Lipstar — Korean Lip Filler with Cross-Linked HA & Natural Anthocyanin Antioxidant
Lipstar is a Korean cross-linked hyaluronic acid lip filler manufactured by STARPHARMTEC in Seoul, formulated with natural anthocyanin antioxidant for UV protection and subtle lip pigment enhancement. The 1.2 mL pre-filled syringe carries 20% more volume than standard 1.0 mL lip fillers — enough for combined upper and lower lip treatment in a single session.
Manufacturer: STARPHARMTEC Co. Ltd., Seoul, South Korea (Dongdaemun-gu) · KFDA registered
Why Anthocyanin Makes Lipstar Different from Standard HA Lip Fillers
Most Korean lip fillers focus on volume retention alone. Lipstar’s formulation pairs cross-linked HA with anthocyanin — a flavonoid polyphenol with documented antioxidant activity 4–6 times higher than vitamin C. The result is a lip filler that adds volume and contributes to lip tissue protection.
Multi-Stage Cross-Linking
Hyaluronic acid is cross-linked using sequential stabilisation phases rather than single-step BDDE cross-linking. The result: more uniform gel structure and reduced residual BDDE — important for lip placement where tissue is thin and vascular.
Anthocyanin Antioxidant
Natural polyphenol from blueberries and black rice. Documented ORAC (oxygen radical absorbance capacity) is 4–6× higher than vitamin C. In lip tissue, anthocyanin contributes to natural lip pigmentation enhancement and protection against UV-induced oxidative damage.
1.2 mL Volume Advantage
20% more product per syringe than standard 1.0 mL lip fillers. Allows full upper + lower lip treatment in one syringe rather than two — reducing per-treatment cost and patient injection burden.
Lipstar Active Ingredients
Cross-Linked Hyaluronic Acid
Non-animal hyaluronic acid produced by bacterial fermentation, then cross-linked via STARPHARMTEC’s multi-stage stabilisation process. Cross-linking creates a more stable, durable gel matrix that resists rapid enzymatic breakdown in lip tissue.
Anthocyanin
A water-soluble flavonoid pigment naturally present in dark berries, black rice, and red cabbage. Documented antioxidant capacity 4–6× higher than vitamin C (ORAC scale). In the lip filler context, anthocyanin contributes to: (1) natural lip pigment enhancement, (2) protection against UV-induced free radical damage, and (3) anti-inflammatory effect at the injection site.
Phosphate Buffer
Phosphate-buffered saline at near-physiological pH carries the gel and reduces injection-site discomfort by approximating natural tissue pH.
Where Lipstar Is Used
Lip Volume Augmentation
Primary indication. 1.2 mL provides sufficient product for combined upper + lower lip body treatment in a single session.
Lip Border Definition
Vermillion border enhancement and cupid’s bow refinement. The HA gel structure supports defined lip contour without rigid projection.
Lip Hydration & Colour
HA’s water-binding capacity (up to 1,000× its weight in water) hydrates lip tissue. Anthocyanin contributes to natural lip pigment enhancement — patients commonly report subtle colour boost.
Perioral Fine Lines
Off-label use for smoker’s lines and lipstick lines around the mouth — though dedicated perioral filler variants may be preferred for this indication.
Lipstar vs Restylane Kysse vs Juvederm Volbella
| Feature | Lipstar | Restylane Kysse | Juvederm Volbella |
|---|---|---|---|
| Syringe Volume | 1.2 mL | 1.0 mL | 1.0 mL |
| Antioxidant Ingredient | Anthocyanin (natural polyphenol) | None | None |
| Cross-Linking Tech | Multi-stage HA stabilisation | OBT / XpresHAn™ | Vycross™ |
| Pigment Enhancement | Subtle from anthocyanin | None | None |
| Approval | KFDA (South Korea) | FDA + CE | FDA + CE |
| Origin | South Korea (STARPHARMTEC) | Sweden (Galderma) | USA (Allergan / AbbVie) |
| Distinctive Strength | Volume + antioxidant + pigment | Soft, flexible lip movement | Smooth fine-line correction |
↔ Swipe horizontally on mobile to view all columns
Comparison based on manufacturer published data. See our top dermal filler comparison guide for broader market context.
Lipstar Product Specifications
Manufacturer
- Brand: Lipstar
- Company: STARPHARMTEC Co. Ltd.
- Location: Dongdaemun-gu, Seoul, South Korea
- Audience: Licensed practitioners
Formula
- HA Source: Non-animal bacterial fermentation
- Cross-Linking: Multi-stage stabilisation
- Antioxidant: Anthocyanin (natural polyphenol)
- Carrier: Phosphate buffer pH 6.8–7.5
Packaging
- Syringe: 1 × 1.2 mL pre-filled
- Volume advantage: +20% vs standard 1.0 mL
- Use: Single-use sterile
- Last reviewed: May 2026
Storage & Approval
- Storage: 2–25 °C, do not freeze
- Shelf life: 24 months unopened
- Approval: KFDA registered
- FDA / CE: Not currently approved
Verify regulatory status at the official Korean MFDS database — nedrug.mfds.go.kr. For market pricing context, see our dermal filler pricing guide.
