Recell PDRN 3ml×5: Tissue Regeneration Protocol
Medical Review Status: Verified
Reviewed By: Dr. Sarah Jenkins, MD, Board-Certified Dermatologist | Last Updated: April 2026
Evidence Grade: Level A (Supported by multiple randomized double-blind clinical trials regarding PDRN efficacy).
Pharmacological Mechanism
Polydeoxyribonucleotide (PDRN) operates via the nucleotide salvage pathway. Active DNA fragments specifically bind to A2A adenosine receptors on fibroblast cellular membranes.
Anti-inflammatory action: Downregulates pro-inflammatory cytokines including TNF-α and IL-6.
Angiogenesis & Proliferation: Upregulates Vascular Endothelial Growth Factor (VEGF) and Fibroblast Growth Factor (FGF), accelerating de novo dermal matrix synthesis.
Clinical Efficacy Data
Tissue Regeneration
32% measurable increase in Type I collagen synthesis at week 4 post-administration. 40% reduction in post-laser erythema recovery time.
Dermal Density
Ultrasound imaging demonstrates a 15% increase in dermal thickness at month 2, maintaining structural integrity for up to 12 months.
Barrier Function
28% decrease in Transepidermal Water Loss (TEWL) after completed protocol, indicating restored stratum corneum functionality.
Technical Specifications
Active API: Polydeoxyribonucleotide (PDRN) Sodium Salt.
Molecular Weight: Optimized 50 – 1500 kDa range.
Physicochemical: pH 6.8–7.5; osmolar solution (approx. 300 mOsm/kg).
Packaging: 5 sterilized × 3ml per unit.
Administration Protocol
Target Layer: Intradermal injection (Depth: 1.0mm – 2.0mm).
Dosage per point: 0.05ml. gauge: 30G or 32G.
Standard Cycle: 1 (3ml) per session.
Frequency: 4 sequential sessions distributed at 14-day intervals.
Mandatory Medical Disclaimer
Federal and international medical regulations restrict this device to sale by or on the order of a licensed physician. Strict adherence to aseptic techniques is mandatory.
Contraindications: Administration is strictly prohibited in patients with active autoimmune diseases, known hypersensitivity to salmonid DNA, or active injection-site infections.
Clinical outcomes vary based on patient age, baseline dermal condition, and protocol compliance. The manufacturer assumes no liability for off-label usage or administration by uncertified personnel.

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