There are three main types of PLLA (poly-L-lactic acid): PLDA, PDLA and PLLA. PLDA has a lasting effect of 12 to 18 months and is suitable for facial contouring and fine line filling, with side effects less than 0.5%; PDLA degrades quickly and the effect lasts for 12 to 18 months; PLLA has an effect within 3 to 6 months after injection and is suitable for women over 40 years old. An injection once a year can maintain the effect.
PLDA (Poly-D-Lactic Acid)
PLDA (Poly-D-Lactic Acid) has become a hot trend in female medical beauty. As a biodegradable polymer, PLDA has become an ideal material for facial contouring, anti-aging, and skin reconstruction treatments.
As a non-permanent filler material, PLDA is particularly suitable for wrinkle filling, facial contouring, and shaping of the chin, nose bridge, and other parts. Compared with other common fillers, such as hyaluronic acid and botulinum toxin, PLDA can usually provide lasting effects for 12 to 18 months after injection, because PLDA can stimulate the production of natural collagen in the skin layer to form a long-lasting support structure.
The effect of PLDA is not a simple “filling” treatment, but by stimulating the skin to repair itself. For example, when shaping the facial contour, PLDA will gradually promote the production of collagen in the skin after injection, reducing the appearance of fine lines and wrinkles. According to clinical data, about 70% of female patients clearly feel that the skin’s elasticity has increased and the facial lines are more three-dimensional within 6 months after PLDA treatment.
The effect of using PLDA injection to improve the chin contour can usually last for more than 1 to 1.5 years, avoiding the common problem of “sagging” or “fading” after filler injection.
PLDA is also used to fill fine lines around the eyes. After injection, the wrinkle effect usually lasts for 12 to 18 months, and it is often more natural and less likely to appear “false”.
The amount of PLDA injected may vary, generally young patients only need slight filling and contouring adjustments, while older patients need more treatment to restore the skin’s firmness and elasticity.
The global PLDA market has grown by about 25% in the past 5 years, After injection, PLDA does not cause allergic reactions, and is not likely to cause lumps or unnatural filling effects. After PLDA injection treatment, the incidence of side effects is less than 0.5%, and most adverse reactions (such as redness, swelling, and bruising) usually subside on their own within a few days. In general, the degradation period after PLDA injection is 6 months to 1 year, and after complete degradation, the skin will return to its pre-treatment state
PDLA (Poly-D,L-Lactic Acid)
PDLA (Poly-D,L-Lactic Acid), as a polymer with both D-lactic acid and L-lactic acid monomers, has gradually become an important material for filling, anti-aging treatment and facial contouring.
The molecular structure of PDLA makes its degradation rate faster than PLLA, and it usually takes 6 months to 1 year to completely degrade in the body. In anti-aging treatment, PDLA injection can stimulate the skin to produce new collagen, clinical data show that about 80% of patients will see skin tightening effects within 6 months.
PDLA is also widely used in facial contouring, especially in injection filling of the chin, cheekbones, bridge of the nose and other parts. After PDLA injection, the improvement effect of facial contour can last for 12 to 18 months, and there is no obvious sagging or regression after injection.
In the treatment of facial fine lines and fine lines around the eyes, PDLA injection can effectively reduce the depth of fine lines and restore the skin to its smoothness. Many women say that after PDLA injection, the skin looks more natural and does not feel like filler.
The incidence of side effects of PDLA is very low, usually less than 1%.
In terms of price, the cost of each injection is between $800 and $1,500. The demand for PDLA has increased by about 20% in the past few years, especially in the Asian market and the high-end medical beauty market in Europe and the United States.
PLLA (Poly-L-Lactic Acid)
PLLA (Poly-L-Lactic Acid) is a biodegradable synthetic polymer, often referred to as a “deep stimulation filler”. After PLLA injection, it usually takes 3 to 6 months to see obvious results, and the effect will last for the next 12 months or even longer, which is sought after by women.
As we age, the face begins to sag, wrinkle and dent. After PLLA injection, about 80% of patients can see the effect of skin tightening and wrinkle reduction within 6 months. Many women say that PLLA injection can effectively enhance facial contours, make the jaw line more prominent, and make the cheekbones more three-dimensional. PLLA injections do not need to be done frequently, only once a year or every two years, and the long-term effect can be maintained, which is very attractive.
After PLLA treatment, about 70% of women found that the skin texture improved, the radiance and firmness gradually recovered after 3 months, especially the anti-aging option for women over 40 years old.
PLLA usually requires 2 to 3 injections, with an interval of 4 to 6 weeks between each injection. The treatment effect of each injection usually gradually appears within 2 to 3 months after the injection. The treatment cost of PLLA is usually higher than that of hyaluronic acid and botulinum toxin. The cost of each injection is about $1,000 to $2,000, and the high anti-aging effect makes many women willing to pay the fee.