Country of origin · United States / France
Sculptra® is the first and original FDA-approved poly-L-lactic acid (PLLA) collagen stimulator. Supplied as a lyophilized powder for reconstitution, it stimulates your own collagen to smooth wrinkles and restore volume, with natural results lasting up to two years. This is the 2-vial pack.
Sculptra® is FDA-approved in the United States. It was first approved for aesthetic use in 2009 (correction of nasolabial fold contour deficiencies and other facial wrinkles) and received an expanded label in 2023 for the correction of fine lines and wrinkles in the cheek area. It is the first and original FDA-approved poly-L-lactic acid (PLLA) collagen stimulator and is available in more than 40 countries.
Why choose Sculptra
How Sculptra stimulates collagen
After injection into the deep dermis or subcutis, the PLLA microparticles prompt fibroblasts to produce new type I and III collagen, rebuilding the skin’s scaffold over weeks to months. The PLLA is then broken down by hydrolysis and metabolised, while the new collagen remains — so volume builds gradually and looks natural.
Sculptra specifications
Sculptra treatment areas
The areas below are commonly treated with this category of product by practitioners. Suitability, technique, and dosing for any given area are determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Contraindications
Sculptra — frequently asked questions
Sculptra® is an injectable poly-L-lactic acid (PLLA) collagen stimulator. It is supplied as a lyophilized powder that is reconstituted before injection and works by stimulating the skin’s own collagen production to smooth wrinkles and improve skin quality over time.
Yes. Sculptra is FDA-approved in the United States. It was first approved for aesthetic use in 2009 and received an expanded label in 2023 for correction of fine lines and wrinkles in the cheek area. It is the first and original FDA-approved PLLA collagen stimulator.
Sculptra is FDA-approved in the United States and is available in more than 40 countries.
Sculptra provides gradual, natural-looking results that can last up to two years, according to the manufacturer. Because it stimulates the body’s own collagen, the improvement develops over a treatment course rather than immediately.
A hyaluronic acid (HA) filler adds immediate volume and is reversible with hyaluronidase. Sculptra is a biostimulator that works by inducing new collagen over time; its results appear gradually and are not reversible with hyaluronidase.
PLLA collagen stimulators such as Sculptra are generally administered as a series of sessions, with the exact number and spacing determined by the treating practitioner based on individual goals and response. Treatment planning is at the practitioner’s discretion.
Sculptra is supplied as a lyophilized powder and reconstituted before use. The current FDA-approved label permits higher dilution, immediate-use reconstitution, and the optional addition of lidocaine. Practitioners should follow the official instructions for use.
Store unopened vials at room temperature per the manufacturer labelling. Do not freeze.
Sculptra and Korean PLLA stimulators such as Olidia share the same biological mechanism (PLLA-induced collagen stimulation). Sculptra is the FDA-approved original; Korean brands are MFDS-approved and often CE-marked, with differing particle specifications and composition. Brand selection is at the practitioner’s discretion.

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