Quick Answer
NCTF 135HA is the reference French aesthetic mesotherapy cocktail from FILLMED (formerly Filorga), supplied as 5 × 3 mL vials. The formulation contains 5 mg/mL non-crosslinked HA combined with 55 revitalizing ingredients — 12 vitamins, 24 amino acids, 6 coenzymes, 5 nucleic bases, 4 minerals, 2 antioxidants. The standard anti-aging protocol is one session per month for two months, then every two months.
Why This Skinbooster Is Different
NCTF 135HA is the gold-standard reference in the mesotherapy cocktail category — with the broadest published clinical literature and the longest practice track record. The 55-ingredient architecture is more comprehensive than most competitor cocktails. Its French (FILLMED) provenance and EU CE Class III status differentiate it from Korean-manufactured cocktails.
Mechanism of Action
Polyrevitalizing mesotherapy (non-crosslinked HA + nutrient cocktail). A multi-active concentrate is delivered through multiple superficial intradermal microinjections (~0.05–0.1 mL per point). Each component addresses a different aspect of dermal physiology — HA for hydration, vitamins/coenzymes for metabolism, amino acids/peptides for protein synthesis, PDRN where included for DNA-level repair signal.
Frequently Asked Questions
Why is it called NCTF 135HA?
NCTF stands for New Cellular Treatment Factor — FILLMED's branding for the polyrevitalizing complex. '135' refers to the formulation reference number in the FILLMED catalogue. 'HA' indicates the addition of hyaluronic acid (5 mg/mL non-crosslinked) to the base cocktail. FILLMED was formerly known as Filorga.
What exactly is in the 55-ingredient complex?
12 vitamins (A, B1–B9, C, E with optimized bioavailability), 24 amino acids (including hydroxyproline, glycine, proline for collagen synthesis), 6 coenzymes, 5 nucleic bases, 4 minerals (Mg, Na, K, Ca), and 2 antioxidants. The combination is designed to replicate physiological dermal nutrient composition.
Is the HA in NCTF 135HA crosslinked?
No. The 5 mg/mL HA is non-crosslinked, meaning it is free hyaluronic acid rather than the BDDE-modified gel found in dermal fillers. This makes NCTF 135HA a mesotherapy product (nutrient delivery) rather than a structural HA filler — the HA component here is one of 56 active ingredients, not the headline mechanism.
How is it injected?
Aesthetic mesotherapy technique: 30° needle angle, multiple micro-injections (0.05–0.1 mL per point) at 1 cm spacing into the superficial dermis. For the periocular area, reduce volume to ≤0.03 mL per point. Compatible with derma-roller and meso-gun for larger fields.
What is the standard protocol for anti-aging treatment?
FILLMED recommends one session per month for two months, then one session every two months. For mature or strongly photo-damaged skin, a longer initial course may be appropriate. Maintenance dosing every 3–6 months sustains the benefit.
How is it different from Korean mesotherapy cocktails (Puri Heal Glow, Cytocare)?
NCTF 135HA is the French gold-standard reference — broadest clinical literature, EU CE Class III, FILLMED manufacturer track record. Korean cocktails (Puri Heal Glow) often include additional ingredients such as PDRN, named peptides, and hydrolyzed collagen. Both are valid; selection is based on patient profile and practitioner preference.
Can it be combined with FILLMED fillers?
Yes — this is FILLMED's recommended combination protocol. NCTF 135HA is used as the foundation skin quality treatment; structural correction is added with FILLMED HA fillers (Art Filler range) as needed. Sessions can be staged or, with experienced practitioners, combined same-day in different anatomical planes.
Are there contraindications?
Standard contraindications: pregnancy and lactation (precautionary), autoimmune disease (FILLMED contraindicates), shellfish/protein allergy (the formulation contains plant and protein components), known hypersensitivity to any component. Patient history and contraindication review are essential before the first session.
Is it suitable for the scalp and hair loss?
Yes — NCTF 135HA is widely used in trichology mesotherapy for hair density support and follicle nutrition. Injection technique is adapted for the scalp anatomy. This is an off-label aesthetic use; practitioner judgement applies.
What downtime is expected?
Standard mesotherapy: papules at injection points resolve within 6–24 hours, mild erythema settles within a day. The product label states 'no eviction' (no social downtime). Patients can resume normal activity the same day.
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