Hugel Pharma · Republic of Korea
Botulax 300U by Hugel Pharma is the high-unit-count format in the Botulax product family — 300 units of Clostridium botulinum toxin type A (CBFC26 strain) per single vial as lyophilized white powder. The 300U pack is positioned for high-volume clinics, multi-zone single-patient sessions covering both face and body, and combined aesthetic-plus-therapeutic protocols where total unit demand is high.
Why this product is different
Botulax 300U is the largest single-vial format in the Botulax range — three times the unit count of the standard 100U vial. This reduces per-unit cost for high-volume practices, eliminates the need to use multiple vials in larger treatments, and supports same-day shared-vial protocols where workflow efficiency matters. The active ingredient, CBFC26 strain, freeze-drying process, and excipients are identical to other Botulax pack sizes — only total unit count differs.
Mechanism of action
Botulinum toxin type A blocks acetylcholine release at the neuromuscular junction by cleaving SNAP-25. The targeted muscle receives no contraction signal and relaxes. Clinical effect wanes as new axon terminals sprout.
Specifications
Common application zones
Application zones below are common indications for which botulinum toxin type A is used by practitioners. Specific dosing per zone is determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Contraindications
Frequently asked questions
Botulax 300U is the 300-unit single-vial format of Hugel Pharma’s botulinum toxin type A. The active ingredient, CBFC26 strain, manufacturing process, and excipients are identical to Botulax 100U and 200U — only the unit count differs. The 300U vial is positioned for high-volume clinical use.
High-volume clinics treating multiple patients per session, multi-zone single-patient protocols covering both face and body, combined aesthetic-plus-therapeutic sessions, and practices with established same-day shared-vial workflows. Smaller-volume practices typically use 100U or 200U formats to minimise waste.
Different clinical workflows have different optimal pack sizes. A solo practitioner doing one patient at a time may prefer 100U vials for waste-free single-session use. A busy aesthetics clinic running back-to-back patients in one session may prefer 200U or 300U for cost efficiency and workflow continuity. All three are Hugel’s Botulax with the same CBFC26 strain — choice is operational.
Not inherently. Concentration depends on the reconstitution saline volume the practitioner uses — not the total units per vial. Higher units per vial means more total dose available per vial, not stronger concentration. The practitioner controls concentration by adjusting saline volume per institutional protocol.
High-volume clinics performing multiple patient sessions per single-vial protocol; multi-zone single-patient full-face contouring; bilateral body-contouring covering masseter, calf, deltoid, or trapezius; and combined aesthetic-plus-therapeutic sessions where total unit demand is high in one session.
The saline volume scales with unit-per-volume preference and total target volume across treatment zones. Reconstitution technique is identical: slow saline injection down the inner vial wall, gentle swirl, inspect for clarity. Manufacturer instructions and institutional protocol guide the specific reconstitution parameters.
Unopened: 36 months from manufacturing date at 2–8 °C. After reconstitution: typically used within 24 hours when refrigerated at 2–8 °C, per manufacturer recommendation. Same-day use is best clinical practice. Discard any remainder after the recommended window.
Body-contouring with botulinum toxin (calf slimming, trapezius, deltoid) is a recognised off-label use practised by experienced clinicians. The higher unit count in the 300U vial accommodates larger muscle group treatment without multi-vial reconstitution. Practitioners should follow institutional protocol and informed consent processes for off-label use.
Yes — continuous cold-chain (2–8 °C) from manufacturer to clinic. Fillersfairy ships botulinum toxin products with insulated cold-chain packaging containing refrigerants to maintain temperature during transit.
Yes. Botulinum toxin products on Fillersfairy are supplied exclusively to licensed healthcare professionals. Credential verification is required before fulfilment. Practitioners are responsible for compliance with their jurisdiction’s regulations on import, possession, and clinical use.

Seraphina Thorne –
I’ve been in the aesthetic game for years, switching from Botox to Meditoxin before finally settling on Botulax. Getting the 300ui bulk size was a total game-changer. The 100ui vials were never enough for my trapezius or calf treatments. The purity here is just as stable as the 200ui version I used before, but the value is unbeatable. Unlike some brands that leave you with a “frozen” face, Botulax offers precise diffusion. I did my forehead and masseters; the effect kicked in by day 4, and two months later, everything is still perfectly smooth. If you’re a pro user, the 300ui is a no-brainer.
Dr. Michael T. –
Upgraded to the 300ui vial from the 100ui because I run a busy practice. Reconstitution is smooth and it doesn’t leave residues. Patients are reporting great results for glabellar lines. Compared to Meditoxin, I feel Botulax gives a slightly more “natural” freeze. Will definitely keep ordering from FillersFairy, shipping was surprisingly fast.
Vincent Reed –
Saw ‘temperature-controlled packaging activated’ the minute it shipped, and sure enough, ice packs were still frozen solid when delivered Tuesday. We’ve been using Botulax 300UI on clients for forehead lines. It’s become our go-to. Smoothing starts faster than others we’ve tried (think 3-ish days), and Mrs. Davies came back last week raving about still being crease-free after 5 months. Zero diffusion issues too.