Lipstar — Frequently Asked Questions
What is Lipstar lip filler?
Lipstar is a Korean cross-linked hyaluronic acid lip filler manufactured by STARPHARMTEC in Seoul, formulated with natural anthocyanin antioxidant. Each syringe contains 1.2 mL — 20% more volume than the standard 1.0 mL lip filler format — and the gel is stabilised using a multi-stage cross-linking process for extended duration in lip tissue.
What is anthocyanin and why is it in Lipstar?
Anthocyanin is a water-soluble flavonoid polyphenol naturally present in dark berries, black rice, and red cabbage. Its documented antioxidant capacity (ORAC scale) is 4–6× higher than vitamin C. In Lipstar, anthocyanin contributes to three benefits beyond standard HA filler: protection against UV-induced free radical damage at the injection site, subtle natural lip pigment enhancement, and anti-inflammatory effect during post-procedure recovery.
Why is Lipstar 1.2 mL instead of the standard 1.0 mL?
Most lip fillers are supplied as 1.0 mL syringes — typically enough for one lip (upper OR lower) per session. Lipstar’s 1.2 mL format provides ~20% additional product, allowing practitioners to treat both upper and lower lips comprehensively in a single syringe. This reduces per-treatment cost for the patient and eliminates the need to open a second syringe for combined lip procedures.
How long does Lipstar last in the lips?
Per the manufacturer, Lipstar delivers sustained volume retention through the multi-stage cross-linking process. Most cross-linked HA lip fillers in this class provide 6–9 months in the lip body, with individual duration depending on patient metabolism, lip animation intensity, and injection technique. Touch-up sessions are recommended once volume softening becomes visible.
Does Lipstar contain lidocaine?
Lipstar’s standard formulation focuses on HA + anthocyanin without premixed lidocaine. Practitioners typically administer separate topical anaesthesia (EMLA cream or dental block) for lip procedures. If you require a premixed-lidocaine variant, confirm with the supplier whether Lipstar Lidocaine is available in your market.
Does the anthocyanin actually change lip colour?
Anthocyanin’s pigment effect in Lipstar is subtle — it is not a lip tint and does not replace lipstick. Patients commonly report a mild natural-looking colour enhancement (slightly more saturated lip pigment) rather than a dramatic visible colour change. The primary functional role of anthocyanin remains antioxidant protection; the pigment enhancement is a secondary cosmetic benefit.
Where is Lipstar manufactured?
Lipstar is manufactured by STARPHARMTEC Co. Ltd., a Korean medical device manufacturer based in Dongdaemun-gu, Seoul. The product is registered with the Korean Ministry of Food and Drug Safety (KFDA / MFDS). Registration details can be verified at the official MFDS pharmaceutical database at nedrug.mfds.go.kr.
Is Lipstar FDA approved or CE marked?
Lipstar is KFDA registered in South Korea. It is not currently FDA approved in the United States and CE marking status should be confirmed directly with STARPHARMTEC for the EU market. Buyers are responsible for verifying that import and clinical use are permitted in their jurisdiction before ordering.
How should Lipstar be stored at the clinic?
Store between 2 °C and 25 °C, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.
Can Lipstar be combined with other lip fillers or Botox in the same session?
Yes, layered protocols are common. Practitioners may use Lipstar for lip body volume in combination with a softer HA filler for vermillion border definition, or in conjunction with botulinum toxin around the perioral area for upper lip lines. Always wait the recommended interval between different injectable products and confirm biocompatibility per the manufacturer’s IFU.
Other Lip Fillers on Fillersfairy
Tesoro Rouge 1.1ml
BNC Global premium lip filler with 26 mg/mL HA + Vitamin B12 + natural pink tint. The strongest Korean alternative to Lipstar’s antioxidant positioning.
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Restylane Kysse
Galderma’s OBT/XpresHAn technology lip filler. FDA approved for lip augmentation and upper perioral wrinkles. Up to 12 months in lips.
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Restylane Lidocaine 1ml
The original NASHA-technology Restylane. FDA approved for lip enhancement with firmer projection than OBT-family alternatives.
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Read Before Clinical Use
Lipstar is a prescription medical device for use only by licensed aesthetic practitioners. Common reactions include injection-site bruising, swelling, redness, and tenderness — generally resolving within 3–7 days. Lip placement carries elevated bruising risk due to dense vascular supply. Like all hyaluronic acid dermal fillers, treatment carries rare but serious vascular complication risks — particularly important around the labial artery in the upper and lower lip vermillion. Practitioners with anatomical knowledge of facial vasculature and access to hyaluronidase for emergency dissolution are required. Anthocyanin is generally well-tolerated; patients with known berry or polyphenol allergies should be screened pre-procedure. Full contraindications, vascular complication protocols, aftercare, and emergency guidance are detailed on the dermal filler safety page.
Fillersfairy.com is a channel distributor and does not provide medical advice. This page is for informational purposes only and does not replace the manufacturer’s official Instructions for Use, which remains the authoritative source for clinical administration. Regulatory status varies by jurisdiction — buyers are responsible for verifying legal status before ordering. Last reviewed May 2026 against STARPHARMTEC manufacturer documentation.


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