Why this product is different
Toxta is manufactured by JETEMA Co., Ltd., a KOSDAQ-listed Korean biopharmaceutical company. JETEMA operates its own botulinum toxin production line and maintains a proprietary working strain of Clostridium botulinum in its production seed bank. The vacuum-drying manufacturing process produces a thinner, less-visible product layer in the vial than freeze-drying — the vial may appear nearly empty, which is normal product appearance, not a defect. JETEMA also markets Kaimax (sister brand from the same production platform). Toxta and Kaimax are both vacuum-dried JETEMA products with the same proprietary strain.
Mechanism of action
Botulinum toxin type A is a presynaptic neuromuscular blocker. Following injection into target muscle, the toxin’s heavy chain binds to specific receptors on motor nerve terminals; the light chain is internalised into the nerve cytoplasm, where it enzymatically cleaves SNAP-25 — a SNARE complex protein required for acetylcholine vesicle fusion at the neuromuscular junction. Without SNAP-25, acetylcholine release into the synaptic cleft is blocked, the motor nerve cannot signal the muscle fibre to contract, and the targeted muscle relaxes. New axon terminals eventually sprout and restore neuromuscular signalling, at which point clinical effect wanes.
Specifications
Category
Botulinum Toxin Type A — Vacuum-dried
Manufacturer
JETEMA Co., Ltd.
Country of origin
Republic of Korea
Strain
Clostridium botulinum proprietary working strain (JETEMA production seed bank, strain identity not publicly disclosed)
Process
Vacuum-drying
Active ingredients
Botulinum toxin type A 100 U; human serum albumin (stabilizer); sodium chloride
Pack
1 vial × 100 U vacuum-dried powder
Storage (unopened)
2–8 °C, protected from light. Do not freeze.
Shelf life
36 months from date of manufacture (unopened, refrigerated)
After reconstitution
Use within 24 hours when stored at 2–8 °C; discard unused reconstituted product per institutional protocol
Supplied to
Licensed healthcare professionals only
Shipping
Cold-chain (2–8 °C), insulated packaging
SKU
FF-TX-TOXTA-100U
Common application zones
Application zones below are common indications for which botulinum toxin type A is used by practitioners. Specific dosing per zone is determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Multi-zone single-patient sessions (multiple facial areas treated in one visit)
Bilateral masseter contouring with adjunct facial zones
Calf slimming and other body-contouring indications
Platysma bands across the full neck
Hyperhidrosis (axillary, palmar) as a therapeutic indication
Glabellar lines, forehead lines, lateral canthal lines (crow’s feet)
Contraindications
Pregnancy and lactation
Active infection at injection site
Known hypersensitivity to botulinum toxin, human albumin, or any excipient
Neuromuscular disorders (myasthenia gravis, Lambert-Eaton, ALS)
Concurrent aminoglycosides or other neuromuscular blockers
Bleeding disorders or anticoagulants without clearance
Frequently asked questions
What is Toxta 100U?
Toxta 100U is a vacuum-dried Korean botulinum toxin type A manufactured by JETEMA Co., Ltd. Each single-use vial contains 100 units of botulinum toxin type A, reconstituted with 0.9% sterile saline before injection. Vacuum-dried products typically show very thin or barely-visible product layer in the vial — this is normal.
Who manufactures Toxta?
Toxta is manufactured by JETEMA Co., Ltd., a KOSDAQ-listed Korean biopharmaceutical company. JETEMA operates its own dedicated botulinum toxin production line and uses a proprietary working strain of Clostridium botulinum.
Why does the Toxta vial look empty?
Toxta uses vacuum-drying as the manufacturing process. Vacuum-drying produces a much thinner product layer than freeze-drying — the vial may appear nearly empty or have only a faint dried film, which is normal and not a defect. The full 100 units of botulinum toxin type A are present and dissolve when reconstituted with 0.9% sterile saline.
How is Toxta different from Kaimax?
Both Toxta and Kaimax are manufactured by JETEMA Co., Ltd. using the same production platform and same proprietary working strain. They are sister products targeting different brand positioning in different markets. The active ingredient, vacuum-drying process, and excipient profile are equivalent.
What is Toxta commonly used for?
Common aesthetic application zones include glabellar lines, forehead lines, lateral canthal lines (crow’s feet), masseter contouring, brow lift refinement, mentalis muscle, and platysma bands. Therapeutic uses include hyperhidrosis. Specific dosing per zone is determined by the treating practitioner.
How is Toxta 100U different from Toxta 200U?
Toxta 100U is the single-vial single-patient pack — the most common format for individual aesthetic sessions. Toxta 200U is a higher-unit-count vial suited for multi-patient sessions or larger treatment areas in a single patient. Both share the same JETEMA proprietary working strain and vacuum-drying process.
How is Toxta different from Botulax?
Both are Korean botulinum toxin type A products from different manufacturers using different working strains and different manufacturing processes. Toxta is manufactured by JETEMA using vacuum-drying. Botulax is manufactured by Hugel Pharma using freeze-drying with Hugel’s proprietary working strain. Choice depends on practitioner preference.
How is Toxta different from Nabota?
Both are vacuum-dried Korean botulinum toxin type A products from different manufacturers. Toxta is manufactured by JETEMA. Nabota is manufactured by Daewoong Pharmaceutical using Daewoong’s wild-type Clostridium botulinum strain. Both are vacuum-dried so the vial may appear nearly empty before reconstitution — this is normal for both products.
How long does Toxta last?
Onset and duration vary with individual anatomy, muscle mass, metabolism, treatment zone, and dosing strategy. Practitioners can refer to published clinical literature for general expectations specific to their indication.
What are the storage requirements?
Store unopened vials at 2–8 °C, protected from light. Do not freeze. After reconstitution with 0.9% sterile saline, the solution is typically used within 24 hours when stored refrigerated. Discard any unused reconstituted product per institutional protocol.
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