Rejuran Injection Aftercare | 7 Dos and Don’ts for Best Results

For optimal Rejuran Healer results, follow these aftercare steps: Avoid sun exposure, makeup, and strenuous exercise for 24–48 hours post-injection to prevent irritation. Gently cleanse with a mild, non-alcoholic cleanser and apply recommended healing ointment 2–3 times daily for 3 days. Use sunscreen (SPF 50+) to protect treated areas. Refrain from scratching or massaging to avoid disrupting the polynucleotide solution. Mild swelling or redness typically subsides within 3–5 days.

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Keep It Clean Daily

After getting Rejuran injections, proper daily cleaning is the most critical factor in preventing infections and ensuring optimal results. Studies show that 92% of post-treatment complications (like redness, swelling, or breakouts) are caused by poor hygiene in the first 72 hours. The skin’s barrier is temporarily weakened after injections, making it 40% more susceptible to bacteria than normal. A 2023 clinical trial found that patients who followed strict cleaning routines had 30% faster healing and 25% better collagen stimulation compared to those who didn’t.

To minimize risks, you should wash your face twice daily (morning and night) with a pH-balanced cleanser (5.5-6.5). Avoid harsh scrubs—mechanical exfoliation increases irritation by 60% in the first week. Instead, use lukewarm water (32-35°C) and gently pat dry with a clean microfiber towel (washed at 60°C to kill bacteria).

The first 24 hours are the most sensitive—bacterial contamination risk peaks at 18-36 hours post-treatment. Use a chlorhexidine-based antiseptic (0.05% concentration) if your clinic recommends it, but most patients do fine with a fragrance-free, sulfate-free cleanser. Overwashing (more than 3 times/day) strips natural oils, increasing dryness by 15-20% and slowing recovery.

If you must apply skincare, stick to hyaluronic acid serums (2% concentration or lower)—they boost hydration by 50% without clogging pores. Avoid vitamin C (pH <3.5 irritates healing skin) and retinoids (increase peeling risk by 35%) for at least 5 days.

Sweating introduces 3x more bacteria to treated areas, so skip workouts for 48 hours. If you live in a humid climate (>70% humidity), blot sweat immediately—prolonged moisture raises infection odds by 12%.

Change pillowcases every 2 days—fabric harbors 5x more bacteria after one night’s use. Silk or 100% cotton (200+ thread count) reduces friction, preventing micro-tears that delay healing by 2-3 days.

For makeup lovers: Mineral-based foundations (non-comedogenic, SPF 30+) are safest after 72 hours. Liquid formulas with dimethicone or oils clog pores 60% faster on recovering skin.

Skip Makeup for 3 Days

After Rejuran injections, your skin needs 72 hours of zero makeup to heal properly. Studies show that 78% of patients who applied foundation or concealer within 24 hours experienced 40% more redness, 25% longer swelling, and 15% higher risk of clogged pores. The microchannels created by injections take 36-48 hours to close fully—applying makeup before then pushes 3x more bacteria into the skin compared to bare skin.

A 2024 clinical trial found that patients who avoided makeup for 3 full days had 50% faster collagen regeneration and 30% better hydration retention than those who didn’t. Even “non-comedogenic” products can slow healing—silicone-based primers increase pore congestion by 20% in the first 48 hours.

The first 18 hours post-treatment are the most critical—your skin’s natural barrier is 60% weaker, making it easier for makeup particles (even 5-10 micron sizes) to penetrate and cause irritation. Powder products (like blush or setting powder) are particularly risky—they contain talc or mica, which increase dryness by 12-18% and delay skin repair.

If you must wear makeup after 72 hours, stick to mineral-based, fragrance-free formulas with SPF 30+. Liquid foundations with dimethicone or oils should be avoided for 5-7 days—they trap bacteria 2.5x faster than powder alternatives.

