Country of origin · Republic of Korea
AMI Plus X is a Korean high-dose polynucleotide skin booster — 2% PN at 20 mg/ml, 40 mg total in a ready-to-use 2 ml syringe. The salmon-DNA-derived PN activates fibroblasts to build new collagen and elastin, improving skin density, firmness and texture across the face, neck and hands.
Why choose AMI Plus X
How AMI Plus X works
Polynucleotides are purified salmon-DNA fragments that act on fibroblasts and provide a scaffold within the dermis, prompting new collagen and elastin production. At 2% (20 mg/ml), AMI Plus X delivers double the PN concentration of the 1% eye formulation — results build progressively over a treatment course.
AMI Plus X specifications
AMI Plus X treatment areas
- ·Full face — skin density and firmness
- ·Neck and décolleté
- ·Back of the hands
- ·Skin texture, pores and fine lines
- ·Skin elasticity and hydration
Contraindications
- ·Pregnancy and lactation
- ·Active infection, inflammation, or skin lesions at or near the treatment area
- ·Known hypersensitivity to any component of the product, including fish-derived materials
- ·History of keloid or hypertrophic scarring
- ·Bleeding disorders or anticoagulant therapy without appropriate clearance
AMI Plus X — frequently asked questions
AMI Plus X is a Korean polynucleotide (PN) skin booster containing 2% PN at 20 mg/ml — 40 mg in a ready-to-use 2 ml syringe. The PN is derived from purified salmon DNA and works by stimulating the skin’s own collagen and elastin production.
AMI Plus X carries double the PN concentration of the 1% eye formulation in the same 2 ml volume. The higher dose is intended for larger surface areas and for skin needing more intensive regeneration, rather than the delicate periorbital area.
No. It is a biostimulator: it works by prompting your own fibroblasts to produce collagen and elastin, rather than adding volume the way a hyaluronic acid filler does. It is not reversible with hyaluronidase.
Both come from salmon DNA. PN refers to longer purified polynucleotide chains that also act as a structural scaffold in the dermis; PDRN refers to shorter fragments. Products differ by chain length, purity and concentration.
It is used for the face, neck, décolleté and back of the hands — areas where skin density, elasticity and texture are the treatment goal.
No. It is supplied ready-to-use in a pre-filled syringe. If any dilution or mixing is used, the specific ratio and preparation are determined by the treating physician according to their technique and treatment goal.
Each box carries a HiddenTag® holographic seal that can be scanned with the HiddenTag app to check the encrypted serial number against the official registration record.
Store between 2–25 °C, protected from sunlight and frost. Do not freeze. Refer to the packaging for the printed expiry date.
PN boosters are generally used as a short course of sessions spaced a few weeks apart, with the exact plan set by the treating practitioner based on the individual’s skin. Results build progressively over and after the course.
AMI Plus X is a professional injectable intended for licensed healthcare professionals trained in skin-booster and mesotherapy treatments, used in accordance with local regulations and the official instructions for use.

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