Rejeunesse Shape — UPHEC HA Filler for Facial Contouring & Lip Augmentation
Rejeunesse Shape is Newmedic’s mid-density variant — 24 mg/mL cross-linked HA + 0.3% lidocaine via patented UPHEC technology and high cross-linking density. Engineered for mid-to-deep dermal placement targeting facial contouring (lips, cheeks, jawlines), nasolabial folds, and moderate-to-deep wrinkles. Up to 12 months durability per Newmedic clinical data.
Manufacturer: Newmedic Co. Ltd., South Korea · Established 2014
How Rejeunesse Shape with Lidocaine Is Engineered
UPHEC (Ultra-Purified High-Efficiency Cross-linking) Technology
Newmedic Co. Ltd.’s proprietary cross-linking process produces a stabilised HA gel matrix engineered for sustained tissue retention. The technology balances viscoelasticity (firmness for projection) with extrusion smoothness (easier injection through the 27G needle). The result: predictable handling, consistent gel distribution, and Up to 12 months durability in mid to deep dermis placement.
Quality & Purity
Non-animal hyaluronic acid produced by bacterial fermentation. Endotoxin levels controlled below international safety thresholds. Stringent manufacturing under GMP-certified conditions minimises BDDE residue, heavy metals, and protein contaminants — reducing the risk of post-injection inflammation, granuloma formation, or hypersensitivity reactions in suitable patient profiles.
Rejeunesse Shape with Lidocaine Active Ingredients
Cross-Linked Hyaluronic Acid
Non-animal hyaluronic acid produced by bacterial fermentation, cross-linked using Newmedic Co. Ltd.’s UPHEC (Ultra-Purified High-Efficiency Cross-linking) Technology technology. The cross-linking process creates a stable, durable gel matrix that resists rapid enzymatic breakdown in tissue. Phosphate-buffered saline carries the gel at near-physiological pH.
Lidocaine HCl
Premixed local anaesthetic at the industry-standard 0.3% concentration. Reduces injection-site discomfort and eliminates the need for on-site mixing with separate lidocaine vials. The lidocaine itself wears off within hours of injection and does not affect long-term gel duration.
Where Rejeunesse Shape with Lidocaine Is Used
Nasolabial Folds
Primary indication. Moderate-to-pronounced nose-to-mouth folds.
Lip Augmentation
Lip body volumising via mid-dermal placement. The cohesive UPHEC gel supports sustained shape retention.
Cheek Volumising
Midface enhancement via deep dermal placement.
Jawline Refinement
Mandibular angle definition and subtle jaw contouring.
Rejeunesse Shape with Lidocaine vs Juvederm vs Restylane
| Feature | Rejeunesse | Juvederm (Allergan) | Restylane (Galderma) |
|---|---|---|---|
| HA Concentration | 24 mg/mL | 15–24 mg/mL | 20 mg/mL |
| Cross-Linking Tech | UPHEC | Vycross / Hylacross | NASHA® / OBT |
| Lidocaine | 0.3% (premixed) | 0.3% (XC lines) | 0.3% (Lidocaine variants) |
| Duration | Up to 12 months | 6–24 months (varies) | 6–18 months (varies) |
| Origin | South Korea (Newmedic Co. Ltd.) | USA (Allergan / AbbVie) | Sweden (Galderma) |
| Established Since | 2014 | 2006 | 1996 |
↔ Swipe horizontally on mobile to view all columns
Comparison based on manufacturer published data. See our top dermal filler comparison guide for broader market context.
Rejeunesse Shape with Lidocaine Product Specifications
Manufacturer
- Brand: Rejeunesse
- Company: Newmedic Co. Ltd.
- Country: South Korea
- Established: 2014
Formula
- HA Source: Non-animal bacterial fermentation
- HA Concentration: 24 mg/mL
- Lidocaine: 0.3% (3 mg/mL) premixed
- Cross-linking: UPHEC (Ultra-Purified High-Efficiency Cross-linking) Technology
Performance
- Duration: Up to 12 months
- Injection Depth: Mid to deep dermis
- Recommended Needle: 27G
- Last Reviewed: May 2026
Approval & Storage
- Approvals: KFDA registered · CE marked · GMP certified
- Packaging: 1 x 1.1 mL pre-filled syringe
- Storage: 2–25 °C, do not freeze
- Shelf life: 24 months unopened
Verify regulatory status at the official Korean MFDS database — nedrug.mfds.go.kr. For market pricing context, see our dermal filler pricing guide.
