Celosome Mid — Medium-Density HENM Filler for Mid-to-Deep Wrinkles & Liquid Facelift

Celosome Mid is ExCoBio’s medium-density variant — 24 mg/mL cross-linked HA + 0.3% lidocaine with HENM cross-linking and 8-phase purification. Engineered for mid-to-deep dermal placement: nasolabial folds, cheek augmentation, and liquid facelift protocols. 9–18 month durability. KFDA registered.

Celosome Mid Hyaluronic Acid Filler is manufactured by ExCoBio Co. Ltd., a South Korea-based medical device and pharmaceutical company established in 2017. The product is part of the Celosome dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · GMP certified.

Celosome Mid Hyaluronic Acid Filler contains 24 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using ExCoBio Co. Ltd.’s HENM + 8-Phase Purification technology. Phosphate-buffered saline at near-physiological pH carries the gel.

Per ExCoBio Co. Ltd.’s clinical data, Celosome Mid Hyaluronic Acid Filler delivers 9–18 months of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Mid to deep dermis placement typically delivers the longer end of the duration range.

Celosome Mid Hyaluronic Acid Filler is engineered for mid to deep dermis placement. The standard recommended needle is 27G, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.

Celosome Mid Hyaluronic Acid Filler regulatory status: KFDA registered · GMP certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.

Store Celosome Mid Hyaluronic Acid Filler between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.

No. Celosome Mid Hyaluronic Acid Filler uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).

Yes — layered protocols combining different fillers are standard aesthetic practice. Celosome Mid Hyaluronic Acid Filler can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.

Celosome Mid is the most versatile variant in the ExCoBio Celosome range — its medium cross-linking density supports the widest range of indications, from nasolabial folds and cheek augmentation to liquid facelift protocols and lip contouring. When practitioners are unsure between Soft (too light) and Strong (too firm) for a given indication, Mid is often the default starting point with sustained 9–18 month durability.