Quick Answer
ASCE Plus+ SRLV by ExoCoBio is a Korean dual-vial exosome system built around Rosa damascena (Damask rose) callus extracellular vesicles — plant-derived exosomes with vegan, non-animal origin. The lyophilized powder includes NAD+, retinol, ascorbic acid, glutathione, Copper Tripeptide-1, palmitoyl peptides, 19 amino acids, and 4 coenzymes. The 5 mL HA-buffered diluent reconstitutes the powder for topical-via-microchannel or mesotherapy delivery.
Why This Skinbooster Is Different
ASCE Plus+ SRLV uses Rosa damascena callus extracellular vesicles — plant-derived rather than the mammalian stem-cell-derived exosomes typical in the category. This addresses vegan-sourcing concerns and removes the mammalian-origin regulatory ambiguity. The activating diluent doubles as a multi-active concentrate (NAD+ for cellular energy, retinol for keratinocyte turnover, ascorbic acid for collagen biosynthesis, peptides for signalling). ExoCoBio is the same company behind ASCE+ exosomes generally and is FDA-listed for the SRLV kit (though not FDA-approved).
Mechanism of Action
Plant-Derived Exosome (Rosa damascena) + Multi-Active Matrix. Fibroblast-derived exosomes (30–150 nm vesicles) carry intercellular signalling cargo — proteins, lipids, miRNA. Once delivered to dermal cells, this cargo communicates regenerative signals: collagen synthesis cues, anti-inflammatory modulation, barrier repair. Application is typically post-procedure to amplify the skin's own repair response.
Frequently Asked Questions
What is ASCE Plus+ SRLV Exosome?
ASCE Plus+ SRLV is a Korean dual-vial exosome system from ExoCoBio. Vial 1 is a lyophilized powder containing Rosa damascena (Damask rose) callus extracellular vesicles plus NAD+, retinol, ascorbic acid, glutathione, Copper Tripeptide-1, palmitoyl peptides, 19 amino acids, and 4 coenzymes. Vial 2 is a 5 mL HA-buffered diluent. The two are mixed immediately before use.
What does 'SRLV' mean?
SRLV refers to the specific exosome composition in this kit — a proprietary ExoCoBio naming convention for the rose-derived vesicle blend. The kit is sometimes labelled 'SRLV-S' (Silver, Korean domestic market) or simply 'SRLV' (Gold, export market). The active formulation is consistent across versions.
Why use plant-derived (Rosa damascena) exosomes?
Three reasons. (1) Vegan/non-animal origin — addresses ethical and religious concerns about mammalian stem-cell-derived exosomes. (2) Lower regulatory ambiguity in many jurisdictions versus human or animal stem-cell exosomes. (3) Rosa damascena callus extracts have documented anti-inflammatory, antioxidant, and dermal-strengthening effects, providing a botanical regenerative profile.
How is ASCE Plus+ SRLV different from 2XSOME?
Both are dual-vial exosome systems. ASCE Plus+ SRLV uses plant-derived (Rosa damascena callus) exosomes with NAD+, retinol, peptides, and amino acids in the powder. 2XSOME (Maypharm) uses stem-cell-derived exosomes with hydrolyzed collagen + sodium DNA + Cu-tripeptide in the diluent. Different cell sources; ASCE Plus+ is vegan, 2XSOME is mammalian stem-cell-derived.
Is ASCE Plus+ SRLV FDA approved?
It is FDA-listed (NDC 72951-010) as a cosmetic but is not FDA-approved as a drug or biologic. The DailyMed entry includes the disclaimer that the product 'has not been found by FDA to be safe and effective.' Cosmetic registration is distinct from drug or device approval. Verify local jurisdiction regulations before clinical use.
How is ASCE Plus+ SRLV reconstituted?
Bring both vials to room temperature. Transfer the full 5 mL diluent into the 20 mg lyophilized powder vial. Gently swirl until fully dissolved — do not shake vigorously, as this can damage exosome integrity. Use the reconstituted solution within 24 hours. Best practice is to mix immediately before the procedure.
Why is NAD+ included?
NAD+ (nicotinamide adenine dinucleotide) is a critical co-factor for cellular energy production, DNA repair (PARP pathway), and sirtuin signalling. Skin NAD+ declines with age. Adding NAD+ to the exosome cocktail supports the metabolic substrate that downstream regenerative pathways depend on — an upstream complement to the exosome cargo.
How many sessions are typical?
3 to 4 sessions, spaced 2 to 4 weeks apart. Each session uses one full SRLV kit (powder + diluent reconstituted). Maintenance is every 2 to 3 months. Post-aggressive-procedure recovery protocols may use weekly sessions during the recovery phase.
Can ASCE Plus+ SRLV be combined with other treatments?
Yes — common combinations include post-fractional-laser application, post-RF-microneedling, post-PDRN-injection synergistic protocols, and adjunctive use during downtime recovery. The exosome cargo amplifies the regenerative response triggered by the primary procedure.
How much does ASCE Plus+ SRLV Exosome cost?
ASCE Plus+ SRLV Exosome is priced at USD $103.50 per kit (1 powder vial + 1 diluent vial) on Fillersfairy, with wholesale pricing for licensed practitioners.
Dr. Adrian Ross –
Just prepped my first session with the ASCE+ from my latest order and the quality is definitely there. The lyophilized powder dissolved perfectly into the activator without any clumping—I’ve had issues with other brands being a headache to mix, but this was a breeze. It’s so thin and smooth that using a 32G needle was effortless. It makes the whole process feel much more professional when the product behaves exactly how it’s supposed to.
Marcus Sterling –
I’ve spent way too much time cross-referencing different suppliers for ASCE+, and honestly, fillersfairy is the first place where the bulk pricing actually makes sense. I usually order 20 units at a time to keep my clinic stocked, and the 8% discount they give for that volume is huge for my margins. Most other sites have these hidden fees or higher base prices, but this was straightforward and clearly the best deal for the real deal.