Sosum S — LTSR HA Filler for Fine Lines (Lidocaine-Free, 2 x 1ml)
Sosum S is JSBIO’s lightest variant — 20 mg/mL cross-linked HA produced via patented LTSR (Low-Temperature Stabilization Reaction) technology with zero residual BDDE. Lidocaine-free formulation for practitioners managing separate anaesthesia. Engineered for superficial dermal placement targeting fine lines, forehead, and neck wrinkles. 2 x 1 mL pack with JBP nanoneedles included.
Manufacturer: JSBIO Co. Ltd., South Korea · Established 2013
How Sosum S Fine Lines Dermal Filler Is Engineered
Low-Temperature Stabilization Reaction Technology
JSBIO Co. Ltd.’s proprietary cross-linking process produces a stabilised HA gel matrix engineered for sustained tissue retention. The technology balances viscoelasticity (firmness for projection) with extrusion smoothness (easier injection through the 30G + JBP nanoneedles needle). The result: predictable handling, consistent gel distribution, and Up to 12 months durability in superficial dermis placement.
Quality & Purity
Non-animal hyaluronic acid produced by bacterial fermentation. Endotoxin levels controlled below international safety thresholds. Stringent manufacturing under GMP-certified conditions minimises BDDE residue, heavy metals, and protein contaminants — reducing the risk of post-injection inflammation, granuloma formation, or hypersensitivity reactions in suitable patient profiles.
Sosum S Fine Lines Dermal Filler Active Ingredients
Cross-Linked Hyaluronic Acid
Non-animal hyaluronic acid produced by bacterial fermentation, cross-linked using JSBIO Co. Ltd.’s Low-Temperature Stabilization Reaction Technology technology. The cross-linking process creates a stable, durable gel matrix that resists rapid enzymatic breakdown in tissue. Phosphate-buffered saline carries the gel at near-physiological pH.
Lidocaine HCl
Premixed local anaesthetic at the industry-standard 0.3% concentration. Reduces injection-site discomfort and eliminates the need for on-site mixing with separate lidocaine vials. The lidocaine itself wears off within hours of injection and does not affect long-term gel duration.
Where Sosum S Fine Lines Dermal Filler Is Used
Fine Forehead Lines
Primary indication. Superficial horizontal forehead wrinkles. The 30G needle and superficial placement protocol suit this zone.
Periorbital Crow’s Feet
Fine lines around the eyes. The lidocaine-free formulation supports practitioners managing separate periorbital anaesthesia.
Glabellar Lines
Vertical glabella creases. Superficial dermal placement standard.
Neck Lines & Décolleté
Off-face indications — neck horizontal lines and décolleté chest wrinkles. Less common but supported by the Sosum range.
Sosum S Fine Lines Dermal Filler vs Juvederm vs Restylane
| Feature | Sosum | Juvederm (Allergan) | Restylane (Galderma) |
|---|---|---|---|
| HA Concentration | 20 mg/mL | 15–24 mg/mL | 20 mg/mL |
| Cross-Linking Tech | LTSR | Vycross / Hylacross | NASHA® / OBT |
| Lidocaine | 0.3% (premixed) | 0.3% (XC lines) | 0.3% (Lidocaine variants) |
| Duration | Up to 12 months | 6–24 months (varies) | 6–18 months (varies) |
| Origin | South Korea (JSBIO Co. Ltd.) | USA (Allergan / AbbVie) | Sweden (Galderma) |
| Established Since | 2013 | 2006 | 1996 |
↔ Swipe horizontally on mobile to view all columns
Comparison based on manufacturer published data. See our top dermal filler comparison guide for broader market context.
Sosum S Fine Lines Dermal Filler Product Specifications
Manufacturer
- Brand: Sosum
- Company: JSBIO Co. Ltd.
- Country: South Korea
- Established: 2013
Formula
- HA Source: Non-animal bacterial fermentation
- HA Concentration: 20 mg/mL
- Lidocaine: 0.3% (3 mg/mL) premixed
- Cross-linking: Low-Temperature Stabilization Reaction Technology
Performance
- Duration: Up to 12 months
- Injection Depth: Superficial dermis
- Recommended Needle: 30G + JBP nanoneedles
- Last Reviewed: May 2026
Approval & Storage
- Approvals: MFDS approval 2013 · CE certified · GMP
- Packaging: 2 x 1 mL syringes + JBP nanoneedles
- Storage: 2–25 °C, do not freeze
- Shelf life: 24 months unopened
Verify regulatory status at the official Korean MFDS database — nedrug.mfds.go.kr. For market pricing context, see our dermal filler pricing guide.
Sosum S Fine Lines Dermal Filler — Frequently Asked Questions
What is Sosum S Fine Lines Dermal Filler?
Sosum S is JSBIO’s lightest variant — 20 mg/mL cross-linked HA produced via patented LTSR (Low-Temperature Stabilization Reaction) technology with zero residual BDDE. Lidocaine-free formulation for practitioners managing separate anaesthesia. Engineered for superficial dermal placement targeting fine lines, forehead, and neck wrinkles. 2 x 1 mL pack with JBP nanoneedles included.
Where is Sosum S Fine Lines Dermal Filler manufactured?
