AEGEN Bio Co., Ltd. · Republic of Korea
Vellux 100U is a Korean botulinum toxin type A manufactured by AEGEN Bio Co., Ltd. in South Korea. Each single-use vial contains 100 units of botulinum toxin type A as freeze-dried (lyophilized) white powder for reconstitution with 0.9% sterile saline.
Why this product is different
Vellux is manufactured by AEGEN Bio Co., Ltd., a Korean pharmaceutical company that operates its own botulinum toxin production line and maintains a proprietary working strain of Clostridium botulinum. Vellux is freeze-dried (lyophilized), supplied as white powder in a colorless transparent vial.
Mechanism of action
Botulinum toxin type A is a presynaptic neuromuscular blocker. Following injection into target muscle, the toxin’s heavy chain binds to specific receptors on motor nerve terminals; the light chain is internalised into the nerve cytoplasm, where it enzymatically cleaves SNAP-25 — a SNARE complex protein required for acetylcholine vesicle fusion at the neuromuscular junction. Without SNAP-25, acetylcholine release into the synaptic cleft is blocked, the motor nerve cannot signal the muscle fibre to contract, and the targeted muscle relaxes. New axon terminals eventually sprout and restore neuromuscular signalling, at which point clinical effect wanes.
Specifications
Common application zones
Application zones below are common indications for which botulinum toxin type A is used by practitioners. Specific dosing per zone is determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Contraindications
Frequently asked questions
Vellux 100U is a Korean botulinum toxin type A manufactured by AEGEN Bio Co., Ltd. in South Korea. Each single-use vial contains 100 units of botulinum toxin type A as freeze-dried (lyophilized) white powder for reconstitution with 0.9% sterile saline before injection.
Vellux is manufactured by AEGEN Bio Co., Ltd., a Korean pharmaceutical company that operates its own botulinum toxin production line and uses a proprietary working strain of Clostridium botulinum.
Vellux is freeze-dried (lyophilized), supplied as white powder in a colorless transparent vial. After reconstitution with 0.9% sterile saline, the solution is clear and colourless.
Common aesthetic application zones include glabellar lines, forehead lines, lateral canthal lines, masseter contouring, brow lift refinement, mentalis muscle, and platysma bands. Specific dosing per zone is determined by the treating practitioner.
Both are Korean freeze-dried botulinum toxin type A products from different manufacturers using different working strains. Vellux is manufactured by AEGEN Bio. Botulax is manufactured by Hugel Pharma in Chuncheon, South Korea.
Both are Korean freeze-dried botulinum toxin type A products from different manufacturers. Vellux is manufactured by AEGEN Bio. Meditoxin is manufactured by Medytox using the Hall A-hyper working strain (KAIST lineage).
Both are Korean freeze-dried botulinum toxin type A products from different manufacturers. Vellux is manufactured by AEGEN Bio. Hitox is manufactured by Humedix Co., Ltd. in Seongnam, South Korea.
Both are Korean freeze-dried botulinum toxin type A products from different manufacturers. Vellux is manufactured by AEGEN Bio. Coretox is manufactured by Medytox and is differentiated as a pure-neurotoxin (150 kDa core) product with complexing accessory proteins removed.
Onset and duration vary with individual anatomy, muscle mass, metabolism, treatment zone, and dosing strategy. Practitioners can refer to AEGEN Bio’s product documentation for general expectations.
Store unopened vials at 2–8 °C, protected from light. Do not freeze. After reconstitution with 0.9% sterile saline, use within 24 hours when stored refrigerated. Discard any unused reconstituted product per institutional protocol.
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