Hyalmass Aqua Exosome: Triple-Active Skin Booster

June 29, 2026
12:00 am

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TITLE TAG: Hyalmass Aqua Exosome: HA + PDRN + Exosome Triple-Active Guide
META DESCRIPTION: Hyalmass Aqua Exosome combines 1% HA, 0.01% PDRN and high-concentration exosomes in one pre-mixed syringe. No reconstitution. 10-syringe box for high-volume clinics.
SLUG: /hyalmass-aqua-exosome-guide/
CATEGORY: Skin Boosters
FOCUS KEYPHRASE: hyalmass aqua exosome
CANONICAL: https://fillersfairy.com/hyalmass-aqua-exosome-guide/
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<h1>Hyalmass Aqua Exosome: The Triple-Active Skin Booster That Combines HA, PDRN and Exosomes in One Syringe</h1>

<p><em>Written by FillersFairy Editorial · Reviewed by FillersFairy Clinical Team · Last updated: June 29, 2026</em></p>

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<h2 style="margin-top:0;">Quick Answer</h2>
<p><strong>Hyalmass Aqua Exosome is the first skin booster to combine three regenerative actives in a single pre-mixed syringe:</strong> 1% hyaluronic acid for immediate hydration, 0.01% salmon-DNA-derived PDRN for fibroblast activation, and billions of exosome particles per syringe for intercellular regenerative signalling. Manufactured by Maypharm (Beauty Factory, South Korea) under GMP standards and launched globally in December 2024, it comes in a 10-syringe box — ready to use with no reconstitution needed. For clinics, this means three treatment mechanisms in one product, one application step and one inventory item.</p>
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<figure class="wp-block-image size-full"><img src="https://fillersfairy.com/wp-content/uploads/2026/06/hyalmass-hero.png" alt="Hyalmass Aqua Exosome — HA PDRN exosome triple-active pre-mixed syringe" class="wp-image-20706"/></figure>
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<nav style="background:#f5f5f5; border-radius:8px; padding:20px; margin:28px 0;">
<p style="font-weight:bold; margin-top:0;">In This Guide</p>
<ol>
<li><a href="#why-triple">Why Three Actives in One Syringe Matters</a></li>
<li><a href="#specs">Product Specifications</a></li>
<li><a href="#how-works">How the Triple-Active Formula Works</a></li>
<li><a href="#vs-asce">Hyalmass vs ASCE+ SRLV: Different Exosome Approaches</a></li>
<li><a href="#protocol">Treatment Protocol</a></li>
<li><a href="#clinic">Why Clinics Are Switching to Triple-Active Boosters</a></li>
<li><a href="#faq">Frequently Asked Questions</a></li>
</ol>
</nav>

<h2 id="why-triple">Why Three Actives in One Syringe Matters</h2>

<p>Traditional skin booster protocols layer products: an HA booster for hydration, then a PN or PDRN injection for collagen stimulation, then exosomes for regenerative signalling. Three products, three applications, three procurement decisions.</p>

<p>Hyalmass Aqua Exosome compresses all three into a single syringe. The immediate clinical advantage is obvious — one product addresses hydration, collagen stimulation and cellular regeneration simultaneously. But the operational advantage is equally important: one inventory item, one application step per patient and one procurement relationship instead of three.</p>

<p>For high-volume clinics treating 10+ skin booster patients per day, the time savings and simplification are substantial.</p>

