Why this product is different
Hutox is part of the Huons Group’s botulinum toxin product family in Korea. The Huons Group is one of the larger Korean pharmaceutical groups, with botulinum toxin manufacturing capabilities through Huons BioPharma. Each Hutox vial contains 100 units of freeze-dried botulinum toxin type A as a visible white powder cake. Reconstituted with 0.9% sterile saline before injection. Hutox is positioned as a value-priced Korean botulinum toxin type A option within the Huons Group portfolio, suited for clinics seeking a freeze-dried Korean alternative to higher-priced botulinum toxin brands.
Mechanism of action
Botulinum toxin type A is a presynaptic neuromuscular blocker. Following injection into target muscle, the toxin’s heavy chain binds to specific receptors on motor nerve terminals; the light chain is internalised into the nerve cytoplasm, where it enzymatically cleaves SNAP-25 — a SNARE complex protein required for acetylcholine vesicle fusion at the neuromuscular junction. Without SNAP-25, acetylcholine release into the synaptic cleft is blocked, the motor nerve cannot signal the muscle fibre to contract, and the targeted muscle relaxes. New axon terminals eventually sprout and restore neuromuscular signalling, at which point clinical effect wanes.
Specifications
Category
Botulinum Toxin Type A — Freeze-dried
Manufacturer
Huons BioPharma Co., Ltd. (Huons Group)
Country of origin
Republic of Korea
Strain
Clostridium botulinum proprietary working strain (Huons production seed bank)
Process
Freeze-drying (lyophilization)
Active ingredients
Botulinum toxin type A 100 U; human serum albumin (stabilizer); sodium chloride
Pack
1 vial × 100 U lyophilized powder
Storage (unopened)
2–8 °C, protected from light. Do not freeze.
Shelf life
36 months from date of manufacture (unopened, refrigerated)
After reconstitution
Use within 24 hours when stored at 2–8 °C; discard unused reconstituted product per institutional protocol
Supplied to
Licensed healthcare professionals only
Shipping
Cold-chain (2–8 °C), insulated packaging
SKU
FF-TX-HUTOX-100U
Common application zones
Application zones below are common indications for which botulinum toxin type A is used by practitioners. Specific dosing per zone is determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Multi-zone single-patient sessions
Bilateral masseter contouring with adjunct facial zones
Calf slimming and other body-contouring indications
Platysma bands across the full neck
Hyperhidrosis (axillary, palmar) as a therapeutic indication
Glabellar lines, forehead lines, lateral canthal lines (crow’s feet)
Contraindications
Pregnancy and lactation
Active infection at injection site
Known hypersensitivity to botulinum toxin, human albumin, or any excipient
Neuromuscular disorders (myasthenia gravis, Lambert-Eaton, ALS)
Concurrent aminoglycosides or other neuromuscular blockers
Bleeding disorders or anticoagulants without clearance
Frequently asked questions
What is Hutox 100U?
Hutox 100U is a Korean botulinum toxin type A manufactured by Huons BioPharma (Huons Group). Each single-use vial contains 100 units of lyophilized white powder, reconstituted with 0.9% sterile saline before injection.
Who manufactures Hutox?
Hutox is manufactured by Huons BioPharma Co., Ltd., part of the Huons Group in the Republic of Korea. The Huons Group is one of the larger Korean pharmaceutical groups with botulinum toxin manufacturing capability.
How is Hutox related to Liztox?
Both are part of the Huons Group portfolio of botulinum toxin type A products marketed in Korea. Hutox is manufactured by Huons BioPharma; Liztox is manufactured by Humedix Co., Ltd. (also part of the Huons Group). They are sister products under the same parent group but distinct product lines.
Is Hutox freeze-dried or vacuum-dried?
Hutox is freeze-dried (lyophilized). After freeze-drying, a visible white powder cake or thin layer remains in the vial. This is distinct from vacuum-dried botulinum toxins which can appear nearly empty in the vial.
What is Hutox commonly used for?
Common aesthetic application zones include glabellar lines, forehead lines, lateral canthal lines (crow’s feet), masseter contouring, brow lift refinement, mentalis muscle, and platysma bands. Therapeutic uses include hyperhidrosis. Specific dosing per zone is determined by the treating practitioner.
How is Hutox 100U different from Hutox 200U?
Hutox 100U is the single-vial single-patient pack — the most common format for individual aesthetic sessions. Hutox 200U is a higher-unit-count vial for multi-patient sessions or larger treatment areas in a single patient.
How is Hutox different from Botulax?
Both are Korean freeze-dried botulinum toxin type A products from different manufacturers. Hutox is manufactured by Huons BioPharma (Huons Group). Botulax is manufactured by Hugel Pharma using the CBFC26 strain. Choice depends on practitioner preference.
How is Hutox different from Meditoxin?
Both are Korean freeze-dried botulinum toxin type A products from different manufacturers. Hutox is manufactured by Huons BioPharma. Meditoxin is manufactured by Medytox using the Hall A-hyper strain. Choice depends on practitioner preference.
How long does Hutox last?
Onset and duration vary with individual anatomy, muscle mass, metabolism, treatment zone, and dosing strategy. Practitioners can refer to published clinical literature for general expectations.
What are the storage requirements?
Store unopened vials at 2–8 °C, protected from light. Do not freeze. After reconstitution with 0.9% sterile saline, use within 24 hours when stored refrigerated.
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