Pharma Research Bio Co., Ltd. · Republic of Korea
ReNTOX 200U by Pharma Research Bio is the higher-unit-count single-vial format of ReNTOX botulinum toxin type A — 200 units of Clostridium botulinum as lyophilized white powder for reconstitution. Pharma Research Bio is part of the Pharma Research Group (also known for the Rejuran polynucleotide product family). The 200-unit pack is positioned for multi-zone single-patient sessions or multi-patient shared-vial protocols.
Why this product is different
The 200U vial provides twice the unit count of the standard 100U pack in a single vial, supporting multi-zone single-patient treatments or multi-patient sessions when shared-vial protocols are appropriate. ReNTOX 200U is produced from the same Pharma Research Bio proprietary working strain and freeze-drying manufacturing process as ReNTOX 100U. The only difference is unit count per vial. ReNTOX is produced by Pharma Research Bio, a subsidiary of the Pharma Research Group. ReNTOX is the group’s botulinum toxin type A offering.
Mechanism of action
Botulinum toxin type A is a presynaptic neuromuscular blocker. Following injection into target muscle, the toxin’s heavy chain binds to specific receptors on motor nerve terminals; the light chain is internalised into the nerve cytoplasm, where it enzymatically cleaves SNAP-25 — a SNARE complex protein required for acetylcholine vesicle fusion at the neuromuscular junction. Without SNAP-25, acetylcholine release into the synaptic cleft is blocked, the motor nerve cannot signal the muscle fibre to contract, and the targeted muscle relaxes. New axon terminals eventually sprout and restore neuromuscular signalling, at which point clinical effect wanes.
Specifications
Common application zones
Application zones below are common indications for which botulinum toxin type A is used by practitioners. Specific dosing per zone is determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Contraindications
Frequently asked questions
ReNTOX 200U is the 200-unit single-vial format of Pharma Research Bio’s botulinum toxin type A. Each single-use vial contains 200 units of lyophilized white powder, reconstituted with 0.9% sterile saline before injection. Manufactured in the Republic of Korea.
ReNTOX 200U is manufactured by Pharma Research Bio Co., Ltd., part of the Pharma Research Group in the Republic of Korea.
ReNTOX 200U contains 200 units of botulinum toxin type A per vial; ReNTOX 100U contains 100 units. Both share the same active ingredient, Pharma Research Bio proprietary working strain, freeze-drying process, and excipient profile.
Both are products of the Pharma Research Group, but they are very different categories. Rejuran is a polynucleotide skin-booster product family. ReNTOX is a botulinum toxin type A neuromodulator.
ReNTOX 200U is freeze-dried (lyophilized). After freeze-drying, a visible white powder cake or thin layer remains in the vial. This is distinct from vacuum-dried botulinum toxins which can appear nearly empty in the vial.
Common aesthetic application zones include glabellar lines, forehead lines, lateral canthal lines, masseter contouring, brow lift refinement, mentalis muscle, and platysma bands. The 200U pack is particularly suited for multi-zone single-patient treatments or shared-vial multi-patient protocols.
Both are 200-unit Korean freeze-dried botulinum toxin type A products from different manufacturers. ReNTOX is manufactured by Pharma Research Bio. Botulax is manufactured by Hugel Pharma using the CBFC26 strain.
Both are 200-unit Korean freeze-dried botulinum toxin type A products from different manufacturers. ReNTOX is manufactured by Pharma Research Bio. Meditoxin is manufactured by Medytox using the Hall A-hyper strain.
Onset and duration vary with individual anatomy, muscle mass, metabolism, treatment zone, and dosing strategy. Practitioners can refer to published clinical literature for general expectations.
Store unopened vials at 2–8 °C, protected from light. Do not freeze. After reconstitution with 0.9% sterile saline, use within 24 hours when stored refrigerated.

Amanda K. –
Don’t let the price fool you, this is high-end stuff. I compared this to Innotox and Nabota feels more “stable.” I used a 1:4 dilution for my pores and the skin texture improvement was insane. My face looks filtered in real life. Will definitely stick with this for my maintenance routine.
Emily R –
Just received my 20 vials of ReNTox from fillersfairy. The bulk discount saved me a solid 8%, which is way better than other suppliers I checked. Shipping was fast—tracking updated in real time, so I knew exactly when it’d arrive. The product itself exactly as described. My patients love the subtle but lasting results . Will definitely reorder.