Quick Answer
Richesse Collafilo is a Korean atelocollagen tissue supplement from JDBIO containing 3% porcine-derived atelocollagen (30 mg/mL) — the terminal antigenic peptides are cleaved to minimize immunogenicity, leaving collagen that is 99% structurally similar to human skin collagen. The 2 × 1 mL pack provides a collagen scaffold that persists in tissue for up to 12 months while being gradually replaced by native collagen.
Why This Skinbooster Is Different
Richesse Collafilo uses porcine atelocollagen — distinct from the recombinant human-like collagen in PuriColl Rh or Tesoro Collagen. Porcine collagen is structurally closer to human collagen than bovine; the atelocollagen processing removes the antigenic telopeptides. The 12-month tissue persistence is significantly longer than typical skinbooster duration because the implanted collagen acts as a physical scaffold replaced by host tissue over time.
Mechanism of Action
Porcine Atelocollagen Scaffold (terminal-peptide-cleaved). Porcine atelocollagen with antigenic telopeptides removed is implanted into the mid-dermis. The collagen scaffold provides immediate structural support (analogous to a soft filler) while serving as a template for host fibroblasts to deposit native collagen over the following months. As the implanted scaffold gradually degrades, host tissue replaces it — producing durable density restoration rather than transient hydration.
Frequently Asked Questions
What is Richesse Collafilo 2×30mg?
Richesse Collafilo is a Korean collagen tissue supplement from JDBIO supplied as 2 × 1 mL syringes containing 30 mg/mL (3%) atelocollagen each. The atelocollagen is derived from purified porcine collagen with the terminal antigenic peptides removed, producing a collagen 99% structurally similar to human dermal collagen.
What is atelocollagen and how does it differ from regular collagen?
Atelocollagen is collagen with the terminal telopeptides cleaved off. Telopeptides are the short non-helical regions at each end of the collagen molecule that contain the species-specific antigenic sequences. Removing them produces collagen that is largely free of cross-species immune recognition while retaining the central triple-helical structure that gives collagen its function.
Where is the collagen sourced from?
Porcine — from pig collagen. Porcine collagen is preferred over bovine because pig skin collagen has a closer molecular structure to human collagen than cow collagen does. The atelocollagen processing further reduces species-specific antigenicity. Patients with religious or ethical concerns about porcine ingredients should consider PuriColl Rh (recombinant human-like) or Tesoro Collagen (RHLC) instead.
How does Richesse Collafilo differ from PuriColl Rh?
PuriColl Rh uses recombinant human-like collagen produced via gene expression — zero animal origin, structurally identical to human Type I and III collagen. Richesse Collafilo uses porcine atelocollagen — animal-sourced but processed to minimize immunogenicity. Mechanism differs too: PuriColl is a skinbooster with HA + PDRN matrix; Richesse is closer to a collagen scaffold filler with longer tissue persistence.
Is a skin allergy test required before treatment?
Historically, bovine collagen products in the US required mandatory pre-treatment skin testing. Modern atelocollagen products like Richesse Collafilo have substantially reduced immunogenicity, but manufacturer guidance still recommends a test injection 2–4 weeks before full treatment for patients with multiple allergies or known protein sensitivities.
How long do results last?
Manufacturer data shows atelocollagen scaffold persistence of approximately 70% of initial mass at 12 months post-implantation — significantly longer than typical skinboosters. As the implanted atelocollagen is gradually replaced by host-synthesised native collagen, the result transitions from implanted to endogenous.
Is Richesse Collafilo a filler or a skinbooster?
Richesse Collafilo occupies a hybrid position — it is closer to a soft collagen filler than a classical skinbooster. It provides immediate volume support similar to a filler, plus the longer-term biostimulator effect of triggering host collagen synthesis as it integrates. Marketing literature variably describes it as a 'tissue supplement' or 'collagen filler' depending on the indication.
Where can Richesse Collafilo be injected?
Nasolabial folds, glabellar lines, forehead, periocular area (with caution), and shallow depressed scars. Not used for lip augmentation (different rheology required) or for deep volume restoration (deeper, denser fillers are appropriate for that).
Is Richesse Collafilo certified?
Yes — CE-marked Class III medical device, KFDA-licensed in Korea, manufactured under KGMP and ISO 13485. The porcine collagen source is from food-grade purified material with documented telopeptide removal.
How much does Richesse Collafilo 2×30mg cost?
Richesse Collafilo 2×30mg is priced at USD $48.50 per 2-syringe box on Fillersfairy, with wholesale pricing for licensed practitioners.
Rachel Gomez –
I have super sensitive skin and used to get swollen from traditional fillers. Because this is atelocollagen (they removed the allergy-triggering proteins), I had zero reaction. Just some minor bruising from the needle. It settles into the tissue so beautifully. If you’ve had bad luck with HA fillers making you look puffy, switch to this. I’ve linked my skincare journey on my blog if anyone wants to see the healing process!
Zinnia Bloom –
This was my first time trying a Korean skin booster at home. I was super nervous but the syringe is very smooth to push so it was easier than expected. The immediate hydration boost is crazy. My only regret is not trying it sooner!
Elena Petrova –
The 3% concentration is just right, it glides so smoothly during injection. I used it for a full-face microneedling treatment on myself. By the third day, my skin looked amazing—pores were tighter and I just looked refreshed. Compared to other collagens on the market, this feels purer and has a shorter downtime. Great value for money.