Country of origin · Republic of Korea
AestheFill® is a Korean MFDS-approved PDLLA collagen biostimulator — 200 mg of porous poly-D,L-lactic acid microspheres (20–50 µm) in a CMC carrier, supplied as a lyophilized powder for reconstitution. It stimulates your own collagen for gradual, natural rejuvenation rather than acting as an instant filler.
Why choose AestheFill
How AestheFill stimulates collagen
After injection, the PDLLA microspheres act as a temporary scaffold that prompts fibroblasts to lay down new collagen. The spheres resorb over roughly 1.5–2 years while the collagen they induce keeps supporting the tissue — an initial effect plus longer-term remodelling.
AestheFill specifications
AestheFill treatment areas
The areas below are commonly treated with this category of product by practitioners. Suitability, technique, and dosing for any given area are determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Contraindications
AestheFill — frequently asked questions
AestheFill® is a Korean collagen biostimulator based on poly-D,L-lactic acid (PDLLA). Each vial contains 200 mg of porous PDLLA microspheres in a carboxymethylcellulose carrier, supplied as a lyophilized powder that is reconstituted before injection.
Its PDLLA microspheres act as a temporary scaffold that prompts fibroblasts to produce new collagen. The spheres are gradually resorbed while the collagen they induce continues to support the tissue, so results build over weeks to months.
AestheFill is approved by the Korean MFDS; it is not a US FDA-approved product. PDLLA as a raw material is recognised for biocompatibility, but that is separate from the finished product’s regulatory status. Verify the product’s status in your jurisdiction before use.
The collagen stimulated by AestheFill can support results for up to around two years, depending on the area treated and individual factors. Duration varies by patient.
Both are polylactic-acid biostimulators. Sculptra uses PLLA and is FDA-approved in the United States; AestheFill uses PDLLA porous microspheres and is Korean MFDS-approved. Particle structure and regulatory status differ between the two.
Yes. AestheFill is supplied as a lyophilized powder and reconstituted with sterile water before injection. The specific preparation is determined by the treating physician according to their technique.
Store at room temperature, away from direct sunlight, and do not freeze. Refer to the packaging for the printed expiry date.
AestheFill is a professional injectable intended for licensed healthcare professionals trained in PDLLA-based collagen stimulators, used in accordance with local regulations and the official instructions for use.
Silas Vance –
For anyone looking to fix neck lines and skin laxity, I highly recommend this. I tried one vial on my own neck, and the results lasted way longer than standard mesotherapy. It doesn’t just fill lines; it makes the skin thicker and tighter. There’s some mild swelling for a few days, but once it settles, the skin texture is next level. Compared to Ellanse, it’s less likely to migrate and feels safer.
Rachel ThompsonRachel Thompson –
I was terrified of granulomas, which is why I avoided biostimulators for a long time. My research showed Aesthefill’s PDLLA is way more biocompatible. I’m on month 12 now and my temple hollows are perfectly filled. You do have to remember to massage your face for a few days after the procedure, which is slightly annoying, but the results are so gradual and natural that nobody knows I had work done. They just tell me I look rested.