⚠ Product Type Notice — Atelocollagen, Not HA Filler
Manla Kar is an atelocollagen skin booster, not a hyaluronic acid dermal filler. Three key differences: (a) requires saline reconstitution at 1:1 ratio before use — it is not a ready-to-use prefilled syringe; (b) uses multi-injection or 4mm microneedle technique for skin regeneration, not bolus volumising; (c) does not include premixed lidocaine. Do not apply HA filler injection protocols to this product.
Side-By-Side
Manla Kar Atelocollagen Skin Booster vs Juvederm vs Restylane
| Feature |
Manla Kar |
Juvederm (Allergan) |
Restylane (Galderma) |
| HA Concentration |
N/A — Atelocollagen Product |
15–24 mg/mL |
20 mg/mL |
| Cross-Linking Tech |
Atelocollagen |
Vycross / Hylacross |
NASHA® / OBT |
| Lidocaine |
0.3% (premixed) |
0.3% (XC lines) |
0.3% (Lidocaine variants) |
| Duration |
12-18 months (collagen regeneration) |
6–24 months (varies) |
6–18 months (varies) |
| Origin |
South Korea (Medisance Co. Ltd.) |
USA (Allergan / AbbVie) |
Sweden (Galderma) |
| Established Since |
2017 |
2006 |
1996 |
↔ Swipe horizontally on mobile to view all columns
Comparison based on manufacturer published data. See our top dermal filler comparison guide for broader market context.
FAQs
Manla Kar Atelocollagen Skin Booster — Frequently Asked Questions
What is Manla Kar Atelocollagen Skin Booster?
Manla Kar is Medisance’s atelocollagen skin booster — NOT a hyaluronic acid filler. Atelocollagen has telopeptides enzymatically removed to eliminate immune-rejection antigenicity. Requires saline reconstitution (1:1 ratio) before use. Multi-injection or 4mm microneedle technique into the dermis or epidermis. Stimulates fibroblast collagen synthesis for skin regeneration — does NOT provide structural volumising like HA fillers.
Where is Manla Kar Atelocollagen Skin Booster manufactured?
Manla Kar Atelocollagen Skin Booster is manufactured by Medisance Co. Ltd., a South Korea-based medical device and pharmaceutical company established in 2017. The product is part of the Manla Kar dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · CE marked · GMP certified.
What is the HA concentration in Manla Kar Atelocollagen Skin Booster?
Manla Kar Atelocollagen Skin Booster contains N/A — Atelocollagen Product of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using Medisance Co. Ltd.’s High-Purity Atelocollagen (Telopeptide-Removed) technology. Phosphate-buffered saline at near-physiological pH carries the gel.
How long do Manla Kar Atelocollagen Skin Booster results last?
Per Medisance Co. Ltd.’s clinical data, Manla Kar Atelocollagen Skin Booster delivers 12-18 months (collagen regeneration) of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Dermis / epidermis (multi-injection) placement typically delivers the longer end of the duration range.
What is the recommended injection depth for Manla Kar Atelocollagen Skin Booster?
Manla Kar Atelocollagen Skin Booster is engineered for dermis / epidermis (multi-injection) placement. The standard recommended needle is 30G or 4mm microneedle, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.
Is Manla Kar Atelocollagen Skin Booster FDA approved or CE marked?
Manla Kar Atelocollagen Skin Booster regulatory status: KFDA registered · CE marked · GMP certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.
How should Manla Kar Atelocollagen Skin Booster be stored at the clinic?
Store Manla Kar Atelocollagen Skin Booster between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.
Does Manla Kar Atelocollagen Skin Booster contain animal-derived ingredients?
No. Manla Kar Atelocollagen Skin Booster uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).
Can Manla Kar Atelocollagen Skin Booster be combined with other dermal fillers in the same session?
Yes — layered protocols combining different fillers are standard aesthetic practice. Manla Kar Atelocollagen Skin Booster can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.
How is Manla Kar different from HA dermal fillers?
Manla Kar is a COLLAGEN product, NOT a hyaluronic acid filler. Critical differences: (1) Active ingredient is atelocollagen (pig-skin-derived, telopeptide-removed to eliminate antigenicity), not hyaluronic acid. (2) Requires reconstitution with saline at 1:1 ratio before use — it is NOT a ready-to-use prefilled syringe like HA fillers. (3) Mechanism is skin regeneration via fibroblast stimulation, not structural volumising. (4) Injection technique uses multi-point intradermal injection or 4mm microneedle, not bolus or linear threading. (5) Does NOT include premixed lidocaine. Practitioners should NOT use HA filler injection protocols for Manla Kar.
Important Safety Information
Read Before Clinical Use
Manla Kar Atelocollagen Skin Booster is a prescription medical device for use only by licensed aesthetic practitioners. Common reactions include injection-site bruising, swelling, redness, and tenderness — generally resolving within days. Like all hyaluronic acid dermal fillers, treatment carries rare but serious vascular complication risks. Contraindicated in patients with known hypersensitivity to hyaluronic acid or lidocaine, active skin infection at the treatment site, pregnancy, or breastfeeding. Full contraindications, vascular complication protocols, aftercare, and emergency guidance are detailed on the dermal filler safety page.
Read Full Dermal Filler Safety Information →
Manla Kar is a registered trademark of Medisance Co. Ltd.. Fillersfairy.com is a channel distributor and does not provide medical advice. This page is for informational purposes only and does not replace the manufacturer’s official Instructions for Use, which remains the authoritative source for clinical administration. Regulatory status varies by jurisdiction — buyers are responsible for verifying legal status before ordering. Last reviewed May 2026 against Medisance Co. Ltd. manufacturer documentation.
Chloe Smith –
This is genuinely the most painless filler I’ve ever used! With other brands, the burning sensation during injection was pure torture. Manla Kar’s pH balance is formulated so well, and combined with the ultra-fine needle, the comfort level is a 10/10. I focused on my lips and nasolabial folds. It spreads beautifully and doesn’t leave hard lumps like some other products. Also, it doesn’t give you that instantly swollen, fake look; it slowly integrates with your tissue. For anyone who dreads pain and wants a natural result, this is hands down the best choice. Highly recommend it—just look at my uploaded before/after video, it’s literally like two different faces!
Michelle Garcia –
I’ve had issues in the past with fillers leaving a weird, heavy feeling under my skin, but this one is completely different. Because it’s atelocollagen, it just melts right into my own tissue. A few days after treating my smile lines, I couldn’t even feel it in there, but the lift was obvious. Really impressed with the quality.
Sarah Johnson –
Skeptical at first since most collagens just sit on skin. But injecting 0.3ml weekly? My crow’s feet look airbrushed! Real talk – hydration claim checks out (my skin analyzer showed +28% vs their 32% claim), but you MUST follow the 1ml max/session rule. Pro-tip: Ice before injection!
Olivia Reynolds –
Been using Manla Kar in my clinic for 3 months – that 30G needle is a game-changer! Precise periosteum deposition means less swelling for clients. My patient Lisa (55yo) saw 19% density boost after 2 sessions.