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Rejuran Black Healer 2×2ml (Korean Domestic Version)
Polynucleotide (Classic Healer) · PN 2% (DOT™ Technology)
Quick Answer
Rejuran Black Healer is the classic anti-aging Healer formulation in the Korean domestic market packaging — the original Black Box. Each pack contains 2 × 2 mL syringes of 20 mg/mL PN (polynucleotide) extracted via DOT™ Technology from wild Korean salmon. This is the same PharmaResearch formulation sold globally as Rejuran Healer; the Korean domestic SKU is sourced through Korea's authorized wholesale channel.
About this Korean Domestic Version. This SKU is sourced through the Korean domestic pharmaceutical wholesale channel — the same PharmaResearch formulation, manufacturing facility, and DOT™ Technology as the international export version. Korean-domestic packaging includes a QR authentication code registered with the Korean MFDS verification system; this code is for the Korean market and may not return results when scanned via international authentication apps. This is normal for Korean-domestic-channel SKUs and is not an indicator of counterfeit product. The price advantage versus the export version reflects bypassing one or more international distribution tiers.
Last Reviewed
May 19, 2026
Manufacturer specification cross-verified
Treatment Protocol
3 sessions, 3–4 weeks apart. Maintenance every 4–6 months.
Why This Skinbooster Is Different
Rejuran Black Healer is the original anti-aging product in the Rejuran family — the formulation that defined the polynucleotide skinbooster category in Korea. The Korean domestic version provides the authentic PharmaResearch formulation at a lower price than the international export channel by bypassing the export distribution markup. Manufacturing, formulation, and clinical performance are identical to the export version.
Mechanism of Action
Classic Rejuran Healer (2% PN) — Korean Domestic Version. DOT™ Technology produces PN fragments in the 500–5000 base pair range, optimal for fibroblast adenosine A2A receptor engagement. Pure 2% PN without HA or lidocaine delivers the cleanest regenerative signal — the formulation that established the polynucleotide skinbooster category in Korea. The mechanism is anti-inflammatory cytokine modulation plus fibroblast proliferation and collagen synthesis across all dermal compartments.
Specifications
Clinical Indications
- Full-face skin regeneration and anti-aging
- Wrinkle reduction and dermal density improvement
- Skin elasticity restoration
- Pore size reduction
- Photoaged and sun-damaged skin
Compare Within Skinbooster Category
| Product | Active(s) | Mechanism | Protocol | Duration |
|---|---|---|---|---|
| Rejuran Black Healer 2×2ml (Korean Domestic Version) | PN 2% (DOT™ Technology) | Classic Rejuran Healer (2% PN) — Korean Domestic Version | 3 sessions, 3–4 weeks apart. Maintenance every 4–6 months. | 4–6 months after the initial 3-session course |
| Rejuran HB Hydro Booster | PN + HA + lidocaine | PN + HA Hybrid with Premixed Lidocaine (Hydro Booster) | 3 sessions, 3–4 weeks apart. Maintenance every 4–6 months. | 4–6 months sustained skin quality and hydration improvement |
| Vitaran PN 1ml×2 | PN 2% (20 mg/mL) | Polynucleotide Fibroblast Activator (full-face) | 3–4 sessions, 2–3 weeks apart. Maintenance every 4–6 months. | 4–6 months after the initial course |
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Frequently Asked Questions
Source verification:→ FDA 510(k) Database (verification)
Related Skin Boosters
Regulatory Notice. KFDA-approved Class III medical device. Manufactured by PharmaResearch in Korea for the domestic Korean market. International CE marking and DOT™ Technology patent apply to the underlying product. This product is manufactured outside the United States; FDA approval status is product-specific. For licensed healthcare professionals only. Practitioners are responsible for verifying regulatory status of this product in their jurisdiction before clinical use. Not for retail sale. Pricing subject to change.
Marcus Tan –
As a skincare enthusiast and reviewer, I’ve tried many skin boosters, but Rejuran Black remains a staple. Most guys hate feeling greasy, and the Black box is a king at balancing oil and water. After completing a 3-session protocol, my skin is significantly less oily and old acne scars have faded. The PN (Polynucleotide) tech offers much better regeneration than older formulas or basic mesotherapy. If you want a natural, textured skin upgrade, this is it.
Chloe Kim –
As an esthetician, I always tell my clients that Rejuran is an investment. You won’t see magic overnight. The key decision factor here isn’t instant volume, it’s cellular regeneration. A pro-tip: because this formula is dense, ask your injector to use a 33G Nano needle instead of the standard 30G. It reduces the pain significantly! Compared to previous generations of DNA treatments, the purity in this Korean version is unmatched. I saw my pore size reduce visibly after just two boxes. Highly recommend this seller, shipping was fast and the cold chain packaging was intact.
Emily Torres –
Tracking the shipment was super easy got text updates when it left Korea and cleared customs, knew exactly when it landed. Bonus points for the bulk discount, way better than what I found elsewhere. The Korean domestic version arrived, and honestly, it feels identical to what we used before. Clients are loving the results, especially for scarring and that deep hydration boost.