<h2 id="specs">Product Specifications</h2>

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<figure class="wp-block-image size-full"><img src="https://fillersfairy.com/wp-content/uploads/2026/06/hyalmass-specs.png" alt="Hyalmass triple-active Venn diagram — HA, PDRN, exosomes" class="wp-image-20707"/></figure>
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<div style="overflow-x:auto;">
<table style="width:100%; border-collapse:collapse; min-width:400px;">
<tr style="background:#1a237e; color:white;">
<th style="padding:12px; text-align:left;">Parameter</th>
<th style="padding:12px; text-align:left;">Specification</th>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Manufacturer</td>
<td style="padding:10px;">Maypharm Co., Ltd. / Beauty Factory (South Korea), GMP compliant</td>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Active Ingredients</td>
<td style="padding:10px;">1% Hyaluronic Acid + 0.01% PDRN (salmon DNA) + Exosomes (Billions of exosome particles per syringe)</td>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Syringe Volume</td>
<td style="padding:10px;">2.5 mL per prefilled syringe</td>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Pack Size</td>
<td style="padding:10px;">10 syringes per box (25 mL total volume)</td>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Format</td>
<td style="padding:10px;">Pre-mixed, ready-to-use. No reconstitution or mixing required.</td>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Application Methods</td>
<td style="padding:10px;">Mesotherapy injection, microneedling glide, meso gun, meso jet, topical</td>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">CE Certification</td>
<td style="padding:10px;">Hyalmass line CE certified (April 2023)</td>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Shelf Life</td>
<td style="padding:10px;">36 months from manufacturing</td>
</tr>
<tr>
<td style="padding:10px;">Global Launch</td>
<td style="padding:10px;">December 30, 2024</td>
</tr>
</table>
</div>

<p><em>Sources: Maypharm official product documentation, TradeKorea listing, Personal Care Insights product launch coverage.</em></p>

<h2 id="how-works">How the Triple-Active Formula Works</h2>

<p>Each of the three actives addresses a different layer of skin health:</p>

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<table style="width:100%; border-collapse:collapse; min-width:500px;">
<tr style="background:#1a237e; color:white;">
<th style="padding:12px; text-align:left;">Active</th>
<th style="padding:12px; text-align:center;">Concentration</th>
<th style="padding:12px; text-align:left;">What It Does</th>
<th style="padding:12px; text-align:left;">When You See It</th>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px; font-weight:bold;">Hyaluronic Acid</td>
<td style="padding:10px; text-align:center;">1%</td>
<td style="padding:10px;">Binds up to 1,000× its weight in water. Provides immediate deep dermal hydration. Improves skin plumpness and glow.</td>
<td style="padding:10px; font-weight:bold; color:#2e7d32;">Immediately — Day 1</td>
</tr>
<tr style="border-bottom:1px solid #eee; background:#f8f9fa;">
<td style="padding:10px; font-weight:bold;">PDRN</td>
<td style="padding:10px; text-align:center;">0.01%</td>
<td style="padding:10px;">Salmon DNA fragments activate A2A adenosine receptors on fibroblasts. Triggers collagen and elastin synthesis. Supports tissue repair.</td>
<td style="padding:10px;">Week 2–4</td>
</tr>
<tr>
<td style="padding:10px; font-weight:bold;">Exosomes</td>
<td style="padding:10px; text-align:center;">High-concentration</td>
<td style="padding:10px;">Nanosized vesicles carrying growth factors, miRNAs and signalling proteins. Reprogram local cells for regeneration, collagen production and inflammation reduction.</td>
<td style="padding:10px;">Week 2–6 (cumulative)</td>
</tr>
</table>
</div>

<p><strong>The layered timeline is the key selling point for patients:</strong> HA delivers instant gratification (visible glow from Day 1), PDRN delivers medium-term improvement (collagen building from Week 2), and exosomes deliver deep regeneration (cellular reprogramming from Week 2–6). The patient sees continuous improvement over the treatment course rather than a single-moment peak.</p>

