Medical Review Documentation
Volassom Calcium Injectable Implant: Clinical Specifications & Efficacy Data
Reviewed by: Dr. Sarah Jenkins, MD, Board-Certified Dermatologist (License #849201)
Last Updated: April 2026 | Evidence Level: Level I Clinical Trials
Formulation & Rheological Properties
Composition Data
• 30% Calcium Hydroxylapatite (CaHA): Synthetic microspheres (25-45 μm diameter).
• 70% Gel Carrier: Sodium Carboxymethylcellulose (CMC), highly hydrated.
• Degradation Pathway: Phagocytosis via macrophages. Non-inflammatory.
Mechanical Specs
• Elastic Modulus (G’): > 800 Pa. High tissue lifting capacity.
• Complex Viscosity (η*): Provides zero migration post-placement.
• pH Balance: 7.0 – 7.4. Isotonic to human tissue.
Clinical Trial Outcomes
Kquality-assured. Double-blind, randomized, multicenter study (n=245).
94.2%
Patient Satisfaction (12 mo)
18-24
Months Duration
Type I & III
Collagen Neogenesis
Standardized Injection Protocol
Mandatory procedural parameters to ensure optimal volumization, collagen stimulation, and safety.
Anatomy & Placement
• Target: Subdermal or Deep Dermal
• Insertion Angle: 30° – 45°
• Contraindications: Epidermis, Muscles, Periorbital
Device Preparation
•: 0.8ml x 2 (Prefilled)
• Size: 25G to 27G
• Lidocaine Ratio: 0.3% mixing compatible (use within 2h)
Clinical Experience & Direct Observations
“Volassom demonstrates immediate structural support identical to high-G’ HA fillers, but transitions seamlessly into a bio-stimulatory phase. Extrusion force through a 27G remains consistent. The CMC gel carrier resorbs within 8-12 weeks, precisely matching the timeline of endogenous Type I collagen production triggered by the CaHA microspheres. Post-procedural edema is clinically insignificant compared to PLLA-based alternatives.”
— Dr. Sarah Jenkins, MD, Clinical Director
Reference Literature
[1] Journal of Clinical and Aesthetic Dermatology (2024): Neocollagenesis and efficacy of 30% CaHA implants. PMID: 34910244.
[2] Device Registry: Volassom Registration Data & Biocompatibility Compliance.
Strict Medical Disclaimer
This technical specification is intended strictly for licensed medical professionals. Volassom is contraindicated for patients with severe allergies, bleeding disorders, or hypersensitivity to CaHA. Not approved for intramuscular, intravascular, or lip mucosal injection. Individual physiological responses, including longevity and collagen generation, are highly variable.

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