Biomimetic Formulation

Net Weight: 365mg / Lyophilized

Active Agent: 150mg Poly-L-Lactic Acid (PLLA)

Osmotic Stabilizer: 125mg Mannitol

Suspension Agent: 90mg Sodium Carboxymethylcellulose

Particle Morphology

Diameter Range: 40-63μm (Macrophage phagocytosis avoidance threshold)

Structure: Porous, spherical microparticles

pH Balance: 6.8 – 7.4

Degradation Profile: 100% Biodegradable via hydrolysis into CO₂ and H₂O.

2022 Multicenter Study

Satisfaction Rate: 82% at 24-month follow-up.

Collagen Yield: Stimulates Type I and Type III collagen synthesis. Peak deposition at 6-8 weeks.

Adverse Events: 0.2% nodule formation rate (dependent on dilution/massage protocol).

Medical Indications

• Nasolabial folds (WSRS Grade 3-4)

• Temporal and malar volume deficit

• Dorsal hand soft tissue rejuvenation

• Sub-dermal tissue restoration (excluding periocular/lip zones)

Reconstitution Protocol

Diluent: 7ml Sterile Water for Injection (SWFI) + 2ml Lidocaine (2%).

Hydration Time: Minimum 2 hours (24 hours recommended).

Regimen: 3 sessions at 4-6 week intervals. 3ml administered per session.

Restricted Medical Device Notice

Sale and administration of Olidia® PLLA are strictly limited to licensed medical professionals. Subdermal injection requires mandatory post-treatment massage (5-5-5 rule). Manufacturer assumes zero liability for unlicensed administration, off-label application, or vascular occlusion events resulting from improper plane injection.