<h2 id="vs-asce">Hyalmass vs ASCE+ SRLV: Two Exosome Approaches</h2>

<div style="overflow-x:auto;">
<table style="width:100%; border-collapse:collapse; min-width:500px;">
<tr style="background:#1a237e; color:white;">
<th style="padding:12px; text-align:left;">Feature</th>
<th style="padding:12px; text-align:center;">Hyalmass Aqua Exosome</th>
<th style="padding:12px; text-align:center;">ASCE+ SRLV</th>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Manufacturer</td>
<td style="padding:10px; text-align:center;">Maypharm / Beauty Factory</td>
<td style="padding:10px; text-align:center;">ExoCoBio</td>
</tr>
<tr style="border-bottom:1px solid #eee; background:#f8f9fa;">
<td style="padding:10px;">Format</td>
<td style="padding:10px; text-align:center; font-weight:bold; color:#2e7d32;">Pre-mixed syringe (no prep)</td>
<td style="padding:10px; text-align:center;">2-vial kit (reconstitute before use)</td>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Exosome delivery</td>
<td style="padding:10px; text-align:center;">Pre-blended with HA + PDRN in liquid form</td>
<td style="padding:10px; text-align:center;">Lyophilized powder — reconstitute before use</td>
</tr>
<tr style="border-bottom:1px solid #eee; background:#f8f9fa;">
<td style="padding:10px;">Additional actives</td>
<td style="padding:10px; text-align:center; font-weight:bold;">HA + PDRN (triple-active)</td>
<td style="padding:10px; text-align:center;">HA + 10 GFs + 6 peptides + NAD+ + DMAE + glutathione</td>
</tr>
<tr style="border-bottom:1px solid #eee;">
<td style="padding:10px;">Pack size</td>
<td style="padding:10px; text-align:center;">10 × 2.5 mL (25 mL total)</td>
<td style="padding:10px; text-align:center;">20 mg powder + 5 mL activator</td>
</tr>
<tr style="border-bottom:1px solid #eee; background:#f8f9fa;">
<td style="padding:10px;">Best for</td>
<td style="padding:10px; text-align:center;">High-volume clinics wanting simplicity + multi-action</td>
<td style="padding:10px; text-align:center;">Post-device treatment (microneedling/laser add-on)</td>
</tr>
<tr>
<td style="padding:10px;">Positioning</td>
<td style="padding:10px; text-align:center;">"All-in-one convenience"</td>
<td style="padding:10px; text-align:center;">"Maximum exosome potency"</td>
</tr>
</table>
</div>

<p><strong>They serve different clinic models.</strong> Hyalmass is the all-in-one solution — one syringe, no prep, triple mechanism. ASCE+ SRLV is the dedicated exosome platform with a broader ingredient cocktail (10 growth factors, 6 peptides, NAD+, DMAE, glutathione), designed as a post-device add-on. Many clinics stock both: Hyalmass for standalone mesotherapy sessions and ASCE+ for post-microneedling or post-laser enhancement. <a href="/product/asce-plus-srlv/">Compare ASCE+ SRLV →</a></p>

<h2 id="protocol">Treatment Protocol</h2>

<p><strong>Mesotherapy (injection):</strong> 3 sessions at 3–5 week intervals. Use with meso gun, meso jet or manual injection technique. One syringe (2.5 mL) per session for full-face treatment.</p>

<p><strong>Microneedling:</strong> Apply as glide medium during microneedling (0.5–1 mm depth). 1 syringe per session at 3-week intervals. The micro-channels enhance absorption of all three actives.</p>

<p><strong>Topical:</strong> For at-home maintenance between clinic sessions — 1 mL morning and 1 mL evening. This extends the treatment benefit between professional sessions.</p>

<p><strong>Treatment areas:</strong> All facial areas except around the eyes. Neck, décolletage and hands also respond well.</p>

<h2 id="clinic">Why Clinics Are Switching to Triple-Active Boosters</h2>

<p><strong>Operational efficiency.</strong> One product instead of three. No reconstitution. No mixing. One syringe, open and use. For a clinic treating 10 skin booster patients per day, the time savings compound significantly.</p>

<p><strong>Simplified inventory.</strong> Instead of stocking HA boosters, PDRN products and exosome kits separately, Hyalmass covers all three in a single SKU. The 10-syringe box format provides enough product for 3+ complete patient courses.</p>

<p><strong>Premium positioning with justification.</strong> "This treatment combines three active technologies — hyaluronic acid for instant hydration, salmon DNA PDRN for collagen stimulation, and high-concentration exosomes for cellular regeneration" — that's a compelling treatment description that justifies premium per-session pricing.</p>