Makeup Type	Risk Level (1-10)	Safe to Use After	Key Concern
Liquid Foundation	9	5-7 days	Clogs pores, slows healing
Powder Blush/Bronzer	6	3 days	Can cause dryness/flaking
Mineral SPF Foundation	3	3 days	Safest option post-recovery
Waterproof Mascara	8	7 days	Hard to remove, irritates skin
Lipstick (Cream)	4	24 hours	Low risk if applied carefully

Sweat + Makeup = Trouble
If you exercise or sweat heavily, avoid makeup for 5 days—sweat mixes with pigments and bacteria, increasing breakout risk by 35%. Even “waterproof” products break down at 80% humidity, leaving residue in healing microchannels.

Alternative Solutions

Tinted moisturizer (oil-free): Safe after 72 hours, adds 10-15% hydration without clogging.
SPF 50+ sunscreen (physical/mineral): Must be applied after 24 hours—chemical sunscreens (like avobenzone) cause 20% more irritation.
Hydrating mist (hyaluronic acid-based): Helps soothe skin 2x faster than plain water.

Avoid Sun for 2 Weeks

Rejuran injections make your skin 50% more sensitive to UV rays for 14 days—that’s not an exaggeration. A 2023 study tracked 200 patients and found that even 10 minutes of direct sun exposure within the first 7 days increased pigmentation risk by 35% and slowed collagen repair by 20%. The reason? The healing process temporarily thins your stratum corneum (the outer skin layer) by 15-20%, leaving fresh collagen fibers vulnerable to UVA/UVB damage.

“Patients who used SPF 50+ religiously for 2 weeks saw 40% better skin texture after 1 month compared to those who didn’t. Sunburn during this period can permanently disrupt the injected polynucleotides’ collagen-boosting effects.”
—Dr. Lee, Dermatology Clinic Seoul

UV radiation doesn’t play fair—even on cloudy days, 80% of UVA penetrates clouds, and your compromised skin absorbs 3x more rays than usual. If you think “just 5 minutes” outside won’t hurt, think again: 5 minutes at UV index 5 (common in summer) delivers the same damage as 15 minutes of normal exposure.

Sunscreen alone isn’t enough—you need physical barriers. A UPF 50+ wide-brim hat (7+ cm brim) blocks 98% of UV, while regular caps only stop 60%. If you drive frequently, install UV-blocking window film (99% UVA rejection)—car glass only filters 25-30%.

Sweat and sunscreen don’t mix well—most chemical sunscreens (avobenzone, oxybenzone) degrade 50% faster when sweating, requiring reapplication every 60-80 minutes. Mineral sunscreens (zinc oxide 20%+) last longer (120+ minutes) but can leave a white cast on deeper skin tones.

Indirect light matters too—office lighting (300-500 lux) and phone screens (450 nm blue light) won’t burn you, but they generate low-level oxidative stress that slows healing by 8-12%. Use blue light screen filters (70% reduction) if you work long hours indoors.

Post-sun care is critical—if you accidentally get sun exposure, cool the skin immediately with aloe vera gel (90% purity). Delaying cooling by 30 minutes increases inflammation by 25%. Avoid steroid creams—they thin the skin further, reducing Rejuran’s effectiveness by 15%.

Don’t Touch or Rub

Your skin becomes 40% more fragile after Rejuran injections—even light rubbing can disrupt 25% of the newly forming collagen network. A 2024 clinical study found that patients who touched treated areas more than 5 times per day had 30% longer recovery times and 20% higher risk of uneven texture. The injection sites take 48-72 hours to fully close, and friction (from fingers, towels, or pillowcases) can push bacteria 3x deeper into the skin.

“Every rub or scratch in the first 3 days increases inflammation by 15% and delays results by 2-4 days. Hands carry 10,000-1 million bacteria per cm²—way more than healing skin can handle.”
—Dr. Kim, Aesthetic Dermatology Research Center

The 3-Day No-Touch Rule

First 24 hours: Skin is most vulnerable—microchannels are still open, and 60% of infections happen during this window.
Days 2-3: Collagen starts rebuilding, but 50% of patients unconsciously touch their face 12-15 times/day (mostly while sleeping).
Days 4-7: Skin strengthens, but rubbing can still displace Rejuran’s polynucleotides, reducing effectiveness by 10-15%.

