How Olidia stimulates collagen
After injection into the deep dermis or subcutis, the PLLA microparticles prompt fibroblasts to produce new type I and III collagen, rebuilding the skin’s scaffold over weeks to months. The PLLA is then broken down by hydrolysis and metabolised, while the new collagen remains — so volume builds gradually and looks natural.
Olidia specifications
Category
PLLA Collagen Biostimulator
Country of origin
Republic of Korea
Material
PLLA microspheres 40–63µm
Form
Lyophilized PLLA microspheres for reconstitution
Composition
Poly-L-lactic acid (PLLA) 150 mg; mannitol 125 mg; sodium carboxymethylcellulose (CMC) 90 mg — 365 mg total lyophilized powder per vial
Pack
1 vial × 365 mg lyophilized PLLA powder
Storage
Store at room temperature below 30 °C, protected from direct sunlight. Do not freeze.
Shelf life
36 months from date of manufacture (unopened)
After reconstitution
Reconstitute with sterile water or saline; use the reconstituted suspension per the practitioner’s standard protocol.
Supplied to
Licensed healthcare professionals only
SKU
FF-PLLA-OLIDIA-365
Olidia treatment areas
The areas below are commonly treated with this category of product by practitioners. Suitability, technique, and dosing for any given area are determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Nasolabial folds (smile lines)
Cheek and midface volume loss
Temporal (temple) hollowing
Marionette lines and jawline definition
Overall skin firmness and texture improvement
Dorsal hand volume restoration
Contraindications
Pregnancy and lactation
Active infection, inflammation, or skin lesions at or near the intended treatment area
Known hypersensitivity to any component of the product
History of keloid formation or hypertrophic scarring
Bleeding disorders or anticoagulant therapy without appropriate clearance
Active autoimmune or connective tissue disease (relative — at practitioner discretion)
Olidia — frequently asked questions
What is Olidia® PLLA 365mg?
Olidia® PLLA is a Korean collagen-stimulating injectable based on poly-L-lactic acid (PLLA). Each vial contains 365 mg of lyophilized powder — 150 mg PLLA microspheres plus mannitol (125 mg) and carboxymethylcellulose (90 mg). It is reconstituted before injection and works by stimulating the skin’s own collagen production.
Where is Olidia made?
Olidia is made in South Korea. It is an approved medical device of the Korean Ministry of Food and Drug Safety (MFDS) and carries CE marking.
Is this the Korean domestic version?
Yes. This is the Korean domestic-market edition of Olidia — the same product supplied to clinics and hospitals inside South Korea, from the same manufacturer source, with identical composition. Korean-language packaging may differ from export-relabelled editions, but the formulation is the same.
Is Olidia FDA-approved?
Olidia is approved by the Korean MFDS and is CE-marked; it is not a US FDA-approved product. Poly-L-lactic acid as a raw material has a long history of use in FDA-cleared medical devices, but that is a separate matter from the finished Olidia product’s regulatory status. Practitioners should verify the product’s status in their own jurisdiction before use.
How is Olidia different from a hyaluronic acid filler?
A hyaluronic acid (HA) filler adds immediate volume by occupying space in the tissue and is reversible with hyaluronidase. Olidia is a biostimulator: it does not rely on the material itself for volume but instead stimulates the body to produce new collagen over time, so results appear gradually and are not reversible with hyaluronidase.
How does Olidia compare to Sculptra?
Both Sculptra and Olidia are poly-L-lactic acid (PLLA) collagen stimulators that work by the same biological mechanism. Sculptra is FDA-approved in the United States. Olidia is a Korean MFDS-approved, CE-marked product. Composition and particle specifications differ between the two brands.
What is the particle size and why does it matter?
Olidia’s PLLA microparticles measure 40–63 µm. This range is large enough to avoid being cleared by dermal macrophages or passing through capillary walls, but small enough to be injected through fine needles. Uniform particle size also supports smoother, more even suspension.
How should Olidia be stored?
Store unopened vials at room temperature below 30 °C, away from direct sunlight. Do not freeze. Shelf life is 36 months from the date of manufacture.
Who should use Olidia?
Olidia is a professional medical device intended for reconstitution and injection by licensed healthcare professionals trained in PLLA-based collagen stimulators, in accordance with local regulations and the official instructions for use.
What vial sizes are available?
Olidia is produced in 365 mg, 240 mg (243.4 mg), and 120 mg (121.7 mg) vial sizes. This listing is the 365 mg vial.
Zephyr Vance –
Honestly, the Vitamin B12 tint in this is a total game changer. I used it with my microneedling pen and within two days, my lips had this gorgeous, natural rosy flush that doesn’t wash off. It’s perfect if you hate the heavy, fake look of traditional fillers but just want your lips to look alive and deeply hydrated.
Vivian Chen –
After having kids, my face looked so sunken and tired. A friend recommended Olidia. After the initial swelling went down, I thought it hadn’t worked—but don’t panic, that’s just how PLLA works. I did two sessions, and now six months later, my cheeks are plump and my skin texture is amazing. It’s not an “instant fix,” but since it builds your own collagen, the “expensive” look it gives is something regular fillers just can’t match.