Why this product is different
Botulax 200U gives clinics double the units per vial compared with Botulax 100U, reducing the number of vials needed for larger treatments — bilateral masseter and platysma work, full-face multi-zone sessions, or back-to-back patient sessions where a single reconstituted vial is shared across a same-day appointment window. The reconstitution volume and saline ratio scale accordingly. The active ingredient, strain, and freeze-drying process are identical to Botulax 100U.
Mechanism of action
Botulinum toxin type A blocks acetylcholine release at the neuromuscular junction by cleaving SNAP-25 — a SNARE complex protein essential for vesicle fusion at the motor nerve terminal. The targeted muscle receives no contraction signal and relaxes. Clinical effect wanes as new axon terminals sprout and restore neuromuscular signalling.
Specifications
Category
Botulinum Toxin Type A — Freeze-dried
Manufacturer
Hugel Pharma
Country of origin
Republic of Korea
Strain
Clostridium botulinum strain CBFC26 (Hugel proprietary working strain)
Process
Freeze-drying (lyophilization)
Active ingredients
Clostridium botulinum toxin type A, 200 units per vial. Human serum albumin (stabiliser). Sodium chloride (tonicity adjuster). Hugel CBFC26 working strain.
Pack
1 vial × 200 units. Lyophilized white powder for reconstitution with 0.9% sterile saline before injection.
Storage (unopened)
Store at 2–8 °C, protected from light. Do not freeze.
Shelf life
36 months from manufacturing date (unopened)
After reconstitution
Use within 24 hours when stored at 2–8 °C after reconstitution.
Supplied to
Licensed healthcare professionals only
Shipping
Cold-chain (2–8 °C), insulated packaging
SKU
FF-TX-BOTULAX-200U
Common application zones
Application zones below are common indications for which botulinum toxin type A is used by practitioners. Specific dosing per zone is determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Multi-zone single-patient sessions (multiple facial areas treated in one visit)
Bilateral masseter contouring with adjunct facial zones
Calf slimming and other body-contouring indications
Platysma bands across the full neck
Bilateral axillary hyperhidrosis
Large practice / multi-patient single-session use
Contraindications
Pregnancy and lactation
Active infection at injection site
Known hypersensitivity to botulinum toxin, human albumin, or any excipient
Neuromuscular disorders (myasthenia gravis, Lambert-Eaton, ALS)
Concurrent aminoglycosides or other neuromuscular blockers
Bleeding disorders or anticoagulants without clearance
Frequently asked questions
What is Botulax 200U?
Botulax 200U is the 200-unit single-vial pack of Hugel Pharma’s botulinum toxin type A. The active ingredient, manufacturing process, and CBFC26 strain are identical to Botulax 100U — only the unit count per vial differs.
Who is Botulax 200U for?
Clinicians who regularly run multi-zone single-patient sessions, bilateral body-contouring sessions (masseter, calf, platysma), large practices needing higher-unit vials, and clinics with established same-day shared-vial protocols. The 200U pack reduces vial count and waste for these use cases.
Is Botulax 200U a different formulation from Botulax 100U?
No — same active ingredient, same CBFC26 strain, same freeze-drying process, same excipients (human albumin and sodium chloride). The only difference is total units per vial.
How is the reconstitution different for Botulax 200U?
The saline volume scales with unit-per-volume preference. Manufacturer instructions and institutional protocol specify the standard reconstitution. Reconstitution technique is identical: slow saline injection down the inner vial wall, gentle swirl, inspect for clarity.
Where is Botulax 200U commonly applied?
Multi-zone single-patient sessions covering multiple facial areas in one visit; bilateral body-contouring including masseter and calf; full-neck platysma work; bilateral axillary hyperhidrosis. Higher-unit demand makes the 200U pack efficient for these indications.
How does Botulax 200U compare with Nabota 200U?
Both are Korean botulinum toxin type A in 200-unit packs but from different manufacturers. Botulax 200U (Hugel) uses freeze-drying and the CBFC26 strain. Nabota 200U (Daewoong) uses vacuum-drying and a wild-type strain. Choice depends on practitioner preference and clinical experience.
How long is Botulax 200U stable after reconstitution?
Per manufacturer recommendation, the reconstituted solution is typically used within 24 hours when stored refrigerated at 2–8 °C. Same-day use is best practice for clinical reliability. Discard any remainder after the recommended window.
Is Botulax 200U the same product as Letybo (US)?
Letybo is the US-marketed brand name for Hugel’s botulinum toxin type A. Both products derive from Hugel’s manufacturing platform. However, packaging, labelling, and regulatory status differ. The product on Fillersfairy is the Korean-market Botulax, not the US-labelled Letybo.
Does Botulax 200U require cold-chain shipping?
Yes. Botulinum toxin type A products require continuous cold-chain (2–8 °C) from manufacturer to point of clinical use. Fillersfairy ships botulinum toxin products with cold-chain packaging (insulated containers with refrigerants) to maintain temperature during transit.
What documentation is required to purchase Botulax 200U?
Fillersfairy supplies botulinum toxin products to licensed healthcare professionals only. Verification of professional credentials is required prior to fulfilment. Practitioners are responsible for compliance with their jurisdiction’s regulations on botulinum toxin import, possession, and clinical use.
Ethan Calloway –
I’ve been using Botulax for jaw slimming for a year now, and my face shape has completely changed. Before, my masseters made me look like I was chewing rocks 24/7. My clinic injects 25U per side, and within a week, my jawline got so defined my selfie game leveled up. The muscle atrophy is gradual, and it lasts about 6 months. I also noticed fewer tension headaches—bonus!