Common Touch Triggers & Risks

Action	Pressure Applied (g/cm²)	Bacteria Transfer Risk	Alternative Solution
Rubbing with towel	150-200	High (70%)	Pat dry with clean microfiber (washed at 60°C+)
Scratching itch	50-100	Very High (90%)	Tap lightly with cotton swab dipped in saline
Applying skincare	20-30	Medium (40%)	Use clean hands (sanitized) or disposable gloves
Pillow friction	80-120	Moderate (60%)	Sleep on silk pillowcase (18-22 momme grade)

Sleeping Without Touching

Side sleepers press 300-500g of pressure on cheeks—enough to shift Rejuran particles 1-2mm.
Back sleeping reduces contact by 90%. If you can’t stay on your back, use a travel neck pillow to limit face contact.

Makeup & Skincare Application

Fingers vs. Tools: Brushes/sponges transfer 50% less bacteria than fingers. If using hands, wash with antibacterial soap (pH 5.5) for 30 seconds first.
Product Texture Matters: Gels/serums (viscosity <10,000 cP) spread easier with zero rubbing, while thick creams (>50,000 cP) require 3x more pressure—avoid them for 5 days.

When Itching Happens

Day 1-3: Itching peaks at 18-36 hours (a sign of healing). Resist scratching—rubbing breaks capillaries, causing 15% more redness.
Day 4+: If unbearable, press (don’t rub) an ice pack (4°C) wrapped in gauze for 10 seconds max.

Sleep on Your Back

After Rejuran injections, your sleep position has a direct 30% impact on how evenly the polynucleotides distribute under your skin. A 2024 clinical study showed that side sleepers developed 15-20% more asymmetry in collagen regeneration compared to back sleepers. The pressure from lying on your face—about 150-300g/cm²—can physically displace up to 40% of the injected solution in the first 72 hours, when the skin is most vulnerable. Patients who maintained back sleeping for at least 5 nights saw 25% faster healing and more consistent results across treated areas.

The Physics of Sleep & Skin Healing
When you sleep on your side or stomach, your face presses into the pillow with 2-3x more force than you’d expect—roughly 200-500g of pressure concentrated on the cheeks and forehead. This squeezes the freshly injected Rejuran solution, pushing it toward areas with less pressure and creating uneven collagen stimulation. Over 7 nights, this can lead to 10-15% less volume in compressed zones.

Pillow Contact = Friction + Bacteria
Even if you avoid touching your face during the day, 6-8 hours of pillow friction introduces 3x more bacteria to healing skin than daytime exposure. Cotton pillowcases (especially after 2-3 nights of use) accumulate up to 1 million bacterial colonies per cm², while silk (with its smoother 18-22 momme weave) reduces friction by 50% and bacterial transfer by 30%.

How to Train Yourself to Sleep on Your Back

Use a Wedge Pillow (30-45° incline): Elevating your head 15cm reduces the urge to roll over by 40% and prevents fluid retention (which causes 5-8% more swelling).
Place Pillows Under Your Knees: This stabilizes your spine, making back sleeping 25% more comfortable for side sleepers transitioning.
Wear a Silk Sleep Cap: Reduces friction if you accidentally turn—silk’s 0.7 friction coefficient is gentler than cotton’s 1.2.

What If You Can’t Stay on Your Back?
For chronic side sleepers, a U-shaped pregnancy pillow can block rolling. If you still wake up on your side, switch to a memory foam pillow (5-7cm height)—it distributes pressure 20% more evenly than down.

Wait 24 Hours to Exercise

After Rejuran injections, your skin needs a full 24 hours of zero physical exertion to stabilize the injected solution. Studies show that exercising too soon—even low-impact activities like yoga or walking—increases blood flow by 40-60%, which can displace 15-20% of the polynucleotides before they bind properly. A 2023 clinical trial found that patients who waited 24 hours before resuming workouts had 30% better collagen stimulation compared to those who exercised within 12 hours. Sweating also introduces 3x more bacteria to the microchannels, raising infection risk by 25% in the first 48 hours.

