HyalDew All — MCL HA Filler for Deep Wrinkles & Facial Volumising

HyalDew All is BioPlus’s deep-grade variant — 20 mg/mL cross-linked HA + 0.3% lidocaine via patented MCL (Multi-staged Cross-Linking) 3-stage cross-linking technology. Ultrafine microbead structure for semi-solid gel consistency. Engineered for deep dermal placement: deep expression lines, face contouring, and volumising. Up to 12 months durability.

HyalDew All with Lidocaine is manufactured by BioPlus Co. Ltd., a South Korea-based medical device and pharmaceutical company established in 2010. The product is part of the HyalDew dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · CE marked · GMP certified.

HyalDew All with Lidocaine contains 20 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using BioPlus Co. Ltd.’s MCL (Multi-staged Cross-Linking) Technology technology. Phosphate-buffered saline at near-physiological pH carries the gel.

Per BioPlus Co. Ltd.’s clinical data, HyalDew All with Lidocaine delivers Up to 12 months of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Deep dermis placement typically delivers the longer end of the duration range.

HyalDew All with Lidocaine is engineered for deep dermis placement. The standard recommended needle is 25G, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.

HyalDew All with Lidocaine regulatory status: KFDA registered · CE marked · GMP certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.

Store HyalDew All with Lidocaine between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.

No. HyalDew All with Lidocaine uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).

Yes — layered protocols combining different fillers are standard aesthetic practice. HyalDew All with Lidocaine can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.

MCL is BioPlus’s patented 3-stage HA cross-linking technology used across the HyalDew range. The multi-staged process allows regulation of cross-linking rate and gel viscosity at each stage — producing four product variants (HyalDew Shine, Fine, Mid, All) with different cross-linking densities from a single base technology. The result: ultrafine microbead gel structure that integrates smoothly into tissue, semi-solid consistency that resists migration, and sustained 12-month durability supported by KFDA, GMP, and CE certifications.