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Vitaran i PN 1ml×2
Polynucleotide (Periocular) · PN 2% (20 mg/mL)
Quick Answer
Vitaran i PN is a 2% polynucleotide injectable formulated for the delicate periocular area. Each syringe delivers 20 mg/mL of purified salmon-trout-derived PN chains (500–5000 base pairs) optimised for fibroblast activation. The two-syringe pack supports one full bilateral periocular session or split treatment across two visits, with results building over 3–4 sessions spaced 2–3 weeks apart.
Last Reviewed
May 19, 2026
Manufacturer specification cross-verified
Treatment Protocol
3–4 sessions, 2–3 weeks apart. Maintenance every 4 months.
Why This Skinbooster Is Different
Vitaran i positions specifically for the periocular indication — where skin is thinnest and PN's biological signaling matters more than HA's water-binding. The 20 mg/mL concentration is at the upper end of the periocular PN category, and HPLC-verified molecular distribution keeps chain length optimal for receptor engagement. Two 1 mL syringes cover bilateral eyes in a single session.
Mechanism of Action
Polynucleotide Fibroblast Activator (periocular focus). Long-chain salmon DNA fragments (PN) deliver sustained fibroblast signalling. The 250–800 kDa MW range is optimal for fibroblast receptor engagement and dermal residence. In the periocular anatomy, where skin is thinnest, PN restores quality without correcting volume — the appropriate intervention for tissue quality rather than structural deficit.
Specifications
Clinical Indications
- Periocular fine lines and crow's feet
- Dark circles (vascular and pigmentary)
- Lower eyelid skin laxity (mild)
- Thin, fragile periocular skin
Compare Within Skinbooster Category
| Product | Active(s) | Mechanism | Protocol | Duration |
|---|---|---|---|---|
| Vitaran i PN 1ml×2 | PN 2% (20 mg/mL) | Polynucleotide Fibroblast Activator (periocular focus) | 3–4 sessions, 2–3 weeks apart. Maintenance every 4 months. | 4–6 months after the initial course |
| Rejuran I 1ml | PN 2% (DOT™ Technology) | DOT™ Polynucleotide Fibroblast Activator (periocular) | 3 sessions, 3–4 weeks apart. Maintenance every 4 months. | 3–6 months after the initial 3-session course |
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Frequently Asked Questions
Source verification: → HP Cell Vitaran (LG Chem Life Sciences) (manufacturer) · → EU MDR (CE marking framework)
Related Skin Boosters
Regulatory Notice. CE-marked Class III medical device. Manufactured under KGMP. Endotoxin tested <0.25 EU/mL. This product is manufactured outside the United States; FDA approval status is product-specific. For licensed healthcare professionals only. Practitioners are responsible for verifying regulatory status of this product in their jurisdiction before clinical use. Not for retail sale. Pricing subject to change.
Sophia L. –
Took advantage of the 5% discount on my first order, and wow, shipping was faster than my Amazon Prime. Used Vitaran II for my under-eyes less crepey, more bounce. FillersFairy’s checkout didn’t make me jump through hoops, and the package arrived chilled. Already planning my next buy.
Jessica T. –
I’ve tried other PN boosters before, but Vitaran II is next-level. My skin feels plumper after just two sessions, and those little forehead lines? Way less obvious now. Compared to other sites, their prices are legit, and I actually got what I paid for.