Exo One Exosome (2 vials/box)

Why This Skinbooster Is Different

Mechanism of Action

Specifications

Product Name	Exo One Exosome (2 vials/box)
Category	Exosome Biologic
Active Ingredients	Vial 1: lyophilized human-derived exosome powder (≥6 billion particles); Vial 2: hyaluronic acid activating solution
Mechanism Class	Stem-cell-derived Lyophilized Exosome Booster
Manufacturer	JDBIO Co., Ltd.
Origin	Republic of Korea
Pack	2 vials per box (1 × lyophilized exosome powder + 1 × HA activating solution)
Lidocaine	Not included
Injection Technique	Topical application post-laser/microneedling; or microneedle-assisted dermal delivery (nano-infusion pen)
Injection Depth	Topical to superficial dermis via microneedle channels (0.5–1.5 mm)
Recommended Needle	30G–34G for injection; nano-infusion or microneedling for topical delivery
Treatment Protocol	1 vial per session. 3–4 sessions, 2–4 weeks apart. Maintenance every 2–3 months.
Effect Duration	3–4 months of cumulative skin quality improvement
Storage	2–8 °C refrigerated; activated solution use within 24 hours
Shelf Life	24 months unopened (lyophilized)
Regulatory	Korean MFDS-registered as cosmeceutical for topical and microneedle-assisted delivery. Not approved for intradermal injection in most jurisdictions. Manufactured under KGMP.
SKU	FF-SB-EXOONE-EXOSOME-2VIAL

Clinical Indications

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Frequently Asked Questions

What is Exo One Exosome and how is it supplied?

Exo One is a Korean exosome skin treatment from JDBIO supplied as 2 vials per box — one lyophilized exosome powder (≥6 billion particles) and one hyaluronic acid activating solution. The two are mixed immediately before use to form an active exosome serum for topical or microneedle-assisted delivery.

How is Exo One different from Hanheal Exosome?

Hanheal Exosome (BNC Global Korea) is fibroblast-derived exosomes designed for dermal mesotherapy with strong fibroblast signalling cargo. Exo One (JDBIO) is human-derived exosomes designed primarily for post-procedure recovery and topical/microneedle delivery. Different cell sources, different positioning.

How is Exo One different from 2XSOME?

Both are dual-vial exosome systems requiring reconstitution. 2XSOME (Maypharm) is stem-cell-derived with an activating diluent rich in hydrolyzed collagen + sodium DNA + copper tripeptide + vitamins. Exo One uses a simpler HA-only activator. 2XSOME emphasises the synergistic cocktail; Exo One emphasises clean exosome delivery.

How is Exo One reconstituted?

Remove both vials from refrigeration and let them reach room temperature. Transfer the full HA solution into the lyophilized exosome powder vial. Gently swirl — do not shake — until fully dissolved. Use the reconstituted solution within 24 hours, or immediately for best potency.

What is the recommended delivery technique?

Topical post-laser or post-microneedling, or via nano-infusion pen / microneedling device at 0.5–1.5 mm depth. The product is positioned for cosmeceutical use rather than direct intradermal injection. Always verify regulatory status in your jurisdiction for exosome products.

How many sessions are typical?

1 vial per session, 3–4 sessions spaced 2–4 weeks apart. Maintenance every 2–3 months. Heavily compromised skin (post-aggressive laser, acne flares, atopic background) may benefit from weekly sessions during recovery phase.

Are exosome products approved for injection?

Most Korean exosome products including Exo One are registered as topical cosmeceuticals — not as injectable medical devices. Intradermal injection of exosomes is not approved by the FDA, EMA, or most national regulators as of 2026 due to insufficient clinical safety data. A 2024 case report documented dermal necrosis after exosome injection. Practitioners must verify local approval before any non-topical use.

Why mix powder + liquid instead of pre-mixed solution?

Exosomes are extracellular vesicles whose membrane stability degrades rapidly in aqueous solution. Lyophilization (freeze-drying) preserves vesicle integrity for up to 24 months. Reconstitution at point of use maintains exosome viability for the procedure window.

Where is Exo One manufactured?

Manufactured by JDBIO Co., Ltd. in the Republic of Korea, under KGMP quality standards. Registered with Korean MFDS as a cosmeceutical.

How much does Exo One Exosome cost?

Exo One Exosome (2 vials per box) is priced at USD $63.00 on Fillersfairy, with wholesale pricing for licensed practitioners.

Source verification:→ Korean MFDS (regulatory authority)

Related Skin Boosters

Regulatory Notice. Korean MFDS-registered as cosmeceutical for topical and microneedle-assisted delivery. Not approved for intradermal injection in most jurisdictions. Manufactured under KGMP. This product is manufactured outside the United States; FDA approval status is product-specific. For licensed healthcare professionals only. Practitioners are responsible for verifying regulatory status of this product in their jurisdiction before clinical use. Not for retail sale. Pricing subject to change.