Rejeunesse Shape with Lidocaine — Frequently Asked Questions
What is Rejeunesse Shape with Lidocaine?
Rejeunesse Shape is Newmedic’s mid-density variant — 24 mg/mL cross-linked HA + 0.3% lidocaine via patented UPHEC technology and high cross-linking density. Engineered for mid-to-deep dermal placement targeting facial contouring (lips, cheeks, jawlines), nasolabial folds, and moderate-to-deep wrinkles. Up to 12 months durability per Newmedic clinical data.
Where is Rejeunesse Shape with Lidocaine manufactured?
Rejeunesse Shape with Lidocaine is manufactured by Newmedic Co. Ltd., a South Korea-based medical device and pharmaceutical company established in 2014. The product is part of the Rejeunesse dermal filler range, which is distributed across multiple international markets. Regulatory status: KFDA registered · CE marked · GMP certified.
What is the HA concentration in Rejeunesse Shape with Lidocaine?
Rejeunesse Shape with Lidocaine contains 24 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using Newmedic Co. Ltd.’s UPHEC (Ultra-Purified High-Efficiency Cross-linking) Technology technology. Phosphate-buffered saline at near-physiological pH carries the gel.
How long do Rejeunesse Shape with Lidocaine results last?
Per Newmedic Co. Ltd.’s clinical data, Rejeunesse Shape with Lidocaine delivers Up to 12 months of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Mid to deep dermis placement typically delivers the longer end of the duration range.
What is the recommended injection depth for Rejeunesse Shape with Lidocaine?
Rejeunesse Shape with Lidocaine is engineered for mid to deep dermis placement. The standard recommended needle is 27G, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.
Is Rejeunesse Shape with Lidocaine FDA approved or CE marked?
Rejeunesse Shape with Lidocaine regulatory status: KFDA registered · CE marked · GMP certified. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.
How should Rejeunesse Shape with Lidocaine be stored at the clinic?
Store Rejeunesse Shape with Lidocaine between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.
Does Rejeunesse Shape with Lidocaine contain animal-derived ingredients?
No. Rejeunesse Shape with Lidocaine uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).
Can Rejeunesse Shape with Lidocaine be combined with other dermal fillers in the same session?
Yes — layered protocols combining different fillers are standard aesthetic practice. Rejeunesse Shape with Lidocaine can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.
Why does Rejeunesse Shape have a 9% cross-linking rate?
Newmedic intentionally designed the Rejeunesse range with a low (approximately 9%) cross-linking rate compared to many high-density Korean fillers. The lower cross-linking gives the gel exceptional softness, elasticity, and pliability — supporting the ability to fill hard-to-reach dermal cavities while integrating naturally with surrounding tissue. UPHEC’s ultra-purification compensates for the lower cross-linking density to maintain sustained durability through enzyme resistance rather than dense structural cross-links. Net result: softer feel post-injection with comparable longevity.
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Browse category →Read Before Clinical Use
Rejeunesse Shape with Lidocaine is a prescription medical device for use only by licensed aesthetic practitioners. Common reactions include injection-site bruising, swelling, redness, and tenderness — generally resolving within days. Like all hyaluronic acid dermal fillers, treatment carries rare but serious vascular complication risks. Contraindicated in patients with known hypersensitivity to hyaluronic acid or lidocaine, active skin infection at the treatment site, pregnancy, or breastfeeding. Full contraindications, vascular complication protocols, aftercare, and emergency guidance are detailed on the dermal filler safety page.
Read Full Dermal Filler Safety Information →Rejeunesse is a registered trademark of Newmedic Co. Ltd.. Fillersfairy.com is a channel distributor and does not provide medical advice. This page is for informational purposes only and does not replace the manufacturer’s official Instructions for Use, which remains the authoritative source for clinical administration. Regulatory status varies by jurisdiction — buyers are responsible for verifying legal status before ordering. Last reviewed May 2026 against Newmedic Co. Ltd. manufacturer documentation.

Olivia Green –
Injecting it was a dream, thanks to the fine needles and lidocaine blend. My clients reported less pain right away, and the volume boost looks amazing for months.
Emily Carter –
I ordered 20 units of Rejeunesse Shape to get that 8% bulk discount – saved a ton compared to other sites. The delivery was lightning-fast, got it in under a week with perfect cold packaging, and the real-time tracking made it easy to plan my appointments right. Honestly, after checking out competitors, fillersfairy’s deals and authenticity sealed it.