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Sculptra® (2 Vials)

$378.00

Sculptra® (2 vials) — Poly-L-lactic acid (PLLA-SCA) collagen stimulator. FDA-approved (2009 aesthetic; 2023 cheek wrinkles). The first and original FDA-approved PLLA biostimulator, results up to 2 years. Lyophilized powder for reconstitution. For licensed healthcare professionals only.

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PLLA Collagen Biostimulator
Sculptra® (2 Vials)

Country of origin  ·  United States / France

Process
PLLA microspheres
Material
PLLA microparticles (PLLA-SCA)

Sculptra® is the first and original FDA-approved poly-L-lactic acid (PLLA) collagen stimulator. Supplied as a lyophilized powder for reconstitution, it stimulates your own collagen to smooth wrinkles and restore volume, with natural results lasting up to two years. This is the 2-vial pack.

About this product · FDA-approved

Sculptra® is FDA-approved in the United States. It was first approved for aesthetic use in 2009 (correction of nasolabial fold contour deficiencies and other facial wrinkles) and received an expanded label in 2023 for the correction of fine lines and wrinkles in the cheek area. It is the first and original FDA-approved poly-L-lactic acid (PLLA) collagen stimulator and is available in more than 40 countries.

Why choose Sculptra

·
FDA-approved PLLA — the first and original FDA-approved PLLA collagen stimulator
·
Biostimulator, not a filler — stimulates your own collagen; results up to 2 years
·
Lyophilized powder — reconstitute before use; optional lidocaine per current label
·
2-vial pack — available in more than 40 countries

How Sculptra stimulates collagen

After injection into the deep dermis or subcutis, the PLLA microparticles prompt fibroblasts to produce new type I and III collagen, rebuilding the skin’s scaffold over weeks to months. The PLLA is then broken down by hydrolysis and metabolised, while the new collagen remains — so volume builds gradually and looks natural.

Sculptra specifications

Category
PLLA Collagen Biostimulator
Country of origin
United States / France
Material
PLLA microparticles (PLLA-SCA)
Form
Lyophilized PLLA microspheres for reconstitution
Composition
Poly-L-lactic acid (PLLA-SCA), with sodium carboxymethylcellulose and non-pyrogenic mannitol; supplied as lyophilized powder for reconstitution
Pack
2 vials × lyophilized PLLA powder
Storage
Store at room temperature (below 25 °C). Do not freeze.
Shelf life
Per manufacturer labelling (unopened)
After reconstitution
Reconstitute per the official instructions for use; the current label permits higher dilution, immediate-use reconstitution, and optional addition of lidocaine.
Supplied to
Licensed healthcare professionals only
SKU
FF-PLLA-SCULPTRA-2V

Sculptra treatment areas

The areas below are commonly treated with this category of product by practitioners. Suitability, technique, and dosing for any given area are determined by the treating practitioner based on individual patient anatomy and clinical judgment.

Nasolabial folds (smile lines)
Cheek and full-cheek wrinkles
Midface and temporal volume loss
Marionette lines
Overall skin quality, firmness, and glow
Chin and jawline contour support

Contraindications

Pregnancy and lactation
Active infection, inflammation, or skin lesions at or near the intended treatment area
Known hypersensitivity to any component of the product
History of keloid formation or hypertrophic scarring
Bleeding disorders or anticoagulant therapy without appropriate clearance
Active autoimmune or connective tissue disease (relative — at practitioner discretion)

Sculptra — frequently asked questions

What is Sculptra®?

Sculptra® is an injectable poly-L-lactic acid (PLLA) collagen stimulator. It is supplied as a lyophilized powder that is reconstituted before injection and works by stimulating the skin’s own collagen production to smooth wrinkles and improve skin quality over time.

Is Sculptra FDA-approved?

Yes. Sculptra is FDA-approved in the United States. It was first approved for aesthetic use in 2009 and received an expanded label in 2023 for correction of fine lines and wrinkles in the cheek area. It is the first and original FDA-approved PLLA collagen stimulator.

Is Sculptra widely available?

Sculptra is FDA-approved in the United States and is available in more than 40 countries.

How long do results last?

Sculptra provides gradual, natural-looking results that can last up to two years, according to the manufacturer. Because it stimulates the body’s own collagen, the improvement develops over a treatment course rather than immediately.

How is Sculptra different from a hyaluronic acid filler?

A hyaluronic acid (HA) filler adds immediate volume and is reversible with hyaluronidase. Sculptra is a biostimulator that works by inducing new collagen over time; its results appear gradually and are not reversible with hyaluronidase.

How many sessions are typical?

PLLA collagen stimulators such as Sculptra are generally administered as a series of sessions, with the exact number and spacing determined by the treating practitioner based on individual goals and response. Treatment planning is at the practitioner’s discretion.

How is Sculptra reconstituted?

Sculptra is supplied as a lyophilized powder and reconstituted before use. The current FDA-approved label permits higher dilution, immediate-use reconstitution, and the optional addition of lidocaine. Practitioners should follow the official instructions for use.

How should Sculptra be stored?

Store unopened vials at room temperature per the manufacturer labelling. Do not freeze.

How does Sculptra compare to a Korean PLLA such as Olidia?

Sculptra and Korean PLLA stimulators such as Olidia share the same biological mechanism (PLLA-induced collagen stimulation). Sculptra is the FDA-approved original; Korean brands are MFDS-approved and often CE-marked, with differing particle specifications and composition. Brand selection is at the practitioner’s discretion.

Related PLLA / PCL / CaHA products

PLLA Biostimulator
Olidia® PLLA 365mg
Korean PLLA stimulator
Olidia® PLLA 365mg
PDLLA Biostimulator
Powerfill 1000mg
Korean PDLLA stimulator
Powerfill 1000mg
CaHA Biostimulator
Radiesse 1×1.5ml
FDA-approved CaHA
Radiesse 1×1.5ml
PDO Biostimulator
Rejubella 300mg
Korean PDO stimulator
Rejubella 300mg
Regulatory Notice. Manufactured in United States / France. This is an FDA-approved collagen-stimulating injectable for use by licensed healthcare professionals only. Practitioners are responsible for verifying the regulatory status of this product in their jurisdiction before clinical use, including any requirements for import, possession, and administration. Not for retail sale. Pricing subject to change. Last reviewed June 12, 2026.

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