5 mg PDRN + succinic acid + peptides as a synergistic matrix. Tesoro Collagen uses a single recombinant collagen with sodium hyaluronate, trehalose, and amino acids — a simpler formulation. PuriColl is positioned as more complex and biostimulator-leaning; Tesoro as a clean RHLC-focused booster.

How is PuriColl Rh different from Richesse Collafilo?

Richesse Collafilo is a 3% atelocollagen product derived from porcine collagen — structurally similar to human but not identical, with the antigenic telopeptide removed to reduce immune response. PuriColl Rh uses recombinant gene-expressed human-identical collagen, removing the animal-origin step entirely. PuriColl also has the added HA + PDRN matrix; Richesse is primarily atelo collagen.

Do I need a skin allergy test before treatment?

Manufacturer guidance for recombinant human-like collagen is that pre-treatment allergy testing is not routinely required (in contrast to bovine-derived collagen products historically used in the US, which required 4-week test patches). However, patients with multiple allergies or prior reactions to injectables should still undergo a small test injection 2–4 weeks before full treatment.

How many sessions does PuriColl Rh require?

3 sessions spaced 4 weeks apart, then maintenance once every 6 months. Each 2.5 mL syringe is usually one session for a half-face or focal area; larger fields use 2 syringes per session.

What is the onset timeline for visible results?

Immediate effects from the HA component show within 1 week (hydration, plumpness). The collagen scaffold effect builds over 4 to 8 weeks. Full benefit — including improved dermal density and skin firmness — typically appears 8 to 12 weeks after the last session and persists 6 to 9 months.

Where can PuriColl Rh be injected?

Face, neck, décolletage, hands. Particularly suitable for thin or fragile skin where animal-collagen alternatives might trigger reactivity. Not injected into highly mobile areas like the perioral muscles in monotherapy.

Is PuriColl Rh CE marked?

Yes — CE-marked Class III medical device, manufactured under KGMP. The recombinant collagen gene expression process is validated against GenBank reference X12842 for sequence identity to human collagen.

How much does PuriColl Rh Collagen 2.5ml×1 cost?

PuriColl Rh Collagen 2.5ml×1 is priced at USD $47.50 per syringe on Fillersfairy, with wholesale pricing for licensed practitioners.

Source verification:→ EU MDR (CE marking framework)

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Regulatory Notice. CE-marked Class III medical device. RHC expression vector technology verified against GenBank reference X12842. Manufactured under KGMP. This product is manufactured outside the United States; FDA approval status is product-specific. For licensed healthcare professionals only. Practitioners are responsible for verifying regulatory status of this product in their jurisdiction before clinical use. Not for retail sale. Pricing subject to change.

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