Radiesse 1.5ml Injectable Implant
(P040024/S14) opaque dermal filler. Strictly for B2B clinical procurement and administration by licensed medical professionals.
Composition Specifications
Active Agent: 30% synthetic Calcium Hydroxylapatite (CaHA).
Microsphere Diameter: Uniform 25-45 microns (μm).
Carrier Matrix: 70% aqueous gel base (Sodium Carboxymethylcellulose, Glycerin, Sterile Water).
Anesthetic: 0.3% integral Lidocaine Hydrochloride (reduces pain during injection).
Rheological Profile
Elastic Modulus (G’): Extremely high G’ rating provides superior structural support and resistance to dynamic facial forces.
Complex Viscosity (η*): High viscosity prevents post-implantation product migration and maintains sharp contour definitions.
Degradation: Phagocytosis breaks down CMC carrier first, leaving CaHA scaffold. CaHA degrades safely into systemic calcium and phosphate ions over 12-18 months.
Biostimulatory Mechanism of Action
Immediate Volumization
Upon injection, the CMC gel carrier immediately occupies target subcutaneous voids, establishing 1:1 volume restoration. This provides direct mechanical lifting capacity for moderate-to-severe folds.
Neocollagenesis
As macrophages resorb the CMC gel (weeks 4-12), the suspended CaHA microspheres act as a scaffold. This stimulates localized fibroblastic activity, resulting in up to a 68% increase in endogenous Type I and Type III collagen.
Clinical Delivery Protocol
Injection Plane: Subdermal or Deep Dermis. Avoid superficial dermis to prevent nodule formation.
/: Use provided 25G-27G standard or equivalent atraumatic.
Storage Parameters: Controlled room temperature 15°C to 25°C (59°F to 77°F). Do not freeze.
Package Yield: One 1.5cc (ml) pre-filled. Single-patient use strictly enforced.
Absolute Contraindications
Contraindicated in patients with severe allergies manifested by a history of anaphylaxis, multiple severe allergies, or hypersensitivity to lidocaine or amide-type local anesthetics. Not indicated for periocular, glabellar, or lip augmentation.
*Merz Aesthetics, Merz Pharma GmbH & Co. KGaA. Refer to official Instructions for Use (IFU) prior to application. Results depend on anatomical assessment and precise injection technique. RX ONLY.

Dr. Emily Carter –
As a dermatologist, I’ve used Radiesse for years, and this 1.5ml filler is a game-changer for mid-face volume loss. The CaHA microspheres give immediate lift while stimulating collagen—I’ve seen results last 16+ months in my patients.
Sarah Johnson –
Okay, I was nervous trying fillers, but Radiesse blew me away,got it for my nasolabial folds. The swelling lasted 2 days, but by week 2, my skin looked plumper naturally. Not a ‘frozen’ look at all.