<p><strong>Competitive wholesale pricing.</strong> At the per-mL cost of Hyalmass, the combined HA + PDRN + exosome value significantly undercuts what it would cost to stock three separate products. <a href="/product/hyalmass-aqua-exosome/">Check Hyalmass wholesale pricing →</a></p>

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<h3 style="margin-top:0; color:#2e7d32;">Practitioner Confidence Summary</h3>
<p>Hyalmass Aqua Exosome simplifies regenerative skin treatment: three actives, one syringe, no prep. The HA delivers instant patient satisfaction, the PDRN builds collagen over weeks, and the exosomes reprogram cellular behaviour for lasting improvement. The pre-mixed, 10-syringe format is designed for high-volume clinic efficiency. For practices looking to offer exosome-level treatment without the complexity of 2-vial reconstitution kits, Hyalmass delivers multi-mechanism results in the simplest possible workflow. <a href="/product/hyalmass-aqua-exosome/">View Hyalmass product details →</a></p>
</div>

<h2 id="faq">Frequently Asked Questions</h2>

<h3>What is Hyalmass Aqua Exosome?</h3>
<p>A triple-active skin booster combining 1% hyaluronic acid, 0.01% salmon-DNA PDRN and billions of exosome particles per 2.5 mL pre-mixed syringe. Manufactured by Maypharm (South Korea). Comes in a 10-syringe box. No reconstitution needed.</p>

<h3>How does Hyalmass compare to ASCE+ SRLV?</h3>
<p>Different approaches. Hyalmass is an all-in-one pre-mixed syringe (HA + PDRN + exosomes) for standalone mesotherapy. ASCE+ SRLV is a 2-vial reconstitution kit with a broader ingredient cocktail designed as a post-device add-on. Many clinics stock both for different use cases.</p>

<h3>How many Hyalmass sessions do I need?</h3>
<p>For mesotherapy: 3 sessions at 3–5 week intervals. For microneedling: 1 syringe per session at 3-week intervals. Results are visible from the first session (HA hydration) with cumulative improvement over the full course (PDRN collagen + exosome regeneration).</p>

<h3>Does Hyalmass require reconstitution?</h3>
<p>No. Hyalmass is pre-mixed and ready to use. Open the syringe and apply. This is a key differentiator from 2-vial exosome kits that require lyophilized powder reconstitution before each treatment.</p>

<h3>What areas can be treated with Hyalmass?</h3>
<p>All facial areas except around the eyes. Also suitable for neck, décolletage and hands. Can be applied via mesotherapy injection, microneedling, meso gun, meso jet or topically for at-home maintenance.</p>

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<h3 style="margin-top:0;">Related Guides</h3>
<ul>
<li><a href="/exosome-therapy-aesthetics-guide/">Exosome Therapy in Aesthetics: Complete Guide</a></li>
<li><a href="/product/asce-plus-srlv/">ASCE+ SRLV Exosome Kit</a></li>
<li><a href="/product/hyalmass-aqua-exosome/">Hyalmass Product Details</a></li>
<li><a href="/">Browse All Products →</a></li>
</ul>
</div>

<p style="font-size:12px; color:#999; margin-top:40px;">Disclosure: FillersFairy is a wholesale supplier of Hyalmass and other aesthetic products. This article is for educational purposes only and does not constitute medical advice.</p>

<h2 style="font-size:18px; color:#555; margin-top:20px;">References</h2>
<ol style="font-size:14px; color:#666; line-height:2;">
<li>Maypharm Co., Ltd. Hyalmass Aqua Exosome product specifications and global launch documentation. December 2024.</li>
<li>Personal Care Insights. "Maypharm launches Hyalmass Aqua-Exosome: A hybrid filler combining hydration and regeneration." January 2025.</li>
<li>TradeKorea. Hyalmass Aqua Exosome product listing. tradekorea.com.</li>
</ol>