Sosum S Fine Lines Dermal Filler is manufactured by JSBIO Co. Ltd., a South Korea-based medical device and pharmaceutical company established in 2013. The product is part of the Sosum dermal filler range, which is distributed across multiple international markets. Regulatory status: MFDS approval 2013 · CE certified · GMP.
What is the HA concentration in Sosum S Fine Lines Dermal Filler?
Sosum S Fine Lines Dermal Filler contains 20 mg/mL of cross-linked hyaluronic acid plus 0.3% (3 mg/mL) premixed lidocaine for injection comfort. The hyaluronic acid is non-animal, produced by bacterial fermentation and cross-linked using JSBIO Co. Ltd.’s Low-Temperature Stabilization Reaction Technology technology. Phosphate-buffered saline at near-physiological pH carries the gel.
How long do Sosum S Fine Lines Dermal Filler results last?
Per JSBIO Co. Ltd.’s clinical data, Sosum S Fine Lines Dermal Filler delivers Up to 12 months of correction depending on placement and patient factors. Duration depends on injection depth, dose, anatomical site, patient metabolism, and facial movement intensity. Superficial dermis placement typically delivers the longer end of the duration range.
What is the recommended injection depth for Sosum S Fine Lines Dermal Filler?
Sosum S Fine Lines Dermal Filler is engineered for superficial dermis placement. The standard recommended needle is 30G + JBP nanoneedles, supplied in the syringe blister pack. Some practitioners prefer a blunt-tip cannula of equivalent gauge for safer placement in highly vascular zones, particularly for deeper subcutaneous work.
Is Sosum S Fine Lines Dermal Filler FDA approved or CE marked?
Sosum S Fine Lines Dermal Filler regulatory status: MFDS approval 2013 · CE certified · GMP. The product’s KFDA registration in South Korea is the primary regulatory baseline. CE marking and other international approvals enable distribution in the EU and other regulated markets. US FDA status varies — buyers in regulated jurisdictions should verify approval scope before importation and clinical use.
How should Sosum S Fine Lines Dermal Filler be stored at the clinic?
Store Sosum S Fine Lines Dermal Filler between 2 °C and 25 °C in original packaging, away from direct sunlight. Do not freeze — freezing damages the HA gel structure. Shelf life is typically 24 months from the manufacturing date printed on the box when unopened. Once a syringe is opened, contents must be used immediately. Partial syringes cannot be retained for later use due to sterility risk.
Does Sosum S Fine Lines Dermal Filler contain animal-derived ingredients?
No. Sosum S Fine Lines Dermal Filler uses non-animal hyaluronic acid produced by bacterial fermentation — the standard manufacturing approach for modern HA dermal fillers. The product contains no animal proteins or by-products, making it suitable for patients who avoid animal-derived medical products. The product is contraindicated in patients with severe allergies to gram-positive bacterial proteins (used in HA fermentation).
Can Sosum S Fine Lines Dermal Filler be combined with other dermal fillers in the same session?
Yes — layered protocols combining different fillers are standard aesthetic practice. Sosum S Fine Lines Dermal Filler can be combined with other Korean or international HA fillers, neuromodulators (botulinum toxin), or biostimulators (PLLA, calcium hydroxylapatite) within a single session. Always wait the recommended interval between different injectable products and confirm biocompatibility per each manufacturer’s IFU.
Why is the Sosum range lidocaine-free?
JSBIO supplies the entire Sosum range without integrated lidocaine to serve practitioners who prefer separate anaesthesia control — for example, combining filler placement with topical anaesthesia, nerve blocks, or to support patients with documented lidocaine sensitivity. The lidocaine-free formulation also supports the no-needle (cannula) injection technique that some practitioners use with Sosum. Each box includes JBP nanoneedles for precise placement. For practitioners requiring premixed lidocaine, alternative Korean HA fillers like Bellast or Bonetta include 0.3% lidocaine.
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Browse category →Read Before Clinical Use
Sosum S Fine Lines Dermal Filler is a prescription medical device for use only by licensed aesthetic practitioners. Common reactions include injection-site bruising, swelling, redness, and tenderness — generally resolving within days. Like all hyaluronic acid dermal fillers, treatment carries rare but serious vascular complication risks. Contraindicated in patients with known hypersensitivity to hyaluronic acid or lidocaine, active skin infection at the treatment site, pregnancy, or breastfeeding. Full contraindications, vascular complication protocols, aftercare, and emergency guidance are detailed on the dermal filler safety page.
Read Full Dermal Filler Safety Information →Sosum is a registered trademark of JSBIO Co. Ltd.. Fillersfairy.com is a channel distributor and does not provide medical advice. This page is for informational purposes only and does not replace the manufacturer’s official Instructions for Use, which remains the authoritative source for clinical administration. Regulatory status varies by jurisdiction — buyers are responsible for verifying legal status before ordering. Last reviewed May 2026 against JSBIO Co. Ltd. manufacturer documentation.


Liam Torres –
Third time buying Sosum S this stuff’s magic for crow’s feet! Fillersfairy’s discount on bulk orders saved me a ton. The texture glides smoothly, and it blends like my own skin.
Ben Carter –
Just got my Sosum S filler from fillersfairy last week super fast shipping the payment process was smooth. Used it on my smile lines yesterday, and wow! Super fine needles made it almost painless. Skin looks plump and natural, no weird puffiness.