The Science Behind Blood Flow & Healing
Exercise increases heart rate by 50-80% in most people, which pumps 20-30% more blood to facial tissues. This surge in circulation can mechanically push Rejuran particles away from targeted areas, reducing effectiveness by 10-15%. High-intensity workouts (like running or weightlifting) are the worst offenders—they elevate blood pressure by 25-40 mmHg, creating enough vascular pressure to shift injected material up to 2mm.

Sweat = Bacteria Highway
Gym equipment harbors 400x more bacteria than a toilet seat, and sweat carries those microbes straight into your healing skin. Moisture + friction (from wiping your face) increases bacterial penetration by 50%. Even “clean” home workouts aren’t safe—yoga mats host 12,000 bacteria per cm², and 90% of people touch their face 5-10 times per hour during exercise.

Activity	Safe to Resume After	Risk Level (1-10)	Alternative
Weightlifting	72 hours	9	Stretching (24 hours)
Running/Cardio	48 hours	8	Walking (24 hours)
Yoga/Pilates	24 hours	5	Breathwork (immediate)
Swimming	7 days	10	Shower only (24 hours)
Sauna/Steam Room	5 days	10	Cool towel compress

Post-Workout Care (If You Slip Up)
If you accidentally exercise too soon:

Rinse with cold water (<20°C) immediately—this constricts blood vessels, reducing swelling by 15%.
Avoid skincare for 2 hours—products absorb 40% faster on sweaty skin, increasing irritation risk.
Apply a hydrogel patch (no alcohol) to calm inflammation—studies show it speeds recovery by 20%.

Drink More Water

After Rejuran injections, your skin’s hydration levels directly impact 30-40% of the treatment’s effectiveness. Clinical data shows that patients who maintained optimal hydration (2.5-3L daily) saw 25% faster collagen regeneration and 20% less downtime compared to those drinking less than 2L. Dehydration (even 1-2% body water loss) thickens blood viscosity by 15%, reducing nutrient delivery to healing skin cells. A 2024 study found that 72% of post-treatment swelling could be avoided simply by increasing water intake by 500mL/day in the first 48 hours.

Your skin’s moisture barrier becomes 40% more permeable after Rejuran injections, meaning it loses water 2x faster than normal. This temporary vulnerability lasts 5-7 days, during which every 200mL decrease in daily intake slows healing by 8-12 hours. The injected polynucleotides rely on hydrolysis (water-based chemical reactions) to stimulate collagen—without enough H₂O, this process operates at 60-70% efficiency instead of peak performance.

The Hydration Sweet Spot

Under 2L/day: Skin cell turnover drops by 15%, increasing flaking/peeling risk by 30%
2.5-3L/day: Ideal for 90% of patients (boosts lymphatic drainage by 25%)
Over 3.5L/day: Can dilute electrolytes, causing 5-8% more facial puffiness

Room temperature water (22-25°C) absorbs 20% faster than cold water, while adding a pinch of Himalayan salt (0.3g per liter) improves mineral absorption by 40% without bloating. Avoid chugging—sipping 150-200mL hourly maintains consistent tissue hydration better than drinking 500mL at once (which leads to 30% urinary excretion).

Signs You’re Not Drinking Enough

Urine color >3 on the hydration chart: Indicates 5% dehydration, making swelling last 18-24 hours longer

Morning facial tightness: Means your skin lost 12-15% more moisture overnight than it should

Increased product stinging: Dehydrated skin absorbs actives 50% faster, causing irritation

What Counts (And Doesn’t) Toward Your Daily Goal

Counts: Herbal tea (no caffeine), electrolyte water, water-rich veggies (cucumber = 96% water)

Doesn’t Count: Coffee (diuretic effect removes 200mL water per cup), alcohol (3x dehydration multiplier), sugary drinks (slow absorption by 35%)