Why this product is different
Liztox is manufactured by Humedix, part of the Huons Group — one of the Korean pharmaceutical companies that entered the domestic botulinum toxin market with a freeze-dried product. The freeze-drying process produces a visible white powder cake in the vial, distinct from vacuum-dried products. Liztox is positioned as a cost-efficient Korean botulinum toxin option for practitioners seeking alternatives to higher-priced international brands.
Mechanism of action
Botulinum toxin type A blocks acetylcholine release at the neuromuscular junction by cleaving SNAP-25, a SNARE complex protein essential for vesicle fusion at the motor nerve terminal. The targeted muscle receives no contraction signal and relaxes. Clinical effect wanes as new axon terminals sprout and restore neuromuscular signalling.
Specifications
Category
Botulinum Toxin Type A — Freeze-dried
Manufacturer
Humedix Co., Ltd. (Huons Group)
Country of origin
Republic of Korea
Strain
Proprietary working strain (not publicly disclosed)
Process
Freeze-drying (lyophilization)
Active ingredients
Clostridium botulinum toxin type A, 100 units per vial. Human serum albumin (stabiliser). Sodium chloride (tonicity adjuster). Humedix proprietary working strain.
Pack
1 vial × 100 units. Lyophilized white powder for reconstitution with 0.9% sterile saline before injection.
Storage (unopened)
Store at 2–8 °C, protected from light. Do not freeze.
Shelf life
36 months from manufacturing date (unopened)
After reconstitution
Use within 24 hours when stored at 2–8 °C after reconstitution.
Supplied to
Licensed healthcare professionals only
Shipping
Cold-chain (2–8 °C), insulated packaging
SKU
FF-TX-LIZTOX-100U
Common application zones
Application zones below are common indications for which botulinum toxin type A is used by practitioners. Specific dosing per zone is determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Glabellar lines (between the eyebrows)
Forehead lines (horizontal)
Lateral canthal lines (crow’s feet)
Masseter contouring (lower-face slimming)
Brow lift refinement
Mentalis muscle (chin)
Platysma bands (neck)
Hyperhidrosis (axillary)
Contraindications
Pregnancy and lactation
Active infection at the planned injection site
Known hypersensitivity to botulinum toxin, human albumin, or any excipient
Neuromuscular disorders (myasthenia gravis, Lambert-Eaton, ALS)
Concurrent aminoglycosides or other neuromuscular blockers
Bleeding disorders or anticoagulant therapy without medical clearance
Frequently asked questions
What is Liztox 100U?
Liztox 100U is a Korean botulinum toxin type A manufactured by Humedix Co., Ltd. (part of the Huons Group). Each single-use vial contains 100 units of lyophilized white powder, reconstituted with 0.9% sterile saline before injection. Liztox is freeze-dried.
Who manufactures Liztox?
Liztox is manufactured by Humedix Co., Ltd., a Korean pharmaceutical company within the Huons Group. Humedix produces Liztox at its Korean manufacturing facility. The Huons Group is an established Korean pharmaceutical holding company with multiple subsidiaries across pharmaceuticals and biologics.
Is Liztox freeze-dried or vacuum-dried?
Liztox is freeze-dried (lyophilized). After freeze-drying, a visible white powder layer remains in the vial. This is distinct from vacuum-dried botulinum toxins (e.g. Nabota) which can sometimes appear nearly empty — both processes are normal manufacturing methods for botulinum toxin type A.
How is Liztox different from Botulax?
Both are Korean freeze-dried botulinum toxin type A products from different manufacturers. Liztox (Humedix / Huons Group) uses Humedix’s working strain. Botulax (Hugel) uses Hugel’s proprietary CBFC26 strain. Choice between them depends on practitioner preference, clinical experience, and pricing.
How is Liztox different from Nabota?
Liztox (Humedix) is freeze-dried. Nabota (Daewoong) is vacuum-dried. After reconstitution, both produce clear botulinum toxin solutions, but the vial appearance differs (visible white powder vs nearly empty). Strains and manufacturers are different.
Where is Liztox 100U commonly applied?
Common aesthetic application zones include glabellar lines, forehead, lateral canthal lines, masseter contouring, brow lift refinement, mentalis, and platysma bands. Therapeutic uses include hyperhidrosis. Specific dosing per zone is determined by the treating practitioner based on individual anatomy and clinical judgment.
What is the reconstitution procedure?
Use 0.9% sterile saline (preservative-free). Inject the saline slowly down the inner vial wall — do not shake. Gently swirl to dissolve the lyophilized powder into a clear, colourless solution. Inspect visually for clarity before use. Manufacturer instructions and institutional protocol guide the specific saline volume.
What are the contraindications?
Pregnancy and lactation, active infection at the injection site, known hypersensitivity to botulinum toxin or excipients, neuromuscular disorders (myasthenia gravis, Lambert-Eaton, ALS), concurrent aminoglycosides or other neuromuscular blockers, and bleeding disorders / anticoagulants without medical clearance.
What is the storage requirement?
Store unopened vials at 2–8 °C, protected from light. Do not freeze. After reconstitution, the solution is typically used within 24 hours when stored refrigerated. Discard any unused reconstituted product per institutional protocol.
Does Liztox require cold-chain shipping?
Yes. Continuous cold-chain (2–8 °C) is required from manufacturer to clinic. Fillersfairy ships botulinum toxin products in insulated cold-chain packaging with refrigerants to maintain temperature during transit.
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