INI Bio Co., Ltd. (GC Wellbeing subsidiary) · Republic of Korea
INIBO 100U by INI Bio Co., Ltd. is a vacuum-dried botulinum toxin type A. Each single-use vial contains 100 units of Clostridium botulinum from INI Bio’s proprietary production line. INI Bio is a subsidiary of GC Wellbeing within the Green Cross (GC) Group — one of the larger Korean pharmaceutical groups. The 100-unit single-vial format is the most common pack size for individual aesthetic sessions.
This product is vacuum-dried. The vial may appear nearly empty before reconstitution — this is normal product appearance, not a defect. The full dose is present and dissolves into a clear, colourless solution when reconstituted with sterile saline.
Why this product is different
INIBO is manufactured by INI Bio Co., Ltd., a subsidiary of GC Wellbeing under the Green Cross (GC) Group. The GC Group is one of the larger Korean pharmaceutical groups, with established manufacturing infrastructure and quality systems. INIBO is INI Bio’s botulinum toxin type A brand, produced using vacuum-drying with INI Bio’s proprietary working strain of Clostridium botulinum. The vacuum-drying manufacturing process produces a thinner, less-visible product layer in the vial than freeze-drying — the vial may appear nearly empty, which is normal product appearance.
Mechanism of action
Botulinum toxin type A is a presynaptic neuromuscular blocker. Following injection into target muscle, the toxin’s heavy chain binds to specific receptors on motor nerve terminals; the light chain is internalised into the nerve cytoplasm, where it enzymatically cleaves SNAP-25 — a SNARE complex protein required for acetylcholine vesicle fusion at the neuromuscular junction. Without SNAP-25, acetylcholine release into the synaptic cleft is blocked, the motor nerve cannot signal the muscle fibre to contract, and the targeted muscle relaxes. New axon terminals eventually sprout and restore neuromuscular signalling, at which point clinical effect wanes.
Specifications
Common application zones
Application zones below are common indications for which botulinum toxin type A is used by practitioners. Specific dosing per zone is determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Contraindications
Frequently asked questions
INIBO 100U is a vacuum-dried Korean botulinum toxin type A manufactured by INI Bio Co., Ltd. Each single-use vial contains 100 units of botulinum toxin type A, reconstituted with 0.9% sterile saline before injection.
INIBO is manufactured by INI Bio Co., Ltd., a subsidiary of GC Wellbeing within the Green Cross (GC) Group in the Republic of Korea. The GC Group is one of the larger Korean pharmaceutical groups.
INIBO uses vacuum-drying as the manufacturing process. Vacuum-drying produces a much thinner product layer than freeze-drying — the vial may appear nearly empty or have only a faint dried film. This is normal product appearance, not a defect. The full 100 units of botulinum toxin type A are present.
Yes. INI Bio Co., Ltd. is a subsidiary of GC Wellbeing within the Green Cross (GC) Group. The GC Group is one of the larger Korean pharmaceutical and biopharmaceutical groups.
Common aesthetic application zones include glabellar lines, forehead lines, lateral canthal lines, masseter contouring, brow lift refinement, mentalis muscle, and platysma bands. Specific dosing per zone is determined by the treating practitioner.
INIBO 100U is the single-vial single-patient pack. INIBO 200U is a higher-unit-count vial for multi-patient sessions or larger treatment areas. Both share the same INI Bio proprietary working strain and vacuum-drying process.
Both are Korean botulinum toxin type A products from different manufacturers using different manufacturing processes. INIBO is manufactured by INI Bio (GC Wellbeing subsidiary) using vacuum-drying. Botulax is manufactured by Hugel Pharma using freeze-drying with Hugel’s proprietary working strain.
Both are vacuum-dried Korean botulinum toxin type A products from different manufacturers. INIBO is manufactured by INI Bio (GC Group). Nabota is manufactured by Daewoong Pharmaceutical.
Onset and duration vary with individual anatomy, muscle mass, metabolism, treatment zone, and dosing strategy.
Store unopened vials at 2–8 °C, protected from light. Do not freeze. After reconstitution with 0.9% sterile saline, use within 24 hours when stored refrigerated.
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