Maypharm Co., Ltd. · Republic of Korea
Metox 200U by Maypharm Co., Ltd. is the higher-unit-count single-vial format of Metox botulinum toxin type A — 200 units of Clostridium botulinum as vacuum-dried product for reconstitution. Maypharm is a Korean pharmaceutical company operating its own botulinum toxin production line. The 200-unit pack is positioned for multi-zone single-patient sessions or multi-patient shared-vial protocols.
This product is vacuum-dried. The vial may appear nearly empty before reconstitution — this is normal product appearance, not a defect. The full dose is present and dissolves into a clear, colourless solution when reconstituted with sterile saline.
Why this product is different
Metox 200U doubles the unit count per vial compared with Metox 100U, supporting multi-zone single-patient treatments or shared-vial multi-patient protocols. Maypharm’s botulinum toxin production platform uses a proprietary working strain and vacuum-drying manufacturing process — the same as Metox 100U. Because Metox is vacuum-dried, the 200U vial may appear nearly empty before reconstitution — this is normal product appearance.
Mechanism of action
Botulinum toxin type A is a presynaptic neuromuscular blocker. Following injection into target muscle, the toxin’s heavy chain binds to specific receptors on motor nerve terminals; the light chain is internalised into the nerve cytoplasm, where it enzymatically cleaves SNAP-25 — a SNARE complex protein required for acetylcholine vesicle fusion at the neuromuscular junction. Without SNAP-25, acetylcholine release into the synaptic cleft is blocked, the motor nerve cannot signal the muscle fibre to contract, and the targeted muscle relaxes. New axon terminals eventually sprout and restore neuromuscular signalling, at which point clinical effect wanes.
Specifications
Common application zones
Application zones below are common indications for which botulinum toxin type A is used by practitioners. Specific dosing per zone is determined by the treating practitioner based on individual patient anatomy and clinical judgment.
Contraindications
Frequently asked questions
Metox 200U is the 200-unit single-vial format of Maypharm’s vacuum-dried botulinum toxin type A. Each single-use vial contains 200 units of botulinum toxin type A, reconstituted with 0.9% sterile saline before injection.
Metox 200U is manufactured by Maypharm Co., Ltd. in the Republic of Korea.
Metox 200U uses vacuum-drying. The vial may appear nearly empty or have only a faint dried film — this is normal vacuum-dried product appearance. The full 200 units of botulinum toxin type A are present and dissolve when reconstituted with sterile saline.
Metox 200U contains 200 units of botulinum toxin type A per vial; Metox 100U contains 100 units. Both share the same active ingredient, Maypharm proprietary working strain, and vacuum-drying process.
Common aesthetic application zones include glabellar lines, forehead lines, lateral canthal lines, masseter contouring, mentalis muscle, and platysma bands. The 200U pack is particularly suited for multi-zone single-patient treatments or shared-vial multi-patient protocols.
Both are 200-unit vacuum-dried Korean botulinum toxin type A products from different manufacturers. Metox is manufactured by Maypharm. Toxta is manufactured by JETEMA Co., Ltd.
Both are 200-unit vacuum-dried Korean botulinum toxin type A products from different manufacturers. Metox is manufactured by Maypharm. INIBO is manufactured by INI Bio (GC Wellbeing subsidiary).
Both are 200-unit vacuum-dried Korean botulinum toxin type A products. Metox is manufactured by Maypharm. Nabota is manufactured by Daewoong Pharmaceutical.
Onset and duration vary with individual anatomy, muscle mass, metabolism, treatment zone, and dosing strategy.
Store unopened vials at 2–8 °C, protected from light. Do not freeze. After reconstitution with 0.9% sterile saline, use within 24 hours when stored refrigerated.

Susan K. –
At 54, my ’11s’ looked like canyon cracks. Tried Metox after my derm recommended their high purity. Noticeably softer lines by weekend brunch with the girls – and I’m not even at the 2-week peak yet! Mixes smoothly with the saline. Feels less ‘puffy’ than other brands I’ve tried.