2XSOME Dual-Exosome

Why This Skinbooster Is Different

Mechanism of Action

Specifications

Product Name	2XSOME Dual-Exosome
Category	Exosome Biologic
Active Ingredients	1SOME (100 mg powder): stem-cell-derived lyophilized exosome rejuvenating powder + sodium hyaluronate. 2SOME (6 mL diluent): hydrolyzed collagen + sodium DNA + Copper Tripeptide-1 + vitamins.
Mechanism Class	Stem-Cell Exosome + Collagen-Peptide Activator (dual-vial reconstitution)
Manufacturer	Maypharm Co., Ltd. (Facepharm Korea)
Origin	Republic of Korea
Pack	1 × 100 mg lyophilized exosome powder + 1 × 6 mL activating diluent
Lidocaine	Not included
Injection Technique	Topical post-microneedling or mesotherapy delivery — mix 1SOME and 2SOME immediately before use
Injection Depth	Topical via microchannels (0.5–1.5 mm) or superficial dermis (1–2 mm) for mesotherapy
Recommended Needle	30G or 31G for mesotherapy; nano-infusion / microneedling for topical-via-channel delivery
Treatment Protocol	1 set per session. 3–4 sessions, 2–4 weeks apart. Maintenance every 2–3 months.
Effect Duration	3–4 months cumulative skin quality improvement
Storage	2–8 °C refrigerated for lyophilized powder; room temperature for diluent. Use mixed solution within 24 hours.
Shelf Life	24 months unopened (lyophilized powder); 24 months for diluent
Regulatory	Korean MFDS-registered. CPNP (EU Cosmetic Products Notification Portal) and SCPN (Korean Skin Cosmetic Products Notification) certified. Manufactured under KGMP. Not approved for intradermal injection in most jurisdictions.
SKU	FF-SB-2XSOME-DUAL-EXOSOME

Clinical Indications

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Frequently Asked Questions

What is 2XSOME Dual-Exosome?

2XSOME is a Korean dual-vial exosome skinbooster by Maypharm (Facepharm). Vial 1 (1SOME) is 100 mg lyophilized stem-cell-derived exosome powder with sodium hyaluronate. Vial 2 (2SOME) is 6 mL activating diluent containing hydrolyzed collagen, sodium DNA, Copper Tripeptide-1, and vitamins. The two are mixed immediately before use.

How is 2XSOME different from Exo One?

Both are dual-vial exosome systems. Exo One pairs lyophilized exosomes with a simpler HA-only activator. 2XSOME pairs exosomes with a more complex diluent containing hydrolyzed collagen + sodium DNA + Cu-tripeptide + vitamins. 2XSOME's activator is itself a multi-active cocktail; Exo One's is cleaner. Positioning differs accordingly: 2XSOME for multi-target indications, Exo One for focused exosome delivery.

How is 2XSOME different from Hanheal Exosome?

Hanheal is fibroblast-derived exosomes designed primarily for direct dermal mesotherapy. 2XSOME is stem-cell-derived exosomes paired with a multi-active activator and positioned for topical/microneedle delivery. Different cell sources, different delivery, different positioning.

What does Copper Tripeptide-1 (GHK-Cu) in the diluent do?

GHK-Cu is one of the most well-studied signalling peptides in skin science. It stimulates fibroblast collagen synthesis, modulates MMP-2 and MMP-9 expression (controlling matrix turnover), and supports angiogenesis. Including GHK-Cu in the activating diluent adds an independent signalling layer on top of the exosome cargo.

What is the role of sodium DNA in the diluent?

Sodium DNA is a PDRN-equivalent ingredient — short DNA polymer fragments that bind the adenosine A2A receptor on fibroblasts and trigger anti-inflammatory and regenerative responses. Adding sodium DNA to the 2SOME diluent layers a PDRN-style signal on top of the stem-cell exosomes — making 2XSOME a hybrid exosome-PDRN product.

How is 2XSOME reconstituted?

Bring both vials to room temperature. Inject or pipette the full 2SOME diluent (6 mL) into the 1SOME powder vial. Gently swirl — do not shake — until the powder fully dissolves. The mixed solution is ready for immediate use. Use within 24 hours of mixing; viability decreases rapidly thereafter.

Where can 2XSOME be applied?

Face, neck, scalp, and hands. Common protocols include topical application post-microneedling or post-laser, or shallow mesotherapy. Scalp delivery is for adjunctive hair-loss treatment. Always verify intradermal injection regulatory status in your jurisdiction before non-topical use.

How many sessions are typical?

1 set per session. 3 to 4 sessions spaced 2 to 4 weeks apart, with maintenance every 2 to 3 months. The 6 mL reconstituted volume is sufficient for full-face plus neck in a single session.

What is the source of the exosomes?

2XSOME uses stem-cell-derived exosomes — typically from adipose-derived mesenchymal stem cell (ADSC) culture supernatant or similar stem-cell platforms. Manufacturer materials describe them as 'multipotent cell exosomes' carrying regenerative signalling cargo for fibroblast and keratinocyte activation.

How much does 2XSOME Dual-Exosome cost?

2XSOME Dual-Exosome is priced at USD $59.00 per box (1 set of 1SOME powder + 2SOME diluent) on Fillersfairy, with wholesale pricing for licensed practitioners.

Source verification:→ Korean MFDS (regulatory authority)

Related Skin Boosters

Regulatory Notice. Korean MFDS-registered. CPNP (EU Cosmetic Products Notification Portal) and SCPN (Korean Skin Cosmetic Products Notification) certified. Manufactured under KGMP. Not approved for intradermal injection in most jurisdictions. This product is manufactured outside the United States; FDA approval status is product-specific. For licensed healthcare professionals only. Practitioners are responsible for verifying regulatory status of this product in their jurisdiction before clinical use. Not for retail sale. Pricing subject to change.